DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otk2 and F11r

DIOPT Version :9

Sequence 1:	NP_612571.1	Gene:	otk2 / 36284	FlyBaseID:	FBgn0267728	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_446248.1	Gene:	F11r / 116479	RGDID:	621842	Length:	300	Species:	Rattus norvegicus

Alignment Length:	234	Identity:	58/234 - (24%)
Similarity:	92/234 - (39%)	Gaps:	48/234 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 KVHCKAQGTPAPQVKWM-------------RETQLPLPVNVTDQNGTLIFNQVSNEQRGQYTCIA 223
            |:.|...|..:|:|:|.             .:..:|....||..:..:.|:.|:.:..|:|||:.
  Rat    46 KLPCIYSGFSSPRVEWKFVQGSTTALVCYNNQITVPYADRVTFSSSGITFSSVTRKDNGEYTCMV 110

  Fly   224 SNSQGQITATVSINVVVAPKFSVPPEGPI-----EVAEAGTAVIHC-QAIGEPKPTIQWDKD--- 279
            |...||....|||::.|.    |||..|.     .|.....||:.| :..|.|.....|.||
  Rat   111 SEDGGQNYGEVSIHLTVL----VPPSKPTVSIPSSVTIGNRAVLTCSEHDGSPPSEYSWFKDGVP 171

  Fly   280 -LT--------YLNENNT-DPERFSLMENGTLEIRNVRPEDEGRYGCTIGSSAGLKREDVLLVLK 334
             ||        ::|.:.| ||      ::|.|....|...|.|.|.|...:..|.......:.::
  Rat   172 MLTADAKKTRAFINSSYTIDP------KSGDLVFDPVSAFDSGEYYCEAQNGYGTAMRSEAVRME 230

  Fly   335 SSKSASNSIVTRIIIVIICLAFLYFVLVLGLKVWYRYRR 373
            :.:.....||..:::.:|.|..|.|      .:|:.|.|
  Rat   231 AVELNVGGIVAAVLVTLILLGLLIF------GIWFAYSR 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otk2	NP_612571.1	IG_like	41..132	CDD:214653
		I-set	155..238	CDD:254352	21/78 (27%)
		IGc2	175..228	CDD:197706	15/65 (23%)
		IG_like	250..331	CDD:214653	24/99 (24%)
		IGc2	258..323	CDD:197706	21/78 (27%)
F11r	NP_446248.1	V-set	33..128	CDD:284989	21/81 (26%)
		IG_like	37..127	CDD:214653	21/80 (26%)
		Ig	139..229	CDD:299845	23/95 (24%)
		IG_like	141..221	CDD:214653	23/85 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000