Protein Alignment Polr3B and rpc2

DIOPT Version :10

• Sequence 1: NP_523706.1
• Gene: Polr3B / 36289
• FlyBaseID: FBgn0004463
• Length: 1137
• Species: Drosophila melanogaster
• Sequence 2: NP_593690.1
• Gene: rpc2 / 2543393
• PomBaseID: SPAC4G9.08C
• Length: 1165
• Species: Schizosaccharomyces pombe
• Alignment Length: 1119
• Identity: 665/1119 - (59%)
• Similarity: 845/1119 - (75%)
• Gaps: 9/1119 - (0%)

  Fly    27 PIKPLTEKWKLVPAFLQVKGLVKQHIDSFNHFINVDIKKIVKANELVTSGADPLFYLKYLDVRVG 91
            |:..:.:||:|:||||:||||||||:||:|:|::||:||||:|||.|||..:|.|||||||:|||
pombe    43 PVPTIEDKWQLLPAFLKVKGLVKQHLDSYNYFVDVDLKKIVQANEKVTSDVEPWFYLKYLDIRVG 107

  Fly    92 KPDIDDGFNITKATTPHECRLRDTTYSAPITVDIEYTRGTQRIKRNNLLIGRMPLMLRCSNCALT 156
            .|...|...|..:.:||||||||.||.|.|.||||||||.|.::|.|:.|||||:|||.:.|.|:
pombe   108 APVRTDADAIQASISPHECRLRDLTYGANIYVDIEYTRGKQVVRRRNVPIGRMPVMLRSNKCVLS 172

  Fly   157 GKSEFELSKLNECPLDPGGYFVVRGQEKVILIQEQLSWNKML--TEDFNGVVQCQVTSSTHEKKS 219
            ||:|.|::.||||||||||||:|:|.|||||:|||||.|:::  .|...|:.|..|||||||:||
pombe   173 GKNEMEMAALNECPLDPGGYFIVKGTEKVILVQEQLSKNRIIVEAEPKKGLWQASVTSSTHERKS 237

  Fly   220 RTLVLSKHGKYYLKHNSMTDDIPIVVIFKALGVVSDQEIQSLI-GIDSKSQNRFGASLIDAYNLK 283
            :|.|::|:||.||||||:.|||||||:.||:|:.|||||..|: |.::..|:.|..|:.:...|.
pombe   238 KTYVITKNGKLYLKHNSVADDIPIVVVLKAMGLQSDQEIFELVAGAEASYQDLFAPSIEECAKLN 302

  Fly   284 VFTQQRALEYMGSKLVVKRFQSATTKTPSEEARELLLTTILAHVPVDNFNLQMKAIYVSMMVRRV 348
            ::|.|:||||:|:::.|.|...|....|.|||.|:|...:|||:.|.|...:.||:|:.:|.|||
pombe   303 IYTAQQALEYIGARVKVNRRAGANRLPPHEEALEVLAAVVLAHINVFNLEFRPKAVYIGIMARRV 367

  Fly   349 MAAELDKTLFDDRDYYGNKRLELAGSLLSMMFEDLFKRMNWELKTIADKNIPKV-KAAQFDVVKH 412
            :.|.:|....|||||.|||||||||.||:::||||||:.|.:||...||.:.|. :..:||....
pombe   368 LMAMVDPLQVDDRDYVGNKRLELAGQLLALLFEDLFKKFNSDLKLNIDKVLKKPHRTQEFDAYNQ 432

  Fly   413 M--RAAQITAGLESAISSGNWTIKRFKMERAGVTQVLSRLSYISALGMMTRVNSQFEKTRKVSGP 475
            :  .:..||.|:..|:|:|||::|||||||||||.||||||||||||||||:.||||||||||||
pombe   433 LTVHSDHITQGMVRALSTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRITSQFEKTRKVSGP 497

  Fly   476 RSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTEVEERPVMIVAFNAGVEDIREVSGNPINN 540
            ||||.||:||||.|||||||||||||||||||||||:.||.|::.:|:..|:|||..:||..:::
pombe   498 RSLQASQFGMLCTSDTPEGEACGLVKNLALMTHITTDEEEEPIIKLAYAFGIEDIHVISGRELHS 562

  Fly   541 PNVFLVFINGNVLGLTLNHKHLVRNLRYMRRKGRMGSYVSVHTSYTQRCIYIHTDGGRLCRPYVI 605
            ...:||::||.:||::......|.:.|.:||.|::..::.:..:..||.::|.|||||:|||.:|
pombe   563 HGTYLVYLNGAILGISRYPSLFVASFRKLRRSGKISPFIGIFINTHQRAVFISTDGGRICRPLII 627

