DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otk2 and Ror

DIOPT Version :9

Sequence 1:	NP_612571.1	Gene:	otk2 / 36284	FlyBaseID:	FBgn0267728	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_476962.1	Gene:	Ror / 34367	FlyBaseID:	FBgn0010407	Length:	685	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	61/327 - (18%)
Similarity:	120/327 - (36%)	Gaps:	73/327 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 YAAPA-SFEDVSISRGPKSSITIKEQSSLQLPCDYQLPDGYLQKSSVILRWRKDSKTLRQVELGR 87
            ||.|: .|..:.|.|.|       |:::|....:.......|:..| |.|.|..||.::.:.:.:
  Fly    93 YALPSLCFSSMPICRTP-------ERTNLLYFANVATNAKQLKNVS-IRRKRTKSKDIKNISIFK 149

  Fly    88 MDSTTSEPQLETMLREDSRVALSKDSGALQFTSVLASDAGQYQCQLVIDD------SVAASSSSG 146
            ..||..|....|.:  .|:...:::|..|:...       :.:|:|:.::      ::|......
  Fly   150 KKSTIYEDVFSTDI--SSKYPPTRESENLKRIC-------REECELLENELCQKEYAIAKRHPVI 205

  Fly   147 VLLVIEQLKFVPQPTSKN-LELGTLSKV----HC--------------KAQGTPAPQVKWMRETQ 192
            .::.:|..:.:||  .|: |.||...:|    :|              .|.|.|..:..|:.:..
  Fly   206 GMVGVEDCQKLPQ--HKDCLSLGITIEVDKTENCYWEDGSTYRGVANVSASGKPCLRWSWLMKEI 268

  Fly   193 LPLPVNVTDQNGTLIFNQVSNEQRGQYTCIASNSQGQITATVSINVVVAPKFSVPPEGPIEVAEA 257
            ...| .:..||.......|.|..    .|...:|:.:|     |.:...||.:    ..|.:|..
  Fly   269 SDFP-ELIGQNYCRNPGSVENSP----WCFVDSSRERI-----IELCDIPKCA----DKIWIAIV 319

  Fly   258 GTA--------VIHCQAIGEPKPTIQWD-KDLTYLNENNTDPERFSLMENGTLEIRNVRPEDEGR 313
            ||.        :|....:.:.:..:.:. :::..:|..:.|...:     |..::.|.:....|.
  Fly   320 GTTAAIILIFIIIFAIILFKRRTIMHYGMRNIHNINTPSADKNIY-----GNSQLNNAQDAGRGN 379

  Fly   314 YG 315
            .|
  Fly   380 LG 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otk2	NP_612571.1	IG_like	41..132	CDD:214653	16/90 (18%)
		I-set	155..238	CDD:254352	21/101 (21%)
		IGc2	175..228	CDD:197706	12/66 (18%)
		IG_like	250..331	CDD:214653	11/75 (15%)
		IGc2	258..323	CDD:197706	9/67 (13%)
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568	33/153 (22%)
		KR	235..312	CDD:214527	16/90 (18%)
		PTKc_Ror	404..673	CDD:270642
		Pkinase_Tyr	410..670	CDD:285015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910