Protein Alignment RpIII128 and Polr1b

DIOPT Version :9

• Sequence 1: NP_523706.1
• Gene: RpIII128 / 36289
• FlyBaseID: FBgn0004463
• Length: 1137
• Species: Drosophila melanogaster
• Sequence 2: NP_113961.2
• Gene: Polr1b / 83582
• RGDID: 620822
• Length: 1135
• Species: Rattus norvegicus
• Alignment Length: 1219
• Identity: 358/1219 - (29%)
• Similarity: 560/1219 - (45%)
• Gaps: 196/1219 - (16%)

  Fly    20 DSKDWSVP----IKPLTEKWKLVPAFLQ---VKGLVKQHIDSFNHFINVDIKKIVKANELVTSGA 77
            ||:..::|    :|.||:....||...|   ::.|.:.|:||||:.:...:...|:        |
  Rat     4 DSRWRNLPSGPSLKHLTDPSYAVPPEQQKAALQDLTRAHVDSFNYAVLEGLSHAVQ--------A 60

  Fly    78 DPLFYLKYLDVRVGKPDIDDGFN---ITKATT-------PHECRLRDTTYSAPITVDIEY-TRGT 131
            .|.|...:.|.|:....:|...:   :.|.|.       |.|||.|.:||...:|.||.: ..|.
  Rat    61 IPPFEFAFKDERISLTIVDAAISPPAVPKGTICKELNIYPAECRGRRSTYRGKLTADISWAVNGV 125

  Fly   132 QR--IKRNNLLIGRMPLMLRCSNCALTGKSEFELSKLNECPLDPGGYFVVRGQEKVI-------- 186
            .:  ||:   .:|.:|:|::...|.|.......|.:.:|...:.||||::.|.||||
  Rat   126 PKGIIKQ---FLGYVPIMVKSKLCNLYNLPPQVLIEHHEEAEEMGGYFIINGIEKVIRMLIMPRR 187

  Fly   187 -----LIQEQLSWNKMLTEDFNGVVQC------QVTSSTHEKKSRTLVLS---KHGKYYLKHNSM 237
                 :|:.:.....:....|...:.|      .|..:.|..::.|::|:   :...::|
  Rat   188 NFPIAMIRPKWKSRGLGYTQFGVSIHCVREEHSAVNMNLHYVENGTVMLNFIYRKELFFL----- 247

  Fly   238 TDDIPIVVIFKALGVVSDQEI-QSLIGIDSKSQNRFGASLIDAYNLKV------FTQQRALEYMG 295
                |:....|||...||.:| |.|  |..|.::.|..:.: :..|::      .||::.|:|:|
  Rat   248 ----PLGFALKALVSFSDYQIFQEL--IKGKEEDSFFKNSV-SQMLRIVMEEGCHTQKQVLDYLG 305

  Fly   296 SKLVVKRFQSATTKTPSEEARELLLT-TILAHVP--VDNFNLQMKAIYVSMMVRRVMAAELDKTL 357
            .:..||  .|.....|:.||.|.|.. .|..|:.  .|.|.|      :.:|.|::.|....:.:
  Rat   306 ERFRVK--LSLPDWYPNAEAAEFLFNQCICIHLKSNTDKFYL------LCLMTRKLFALARGECM 362

  Fly   358 FDDRDYYGNKRLELAGSLLSMMFEDLFKRMNW--ELKTIADKNIPK--VKAAQFDVVK-HMRAAQ 417
            .|:.|...|:.:...|.|..|..::  |..||  .:|...||...|  |.....:::| .....:
  Rat   363 EDNPDSLVNQEVLTPGQLFLMFLKE--KMENWLLSIKIALDKRAQKTNVSINNENLMKIFSMGTE 425

  Fly   418 ITAGLESAISSGNWTIKR---FKMERAGVTQVLSRLSYISALGMMTRVN--SQFEKTRKVSGPRS 477
            :|...|..:::||...|.   | |:.:|:..|..:|::|..|.....|:  :.|.|.|..: .|.
  Rat   426 LTRPFEYLLATGNLRSKTGLGF-MQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTT-VRK 488

  Fly   478 LQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTE-VEERPVMIVAFNAGVEDIREVSGNPINNP 541
            |.|..||.|||..||:|..|||:.:|..:..:.|: |....:..:....||..:......|.:
  Rat   489 LLPESWGFLCPVHTPDGAPCGLLNHLTAVCEVVTKFVYTASIPALLCGLGVTPVDAAPCRPYS-- 551

