Protein Alignment Polr3B and NRPD2A

DIOPT Version :10

• Sequence 1: NP_523706.1
• Gene: Polr3B / 36289
• FlyBaseID: FBgn0004463
• Length: 1137
• Species: Drosophila melanogaster
• Sequence 2: NP_189020.2
• Gene: NRPD2A / 821960
• AraportID: AT3G23780
• Length: 1172
• Species: Arabidopsis thaliana
• Alignment Length: 1233
• Identity: 379/1233 - (30%)
• Similarity: 586/1233 - (47%)
• Gaps: 180/1233 - (14%)

  Fly     6 MGDHNVEATTWDPGDSKDWSVPIKPLTEKW------KLVPAFLQVKGLVKQHIDSFNHFINVDIK 64
            |.|.:::....:..::....:.:..|.|.:      |...:|....||:...::|:|:||...::
plant     1 MPDMDIDVKDLEEFEATTGEINLSELGEGFLQSFCKKAATSFFDKYGLISHQLNSYNYFIEHGLQ 65

  Fly    65 KIVKA-NELVTSGADPLF-------------YLKYLDVRVGKPDIDDGFNITKAT--TPHECRLR 113
            .:.:: .|::   .:|.|             .:|:.:|.|.||..   |:..|..  .|...||:
plant    66 NVFQSFGEML---VEPSFDVVKKKDNDWRYATVKFGEVTVEKPTF---FSDDKELEFLPWHARLQ 124

  Fly   114 DTTYSAPITVDIE-------------YTRGTQR--------IKRNNLLIGRMPLMLRCSNCALTG 157
            :.||||.|.|:::             :..|...        :|:.::|||.:|:|::...|..:.
plant   125 NMTYSARIKVNVQVEVFKNTVVKSDKFKTGQDNYVEKKILDVKKQDILIGSIPVMVKSILCKTSE 189

  Fly   158 KSEFELSKLNECPLDPGGYFVVRGQEKVILIQEQLS----W--NKMLTEDFNG-------VVQCQ 209
            |.: |..|..:|..|.|||||::|.|||.:.|||:.    |  |...|..|..       :|:..
plant   190 KGK-ENCKKGDCAFDQGGYFVIKGAEKVFIAQEQMCTKRLWISNSPWTVSFRSENKRNRFIVRLS 253

  Fly   210 VTSSTHEKKSRTLVLSKHGKYYLKHNSMTDDIPIVVIFKALGVVSDQEIQSLI---GIDSKSQNR 271
            ......:.|.|..||:   .|:|     :.:||:.::|.||||.||:|...||   |.|:...|.
plant   254 ENEKAEDYKRREKVLT---VYFL-----STEIPVWLLFFALGVSSDKEAMDLIAFDGDDASITNS 310

  Fly   272 FGASL--IDAYNLKVFTQQRALEYMGSKLVVKRFQSATTKTPSEEARELLLTTILAHVPVDNFNL 334
            ..||:  .||..........||.|:..::...:|      .|:|...|.|...:...:.    :|
plant   311 LIASIHVADAVCEAFRCGNNALTYVEQQIKSTKF------PPAESVDECLHLYLFPGLQ----SL 365

  Fly   335 QMKAIYVSMMVRRVMAAELDKTLFDDRDYYGNKRLELAGSLLSMMFEDLFKRMNWELKT-IADKN 398
            :.||.::..||:.::.:...|...::||.:.|||:||||.||..           |::. :|...
plant   366 KKKARFLGYMVKCLLNSYAGKRKCENRDSFRNKRIELAGELLER-----------EIRVHLAHAR 419

  Fly   399 IPKVKAAQFDVVKHMR-------------AAQITAGLESAISSGNWTIKRFKMER-AGVTQVLSR 449
            ....:|.|    ||:.             |:.||.||..|.|:|.|:....|||| :||...|.|
plant   420 RKMTRAMQ----KHLSGDGDLKPIEHYLDASVITNGLSRAFSTGAWSHPFRKMERVSGVVANLGR 480

  Fly   450 LSYISALGMMTRVNSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTEVE 514
            .:.:..|..:.|...|...|.||...|...||.||.:|...||:||.||||||::|:..::|:..
plant   481 ANPLQTLIDLRRTRQQVLYTGKVGDARYPHPSHWGRVCFLSTPDGENCGLVKNMSLLGLVSTQSL 545

  Fly   515 ERPVMIVAFNAGVEDIREVSGNPINNPNVFLVFINGNVLGLTLNHKHLVRNLRYMRRKGRMGSYV 579
            | .|:...|..|:|::.:.:..|:...:  .|.:||:.:||..:.:..|..|:..||:..:...:
plant   546 E-SVVEKLFACGMEELMDDTCTPLFGKH--KVLLNGDWVGLCADSESFVAELKSRRRQSELPREM 607

