DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otk2 and ptk7a

DIOPT Version :9

Sequence 1:	NP_612571.1	Gene:	otk2 / 36284	FlyBaseID:	FBgn0267728	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001018501.1	Gene:	ptk7a / 553690	ZFINID:	ZDB-GENE-050522-216	Length:	231	Species:	Danio rerio

Alignment Length:	207	Identity:	53/207 - (25%)
Similarity:	85/207 - (41%)	Gaps:	35/207 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 SSSSGVLLVI-----------EQLKFVPQPTSKNLELGTLSKVHCKAQGTPAPQVKWMRETQLPL 195
            :|:..|||.:           ....|...|.|::...|..:.:.|:..........|::..:
Zfish    13 ASAENVLLALTLIGEVIMAQAASFYFTKAPKSQDALHGRSAMLRCEVNDPQGVSYAWIQNGE--- 74

  Fly   196 PVNVTDQ----NGTLIFNQVSNE-QRGQYTCIAS-NSQG--QITATVSINVVVAPKFSV---PPE 249
            ||..:::    .|.|.|..:... ..|.:.|||| ||.|  :.||..|.|:......:|   .||
Zfish    75 PVTNSERRFLDGGNLKFTAIDRTLDSGNFQCIASKNSTGEEERTAETSFNIKWLESGAVSLKSPE 139

  Fly   250 GPIEVAEAGTAVIHCQAIGEPKPTIQWDKDLTYLNENN---TDPERFSLMENGTLEIRNVRPEDE 311
            ...|:..:...::.|...|.|:||.:|.||.|.:.|.|   .:.||       :|.:.|..|:|.
Zfish   140 SVAEIQSSSQVILRCNIDGHPRPTNRWFKDGTQITEKNYKINNKER-------SLTLPNASPDDN 197

  Fly   312 GRYGCTIGSSAG 323
            |.|.|...::||
Zfish   198 GLYFCCAKNAAG 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otk2	NP_612571.1	IG_like	41..132	CDD:214653
		I-set	155..238	CDD:254352	22/90 (24%)
		IGc2	175..228	CDD:197706	14/58 (24%)
		IG_like	250..331	CDD:214653	23/77 (30%)
		IGc2	258..323	CDD:197706	20/67 (30%)
ptk7a	NP_001018501.1	I-set	37..120	CDD:254352	20/85 (24%)
		Ig	42..122	CDD:299845	20/82 (24%)
		Ig	150..222	CDD:299845	22/67 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580766
Domainoid	1	1.000	69	1.000	Domainoid score	I9605
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245153at33208
OrthoFinder	1	1.000	-	-		FOG0007317
OrthoInspector	1	1.000	-	-		otm26203
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.850