Protein Alignment 128up and DRG2

DIOPT Version :9

• Sequence 1: NP_536733.1
• Gene: 128up / 36288
• FlyBaseID: FBgn0010339
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: XP_005256556.1
• Gene: DRG2 / 1819
• HGNCID: 3030
• Length: 385
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 214/385 - (55%)
• Similarity: 265/385 - (68%)
• Gaps: 23/385 - (5%)

  Fly     4 ILEKISAIESEMARTQKNKATSAHLGLLKAKLAKLRRELISPKGGGGGTGEAGFEVAKTGDARVG 68
            ||||||.||.|:|||||||||..|||||||||||.|.:|:.|.......|| ||:|.|:|||||.
Human     3 ILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGE-GFDVMKSGDARVA 66

  Fly    69 FVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGCIKYKGAKIQLLDLPGIIEGAKDGKGRGR 133
            .:|||||||||.||.:....||.|:|||||||.:||.|:||||.|||||||||||||..||||||
Human    67 LIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGKGRGR 131

  Fly   134 QVIAVARTCNLIFMVLDCLKPLGHKKLLEHELEGFGIRLNKKPPNIYYKRKDKGGINLNSMVPQS 198
            ||||||||.::|.|:||..|....:.|||.|||..||||||..||||:|.|..|||:.||.|..:
Human   132 QVIAVARTADVIIMMLDATKGEVQRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVTLT 196

  Fly   199 ELDTDLVKTILSEYKIHNADITLRYDATSDDLIDVIEGNRIYIPCIYLLNKIDQISIEELDVIYK 263
            :....||:.||.||||.||::..|.|.:.|:.||||.|||:|:||:|:.|||||||:||:|.:.:
Human   197 QCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLAR 261

  Fly   264 IPHCVPISAHHHWNFDDLLELMWEYLRLQRIYTKPKGQ---------------------LPDYNS 307
            .|:.|.||.....|.|.|||::||||.|..||||.:||                     .||:..
Human   262 KPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRGQSQDGSVGPDVWLTFSPSCPAERPDFTD 326

  Fly   308 PVVLHNERTSIEDFCNKLHRSIAKEFKYALVWGSSVKHQPQKVGIEHVLNDEDVVQIVKK 367
            .::| .:..|:|..|:::|||:|.:||||||||:|.|:.||:||:.|.:..|||:|||||
Human   327 AIIL-RKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHEDVIQIVKK 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
128up	NP_536733.1	Rbg1	1..367	CDD:224085	212/383 (55%)
DRG2	XP_005256556.1	Rbg1	1..385	CDD:224085	212/383 (55%)
		P-loop_NTPase	<3..119	CDD:304359	78/116 (67%)
		DRG	63..295	CDD:206683	137/231 (59%)
		TGS_DRG_C	289..384	CDD:133436	37/95 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1163
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60797
OrthoDB	1	1.010	-	-		D348788at33208
OrthoFinder	1	1.000	-	-		FOG0001080
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.830