  Fly   580 SVHTSYTQRCIYIHTDGGRLCRPYVIVENRRPLVKQHHLDELNRGIRKFDDFLLDGLIEYLDVNE 644
            .:........:.|.||.|||.||.::|||.:.| ||....:.     .||..|..|::|.:.:.|
plant   608 EIKRDKDDNEVRIFTDAGRLLRPLLVVENLQKL-KQEKPSQY-----PFDHLLDHGILELIGIEE 666

  Fly   645 ENDSFIAWNEDQI--EDRT-THLEIEPFTLLGVCAGLVPYPHHNQSPRNTYQ----CAMGKQAMG 702
            |.|...||...|:  |.:. ||.|::...||||...:||:.:|:...|..||    |   :||:|
plant   667 EEDCNTAWGIKQLLKEPKIYTHCELDLSFLLGVSCAVVPFANHDHGRRVLYQSQKHC---QQAIG 728

  Fly   703 MIGYNQKNRIDSLMYNLVYPHAPMVKSKTIELTNFDKLPAGQNATVAVMSYSGYDIEDALILNKA 767
            ....|...|.|:|...|.||..|:.|:...|....:.|..||||.|||..:.||:.||::::|||
plant   729 FSSTNPNIRCDTLSQQLFYPQKPLFKTLASECLKKEVLFNGQNAIVAVNVHLGYNQEDSIVMNKA 793

  Fly   768 SIDRGYGRCLVYKNSKCTVKRYANQTFDRIMGPMKDALTNKVIFKHDVLDTDGIVAPGEQVQNKQ 832
            |::||..|....::.|..|....::...::...::...|:..|.|.|.|:.||....|..:....
plant   794 SLERGMFRSEQIRSYKAEVDAKDSEKRKKMDELVQFGKTHSKIGKVDSLEDDGFPFIGANMSTGD 858

  Fly   833 IMINK--EMPAVTSMNPLQGQSAQVPYTAVPISYKGPEPSYIERVMVSANAEEDFLIKILLRQTR 895
            |:|.:  |..|..|                 |..|..|...:::|::|:|.|......:.|||.|
plant   859 IVIGRCTESGADHS-----------------IKLKHTERGIVQKVVLSSNDEGKNFAAVSLRQVR 906

  Fly   896 IPEIGDKFSSRHGQKGVTGLIVEQEDMPFNDFGICPDMIMNPHGFPSRMTVGKTLELLGGKAGLL 960
            .|.:||||||.||||||.|.:.||::.||...||.||:::|||.||||.|.|:.||....| |:.
plant   907 SPCLGDKFSSMHGQKGVLGYLEEQQNFPFTIQGIVPDIVINPHAFPSRQTPGQLLEAALSK-GIA 970

  Fly   961 -----EGK-------FHYGTAFGGSKVEDIQAELERHGFNYVGKDFFYSGITGTPLEAYIYSGPV 1013
                 ||.       ..:.|.|....|.:|..:|.|.||:..|.:..|:|.:|..:.:.|:.||.
plant   971 CPIQKEGSSAAYTKLTRHATPFSTPGVTEITEQLHRAGFSRWGNERVYNGRSGEMMRSMIFMGPT 1035

  Fly  1014 YYQKLKHMVQDKMHARARGPKAVLTRQPTQGRSREGGLRLGEMERDCLISYGASMLIMERLMISS 1078
            :||:|.||.:||:..|..||...|||||...|.|.||::.|||||||||::|||..:.|||...|
plant  1036 FYQRLVHMSEDKVKFRNTGPVHPLTRQPVADRKRFGGIKFGEMERDCLIAHGASANLHERLFTLS 1100

  Fly  1079 DAFEVDVCRTC-------------GRMAYCSWCHFCQSSANVSKISMPYACKLLFQELTSMNV 1128
            |:.::.:||.|             ||.....:|..|.||.:|.::.:||..|||.|||.||.:
plant  1101 DSSQMHICRKCKTYANVIERTPSSGRKIRGPYCRVCVSSDHVVRVYVPYGAKLLCQELFSMGI 1163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr3B	NP_523706.1	RNA_pol_B_RPB2	47..1133	CDD:238353	372/1186 (31%)
		RNA_pol_Rpb2_4	546..607	CDD:428012	17/60 (28%)
		RNA_pol_Rpb2_5	628..668	CDD:428013	15/42 (36%)
NRPD2A	NP_189020.2	RNA_pol_B_RPB2	48..1168	CDD:238353	372/1186 (31%)
		RNA_pol_Rpb2_4	574..635	CDD:428012	17/60 (28%)