DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mppe and SPAC630.12

DIOPT Version :9

Sequence 1:	NP_001286327.1	Gene:	Mppe / 36285	FlyBaseID:	FBgn0259985	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_592908.1	Gene:	SPAC630.12 / 2543429	PomBaseID:	SPAC630.12	Length:	422	Species:	Schizosaccharomyces pombe

Alignment Length:	405	Identity:	85/405 - (20%)
Similarity:	163/405 - (40%)	Gaps:	108/405 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LLLVFFNEFIVY--------------YMAQSSWQPIDCKLDNCTRLLLIADPQILGN-SYDRSSH 71
            |:::.|..:::|              :.:...|:    ...|..|:.|:||||::.: :||..
pombe     7 LVIIAFCFYVLYLEKIIHTRPHKKCDWRSWEQWE----STGNPVRIALVADPQLVDDLTYDYP-- 65

  Fly    72 SPL---ARYDSDRYLAKTFERALAFTQPHIIVFLGDLLDEGNIATAQEYKQYVQRFRRIYQNKNY 133
            .||   .::.||::|.:.:.......:|.|...:|||:|.|.....:|:|            |:|
pombe    66 RPLIGIVKWISDQFLRRHWRYLHKSLKPDITFIMGDLMDTGREFATEEFK------------KDY 118

  Fly   134 KKFRMISA----FFQRVHV-PGDNDIGGENGDYISNSNQRRFENEF----MSEDLFDY------- 182
              |||::.    |..::.: ||::|||  .|::....:.:|||:.|    .|.|:.::
pombe   119 --FRMMNVLDPKFTNKLEIYPGNHDIG--FGNHAIVKDIQRFESLFGPTSRSIDVGNHTLVIVDG 179

  Fly   183 ---DNRL--RFFKINRMLLDFSNPDRDNNADRLRIGVSHAPLLIGGGPLLRAI--ISDLDPHIIF 240
               .|.:  :.::..|..|.....::||:  |.||.:||.||.   .|.:.:.  :.:.|..|.:
pombe   180 IRLSNNVNPQVYQPARDFLKSFETNKDNS--RPRILLSHVPLF---RPAINSCGELREKDDVIKY 239

  Fly   241 S-GHWHESRIFIYPSTKVINFYENSVRHFDLKALKEQEHSYLEIM---------VPTCSYR---- 291
            . |:.:::.:....|..::...|      .:.|....:|.|.|::         ..|..|.
pombe   240 GLGYQYQNLLLPELSESILKAVE------PIAAFAGDDHDYCEVVHNYQVDTREAATTEYNVKAF 298

  Fly   292 -MGKSKIGLGYAVL--------------ENYNLSYTVLWQPNRFILLFTYVFWGLFVVCGFVVFK 341
             |....:..||.:|              .:|.....:|  ||:..:   ||::|..:...|.:..
pombe   299 SMTSGILYPGYQLLSLNYPYDNPKADQKSSYQTKLCIL--PNQIQI---YVWYGASISIFFALIL 358

  Fly   342 MMTRCPFRVAKRQTL 356
            :.|...|....|.:|
pombe   359 LRTAIFFFGTDRYSL 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mppe	NP_001286327.1	Metallophos	52..246	CDD:278574	56/221 (25%)
Mppe	NP_001286327.1	MPP_Cdc1_like_1	54..293	CDD:277373	63/280 (23%)
SPAC630.12	NP_592908.1	MPP_Cdc1	49..303	CDD:277370	64/282 (23%)
SPAC630.12	NP_592908.1	Metallophos	80..241	CDD:278574	43/181 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3662
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13315
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1923
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940