DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otk2 and zgc:171470

DIOPT Version :9

Sequence 1:	NP_612571.1	Gene:	otk2 / 36284	FlyBaseID:	FBgn0267728	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001104655.1	Gene:	zgc:171470 / 565848	ZFINID:	ZDB-GENE-080204-4	Length:	374	Species:	Danio rerio

Alignment Length:	345	Identity:	73/345 - (21%)
Similarity:	127/345 - (36%)	Gaps:	60/345 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LIFCSYAAPASFEDVSISRGPKSSITIKEQSSLQLPCDYQLPDGYLQKSSVILRWRKDSKTLRQV 83
            |||.......|..|.:::.. .|.|...:.||:.:.|.::.|.|: |...|.  |.||....|.
Zfish    11 LIFLLMIHMVSSADWAVTYS-SSHICALKDSSVIMSCTFKYPTGH-QIMKVF--WNKDFVEHRD- 70

  Fly    84 ELGRMDSTTSEPQLETML------REDSRVALS----KDSGALQFTSVLASDAGQYQCQLVIDDS 138
            ||..:   :..|:....|      :::..|.||    ||.....|..:.....|::
Zfish    71 ELADL---SEHPEYSQRLQYLGDKQQNCTVKLSLVTKKDEHMYYFRFITDQPGGKW--------- 123

  Fly   139 VAASSSSGVLLVIEQLKFVPQPTSKNLELGTLSKVHCKAQG--TPAPQVKWMRETQLPLPVNVTD 201
               :...||.|.:..|:.   .:.:.:..|...::.|::..  |..|...|.|.::     .:.:
Zfish   124 ---AGYPGVRLSVTDLQL---ESPERVTEGDSVRLTCRSSCNLTDTPTFIWYRNSE-----RMIE 177

  Fly   202 QNGTLIFNQVSNEQRGQYTCIASNSQGQITATVSINVVVAPK-FSVPPEGPIEVAEAGTAVIHCQ 265
            ::..|:.:.|..|..|:|.| |.:.....:..:.:||:..|| .||...|...:....:..::|.
Zfish   178 RSSELLLHSVRREDAGRYRC-AVHGHTLTSPEIYLNVMYPPKSVSVSISGSAVIVSGDSVTLNCS 241

  Fly   266 AIGEPKPTIQWDKDLTYLNENNTDPERFSLMENGTLEIRNVRPEDEGRYGCTIGSSAGLKREDVL 330
            :...|...|.|.|..|            |:.......|..:...|.|.|.|...::.|.|..|.:
Zfish   242 SDSNPPAEISWFKGET------------SVGSGRIFNISKISSGDSGEYKCRARNALGEKYSDPV 294

  Fly   331 LV------LKSSKSASNSIV 344
            .:      :..|.|.|.|.|
Zfish   295 TLDVQYPPMNVSVSISGSAV 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otk2	NP_612571.1	IG_like	41..132	CDD:214653	24/100 (24%)
		I-set	155..238	CDD:254352	13/84 (15%)
		IGc2	175..228	CDD:197706	12/54 (22%)
		IG_like	250..331	CDD:214653	16/80 (20%)
		IGc2	258..323	CDD:197706	12/64 (19%)
zgc:171470	NP_001104655.1	Ig	25..114	CDD:299845	23/96 (24%)
		IG_like	140..213	CDD:214653	13/78 (17%)
		Ig_2	140..>197	CDD:290606	11/61 (18%)
		Ig_2	224..298	CDD:290606	16/85 (19%)
		IG_like	225..298	CDD:214653	16/84 (19%)
		IG_like	310..373	CDD:214653	3/5 (60%)
		Ig_2	314..373	CDD:290606	1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4475
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900