Protein Alignment 128up and DRG1

DIOPT Version :10

• Sequence 1: NP_536733.1
• Gene: 128up / 36288
• FlyBaseID: FBgn0010339
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: NP_004138.1
• Gene: DRG1 / 4733
• HGNCID: 3029
• Length: 367
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 297/367 - (80%)
• Similarity: 334/367 - (91%)
• Gaps: 0/367 - (0%)

  Fly     1 MSTILEKISAIESEMARTQKNKATSAHLGLLKAKLAKLRRELISPKGGGGGTGEAGFEVAKTGDA 65
            ||:.|.||:.||:|||||||||||:.|||||||:|||||||||:|||||||....||:|||||||
Human     1 MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDA 65

  Fly    66 RVGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDGKG 130
            |:|||||||||||||||||||||||||||||||||||||.|:|||||||||||||||||||||||
Human    66 RIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKG 130

  Fly   131 RGRQVIAVARTCNLIFMVLDCLKPLGHKKLLEHELEGFGIRLNKKPPNIYYKRKDKGGINLNSMV 195
            |||||||||||||||.:|||.||||||||::|:||||||||||.|||||.:|:||||||||.:..
Human   131 RGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATC 195

  Fly   196 PQSELDTDLVKTILSEYKIHNADITLRYDATSDDLIDVIEGNRIYIPCIYLLNKIDQISIEELDV 260
            ||||||.:.||:||:||||||||:|||.|||:||||||:||||:||||||:|||||||||||||:
Human   196 PQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDI 260

  Fly   261 IYKIPHCVPISAHHHWNFDDLLELMWEYLRLQRIYTKPKGQLPDYNSPVVLHNERTSIEDFCNKL 325
            |||:||||||||||.||||||||.:|:||:|.|||||||||||||.|||||...||::||||.|:
Human   261 IYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKI 325

  Fly   326 HRSIAKEFKYALVWGSSVKHQPQKVGIEHVLNDEDVVQIVKK 367
            |:::.||||||||||.||||.|||||.:|.|.||||:|||||
Human   326 HKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
128up	NP_536733.1	Rbg1	1..367	CDD:440777	295/365 (81%)
DRG1	NP_004138.1	Required for interaction with STK16. /evidence=ECO:0000269|PubMed:18184589	2..16		7/13 (54%)
		Rbg1	7..367	CDD:440777	292/359 (81%)