  Fly   606 VENRRPLVKQHHLDELNRGIRKFDDFLLDGLIEYLDVNEENDSFIAWNEDQIEDRTTHLEIEPFT 670
            |:|..|.|:..|:..|..|...|:|||..||:||:||||||||.|:..|..|...||||||||||
pombe   628 VQNGLPKVESKHIRLLKEGKWGFEDFLKQGLVEYVDVNEENDSLISVYERDITPDTTHLEIEPFT 692

  Fly   671 LLGVCAGLVPYPHHNQSPRNTYQCAMGKQAMGMIGYNQKNRIDSLMYNLVYPHAPMVKSKTIELT 735
            :||..|||:|||||||||||||||||||||:|.|.|||..|||:|:|.:|||..||||:|||||.
pombe   693 ILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQLQRIDTLLYLMVYPQQPMVKTKTIELI 757

  Fly   736 NFDKLPAGQNATVAVMSYSGYDIEDALILNKASIDRGYGRCLVYKNSKCTVKRYANQTFDRIMGP 800
            .:||||||||||||:||||||||||||:|||:|||||:|||.|:......|::|.|.|.|||..|
pombe   758 GYDKLPAGQNATVAIMSYSGYDIEDALVLNKSSIDRGFGRCQVFHKHSVIVRKYPNGTHDRIGDP 822

  Fly   801 MKDALTNKVIFKHDVLDTDGIVAPGEQVQNKQIMINKEMPAVTSMNPL---QGQSAQVPYTAVPI 862
            .:|..|.:|::||.|::.||:...|.:||..||.:||:.|.....|.:   ..|:.:..|.|.|:
pombe   823 QRDPETGEVVWKHGVVEDDGLAGVGCRVQPGQIYVNKQTPTNALDNSITLGHTQTVESGYKATPM 887

  Fly   863 SYKGPEPSYIERVMVSANAEEDFLIKILLRQTRIPEIGDKFSSRHGQKGVTGLIVEQEDMPFNDF 927
            :||.|||.||::||::....:..|||:|:||||.||:|||||||||||||.|:||:||||||||.
pombe   888 TYKAPEPGYIDKVMLTTTDSDQTLIKVLMRQTRRPELGDKFSSRHGQKGVCGVIVQQEDMPFNDQ 952

  Fly   928 GICPDMIMNPHGFPSRMTVGKTLELLGGKAGLLEGKFHYGTAFGGSKVEDIQAELERHGFNYVGK 992
            |||||:|||||||||||||||.:|||.||.|:|.|...|||.|||:||||....|..||:||.||
pombe   953 GICPDIIMNPHGFPSRMTVGKMIELLSGKVGVLRGTLEYGTCFGGTKVEDASRILVEHGYNYSGK 1017

  Fly   993 DFFYSGITGTPLEAYIYSGPVYYQKLKHMVQDKMHARARGPKAVLTRQPTQGRSREGGLRLGEME 1057
            |...|||||..|||||:.||:|||||||||.||||||||||:||||||||:||||:|||||||||
pombe  1018 DMLTSGITGETLEAYIFMGPIYYQKLKHMVMDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEME 1082

  Fly  1058 RDCLISYGASMLIMERLMISSDAFEVDVCRTCGRMAYCSWCHFCQSSANVSKISMPYACKLLFQE 1122
            |||||:||||.|::|||||||||.:||||..||.:.|..||:.|||:..|.|:::|||.||||||
pombe  1083 RDCLIAYGASQLLLERLMISSDACDVDVCGQCGLLGYKGWCNSCQSTREVVKMTIPYAAKLLFQE 1147

  Fly  1123 LTSMNVVPKMILEN 1136
            |.|||:||::.||:
pombe  1148 LLSMNIVPRLALED 1161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr3B	NP_523706.1	RNA_pol_B_RPB2	47..1133	CDD:238353	652/1094 (60%)
		RNA_pol_Rpb2_4	546..607	CDD:428012	22/60 (37%)
		RNA_pol_Rpb2_5	628..668	CDD:428013	25/39 (64%)
rpc2	NP_593690.1	RNA_pol_B_RPB2	63..1157	CDD:238353	652/1093 (60%)
		RNA_pol_Rpb2_4	568..629	CDD:428012	22/60 (37%)
		RNA_pol_Rpb2_5	650..690	CDD:428013	25/39 (64%)