DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pds5 and AT1G77600

DIOPT Version :9

Sequence 1:	NP_001246271.1	Gene:	pds5 / 36286	FlyBaseID:	FBgn0260012	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_001185421.1	Gene:	AT1G77600 / 844095	AraportID:	AT1G77600	Length:	1424	Species:	Arabidopsis thaliana

Alignment Length:	1297	Identity:	282/1297 - (21%)
Similarity:	519/1297 - (40%)	Gaps:	279/1297 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 DELIRRLKTLANVLQTMDQDDN---------LYQQYIPLALHLLDDFFMQHPSRDVQLLIACCVA 75
            |.|::.|:.:||.|..:||...         :..:..||...::....:::...||.||:..||:
plant    25 DSLVKLLREVANTLSKIDQPSATNKEKGLKLIEAELRPLKKSIIKHALLKNRDNDVSLLVTVCVS 89

  Fly    76 DVLRVYAPEAPYKEQDQIKTIFKFFIKQLHGLKDPRDPSFKRYFYLLENLAFVKSFNMCFELEDC 140
            ::.|:.||..|: |.:.::.||..||.:...|.|...|.|.:...:||.::.:| |.:....|||
plant    90 ELFRILAPHLPF-EDEYLRDIFTLFIAEFSELSDTVSPYFSKRAKILETVSRLK-FCLLMLDEDC 152

  Fly   141 QEIFQDLFSTIFKIVNDQH--------SVK--------------VTNFFLDVLSPLITEADNLSV 183
            |::..::|:..|.:|.:.|        |:|              :.|..|.::|.::.|..|.|
plant   153 QDLVHEMFNMFFSLVREHHQQSLINQKSMKTQQRKANTQQTQHSLFNNILAIMSDVLEEEANSS- 216

  Fly   184 ELLDLILINIVEPYKSNNKFACQLTEQLLTKTGDALESTIKMFFNRALVMDKPNTKLSITNKIYD 248
             .:.:||.|:|:..:.....|.:|...|:.:..|.||..|..|.. :..|:|.:.:.::.:..::
plant   217 -FVVVILENLVKEGEDTTSGADKLASSLIERCADRLEPLICSFLT-SCFMEKDSIQTNLKDSYHE 279

  Fly   249 IIYELNRINAGLLCSVLPQLENKLLSTDDAERLKATTLLSRMFSEKD---SQLAKKYPNLLKIFF 310
            ||::::.|...:|.:|:|:|..:||:.....|:||..|..|:|::..   |...:.|.:|...|.
plant   280 IIFKISLIAPQMLLAVIPKLTQELLTDQVDVRIKALNLAGRIFAQPKHCLSSYVETYQDLYAEFL 344

  Fly   311 GRFCDITEPVRIKCVQSSMHFLLNHPS--LQHDITEKLRLRNHDLDEVVRHEVVMAIVETAKRDF 373
            .||.|.:..||:..::........:||  ....:...::.|..|.|:.||.:.::...:..|  |
plant   345 RRFSDKSAEVRMAALKCGKQCYFANPSGNKASGVLTAIQERLLDFDDRVRTQALIVACDIMK--F 407

  Fly   374 TLVLEAPDLLEIVRERTLDKKYKIRRDAMNGLAYIYKRAI--CEPNDLSTGLKVRVDWIKNKILH 436
            .:.....:|:....||..|||..:|:.|:..|..:|:...  |...|::  :....:.|..|||.
plant   408 NMKYVPLNLISEASERLRDKKISVRKKALQKLTEVYQDYCDKCSEGDMT--ITDNFEQIPCKILL 470

  Fly   437 GYYKVGLED--RLLVERLLITCLVPYKLAPEERMK---KLYHLLGDLDANATKAFVELQKN-QMK 495
            ...:...|:  ...:|.:|...|.|..|..||||:   :.:.::..:...:..:.:..::. |.:
plant   471 LCCEKNCEEFRSQNLELVLSDDLFPRLLPVEERMRHWVQCFAIMNHIHLKSLNSILSQKRRLQNE 535

  Fly   496 TRNTVSDW--IKLHHSKEFTPRVLSQLSAKQANIAKL---LPDPLKAAEYLTQFSNNLRKDAQLL 555
            .|:.::.|  .|:.:.:|...:       |::...||   .||..:|.:...:...  .:||.:.
plant   536 LRHCLTLWRKAKVDNIEEAQRK-------KKSYFVKLSACFPDASEAEDLFEKLDR--MRDASIF 591

  Fly   556 RCINIVLKRDVSCRECADTMGVLLKKLGAHVQSNLYYNTVKMLIERVASVMVDKESIGVLISLIE 620
            ..:.::|:      |.:.|...::|.:...:...::....|.|           :.|||..||.|
plant   592 DVLTLLLE------ELSSTNAQIIKVIIFSLLLFIFIFQEKFL-----------KMIGVKHSLFE 639