  Fly   542 NVFLVFINGNVLG-----LTLNHKHLVRNLRYMRRK--------------GRMGSYVSVHTSYTQ 587
            :.:.|.::|.::|     |.......:|..:.:|.:              |:...|..
  Rat   552 DCYPVLLDGVMVGWVDKELAPEVADTLRRFKVLRERRVPPWMEVALIPMTGKPSLYPG------- 609

  Fly   588 RCIYIHTDGGRLCRPYVIVENRRPLVKQHHLDELNRGIRKFDDFLLDGLIEYLDVNEENDSFIAW 652
              :::.|...||.||   |:|            |..|..:     |.|.:|.|.:|      ||.
  Rat   610 --LFLFTTPCRLVRP---VQN------------LELGKEE-----LVGTMEQLFMN------IAI 646

  Fly   653 NEDQI-EDRTTHLEIEPFTLLGVCAGLVPYPHHNQSPRNTYQCAMGKQAMGMIGYNQKNRIDSLM 716
            .||:: ...:||.|:.|.:||.|.|..:|:..|||||||.|||.||||.||......::|.|:.:
  Rat   647 FEDEVFGGVSTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKL 711

  Fly   717 YNLVYPHAPMVKSKTIELTNFDKLPAGQNATVAVMSYSGYDIEDALILNKASIDRGYGRCLVYKN 781
            |.|..|.:|:|:....:..:.|..|.|.||.|||:||:|||:|||:|:||||.:||:....|||:
  Rat   712 YRLQTPQSPLVRPCMYDHYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKS 776

  Fly   782 SKCTVKRYANQTFDRIMGPMKDALTNKVIFKHDVLDTDGIVAPGEQVQNKQIMINKEMPAVTSMN 846
            ....:.....|..|.::..:|.. ..:|:.|   ||.||:...|.:::...       |....:|
  Rat   777 EFIDLSEKFKQGDDSLVFGVKPG-DPRVMQK---LDNDGLPFIGAKLEFGD-------PYYGYLN 830

  Fly   847 PLQGQSAQVPYTAVPISYKGPEPSYIERVMVSANAEEDFLIK---ILLRQTRIPEIGDKFSSRHG 908
            ...|:       ...:.||..|...::.:.|.:|.......|   :.:|..|.|.|||||:||||
  Rat   831 LNTGE-------GFVVYYKSKENCVVDNIKVCSNDTGSGKFKCVCVTVRVPRNPTIGDKFASRHG 888

  Fly   909 QKGVTGLIVEQEDMPFNDFGICPDMIMNPHGFPSRMTVGKTLELLGGKAGLLEGKFHYGTAF--- 970
            |||:...:...|||||.:.|:.||::.||||||||||:|..:|.:.||:..|.|..|..|.|
  Rat   889 QKGILSRLWPAEDMPFTESGMMPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFS 953

  Fly   971 -GGSKVEDIQAELERHGFNYVGKDFFYSGITGTPLEAYIYSGPVYYQKLKHMVQDKMHARARGPK 1034
             ..|.:|.....|:..|:|:.|.:..||||:|..|||.|:.|.||||:|:|||.||...|..|.:
  Rat   954 EENSALEYFGEMLKAAGYNFYGTERLYSGISGMELEADIFIGVVYYQRLRHMVSDKFQVRTTGAR 1018

  Fly  1035 AVLTRQPTQGRSREGGLRLGEMERDCLISYGASMLIMERLMISSDAFEVDVCRTCGRMAY----- 1094
            ..:|.||..||:.:||:|.||||||.|:::|.|.|:.:||...||.....||..||.:..
  Rat  1019 DKVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEK 1083

  Fly  1095 --CSW---------CHFCQSSANVSKISMPYACKLLFQELTSMNVVPKM 1132
              .||         |..|..|.::..:|:||..:....||.:||:..|:
  Rat  1084 PPPSWSAMRNRKYNCTVCGRSDSIDTVSVPYVFRYFVAELAAMNIKVKL 1132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpIII128	NP_523706.1	PRK08565	34..1135	CDD:236291	352/1201 (29%)
		RNA_pol_B_RPB2	47..1133	CDD:238353	349/1185 (29%)
		RNA_pol_Rpb2_2	210..370	CDD:282427	42/172 (24%)
		RNA_pol_Rpb2_4	546..607	CDD:282431	13/79 (16%)
		RNA_pol_Rpb2_5	628..668	CDD:282432	12/40 (30%)
Polr1b	NP_113961.2	RNA_pol_B_RPB2	38..1133	CDD:238353	349/1185 (29%)
		RNA_pol_Rpb2_2	186..375	CDD:398318	45/208 (22%)
		RNA_pol_Rpa2_4	563..616	CDD:399696	7/61 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0085
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D42570at2759
OrthoFinder	1	1.000	-	-		FOG0000346
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820