DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mppe and Mppe1

DIOPT Version :9

Sequence 1:	NP_001286327.1	Gene:	Mppe / 36285	FlyBaseID:	FBgn0259985	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001101905.1	Gene:	Mppe1 / 361344	RGDID:	1309184	Length:	394	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	81/400 - (20%)
Similarity:	149/400 - (37%)	Gaps:	112/400 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SLRVVNRNRLVCRGFVALTLLLVFFNEFIVYYMA--QSSWQPIDC-----KLDNCTRLLLIADPQ 60
            :..::.|.|::......:.:.::.|.|:.:||:.  :..|..:..     :.:...:.:.:||..
  Rat    12 NFHLLRRRRVLLLKLTVVVISVLLFCEYFIYYLVLFRCHWPEVKMPARGGRQEPVLKAMFLADTH 76

  Fly    61 ILGNSYDRSSHSPLARYDSDRYLAKTFERALAFTQPHIIVFLGDLLDEGNIATAQEYKQYVQRFR 125
            :||   :...|. |.:...:..:.:.|:.||...||.::..|||:.|||..::||.:...:.||:
  Rat    77 LLG---EIRGHW-LDKLRREWQMERAFQTALWLLQPEVVFILGDVFDEGKWSSAQAWADDLHRFQ 137

  Fly   126 RIYQNKNYKKFRMISAFFQRVHVPGDNDIGGENGDYISNSNQRRFENEFMSEDLFDYDNRLRFFK 190
            |::::.::.:.::         |.|::|||...  .:|.....|||..|.||.||.... :.|..
  Rat   138 RMFRHGSHVQLKV---------VIGNHDIGFHY--QMSKYRINRFEKVFGSERLFSLKG-VNFVM 190

  Fly   191 INRMLL-------------DFSNPDRDNNADRLRI-GVSH----------APLLIGGGPLLRAII 231
            :|.:.:             :.....|..|..:.:: |.|.          ||:|:...||.||
  Rat   191 VNSVAMEGDGCTICSEAEAELREISRKLNCSQEQVQGSSQCDHEPRLPLSAPVLLQHYPLYRA-- 253

  Fly   232 SD------------------------------------LDPHIIFSGHWHESRIFIYPSTKVINF 260
            ||                                    |.|.:|.|||.|.:...::|.
  Rat   254 SDANCSGEDAAPPEERSVPFEEKYDVLSREASQKLLWWLRPRLILSGHTHSACEVLHPG------ 312

  Fly   261 YENSVRHFDLKALKEQEHSYLEIMVPTCSYR-MGKSKIGLGYAVLENYNLSYTVLWQPNRFILLF 324
                              ...|:.||:.|:| .......:|.....:|.||...|  |....:|.
  Rat   313 ------------------GAPEVSVPSFSWRNRNNPSFIMGSLTSRDYALSKCYL--PCEDTVLT 357

  Fly   325 TYVFWGLFVV 334
            ||.....|::
  Rat   358 TYCAAAAFLL 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mppe	NP_001286327.1	Metallophos	52..246	CDD:278574	57/253 (23%)
Mppe	NP_001286327.1	MPP_Cdc1_like_1	54..293	CDD:277373	64/299 (21%)
Mppe1	NP_001101905.1	Metallophos	67..303	CDD:278574	57/253 (23%)
Mppe1	NP_001101905.1	MPP_MPPE1	70..327	CDD:277372	64/298 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3662
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094620at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820