  Fly   621 -------------------QCIEKGSMCEEIGISAQEAGERGLKLLAMLSYVFSAHF-------- 658
                               ||: ...:|.....:.|.... .:|||.::..:|.::.
plant   640 FLRILSTKCSPSIFSSEHVQCL-LNQLCGSTSANTQLKAP-SIKLLLVILNMFPSYLRGSEKQFL 702

  Fly   659 ----FTDTSLRHLISLLSYEQDYVAPLVLKTLTHLGRYQPLIDDPTPAILDELAPVCKDFALIGT 719
                ..|::...||.:||....|::       .:.|.|.|:::           .||    |.||
plant   703 KLLEENDSAADELIVVLSKAAPYIS-------VNFGDYYPVLE-----------KVC----LEGT 745

  Fly   720 PKQAKHAVRCIFVNSQSSASTDGATSGAGSASTTTQTVHPIFNEIIETL--RLKLTPNCEHQRTK 782
            ..|.|.||..|             :|.|||:..:      :|:|:.|.|  .|....|.......
plant   746 RSQTKCAVSAI-------------SSLAGSSEKS------VFSELCEMLMDSLLCGRNIPTTLQS 791

  Fly   783 IVTLGHIAYNMPQAFLTPIKNMIARRIVKELLIQEVPAQRDYELP-EDSDWCAQEKLPPDTLCKL 846
            :..:|..:..........|.:.|.|      :.|..|:  |.:|| :.|..|...       |||
plant   792 LACVGQYSVLEYDNIYEDITSYIYR------VFQAEPS--DNQLPCDQSSGCCNS-------CKL 841

  Fly   847 DALKAMARWLLGLRTDEHAAQKTFRMLAAFVNQRG-------DLL----------GQNRLCGAEK 894
            .        :.||:|          ::.:|:.:.|       |||          |.:.:...|.
plant   842 K--------IYGLKT----------LVKSFLPRHGQVVRKIDDLLNILKKTLKSQGHDGIKSCED 888

  Fly   895 SW--LRLGAACAMLKVCEQKGVGDQYSAEQYLQLSQLMA-DPVPEVREIFARKLHKGLSRSLPRN 956
            :.  :||.||.|:|.:..:   .|.:.:.:..:|:.||| |....:.:.|..||:|.|:..:
plant   889 TGANVRLAAAKAVLLLSRK---WDLHISPEVFRLTILMAKDSNAFITKTFLTKLYKLLTEHM--- 947

  Fly   957 CLPLDFMGLYVLAGLETERKLQDLVRHYAETDVNKRREYLKTVA-MTSPDSSTESQSLHILPDYM 1020
             :|..:...:..:.....|.|.|....|....:||.....:|.. :...:|.|:|      |.||
plant   948 -IPSRYACAFSFSLSSPCRDLHDDSFRYINGFINKATRESRTCRDLDQGESLTDS------PVYM 1005

  Fly  1021 LAFAIPVLVHDPRFTN---HEDYVQLRKMEKC--LRFILEPLMA-------KRETFVHSFYKQLL 1073
            ..|.|.||.|||.|.:   .::::..|   .|  |..:|:.|::       .:||....|.  :.
plant  1006 TVFLIHVLAHDPEFPSEDCRDEHIYAR---FCGPLFSVLQVLLSINNNGFTIKETAPFLFC--IF 1065

  Fly  1074 QLIKHREFSLGSDKRDNYKMWALCDL---AMYIIDSKFSPFDGNTSTFSMPLA-----LPEMYYK 1130
            :.||..|.::  |.|...::..|.|:   |:.|:         |:...:.|.|     ||...|.
plant  1066 RAIKRAEDAV--DSRKTPRLHILADIGYSAVNIL---------NSIVVTSPQAPRSILLPSSLYS 1119

  Fly  1131 EPAVANFQNNDVYIPLDVYTLGAKSTSKAAATAMTTSRAAVAPKRPAEQSIMDDENPQENNL 1192
            ..::.:.||.            |||.::.|.......|.....:   .|..|.|:..|:::|
plant  1120 LTSITDNQNK------------AKSRTRNALEQSFIERIVHIFQ---SQISMHDQRCQKDSL 1166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pds5	NP_001246271.1	None
AT1G77600	NP_001185421.1	HEAT repeat	220..243	CDD:293787	6/22 (27%)
		HEAT repeat	295..321	CDD:293787	9/25 (36%)
		HEAT repeat	331..367	CDD:293787	8/35 (23%)
		HEAT repeat	376..402	CDD:293787	5/25 (20%)
		HEAT repeat	413..442	CDD:293787	9/28 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	188	1.000	Domainoid score	I965
eggNOG	1	0.900	-	-		E1_KOG1525
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I1399
OMA	1	1.010	-	-		QHG55449
OrthoDB	1	1.010	-	-		D69768at2759
OrthoFinder	1	1.000	-	-		FOG0001888
OrthoInspector	1	1.000	-	-		otm2641
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12663
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940