DRSC/TRiP Functional Genomics Resources

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Protein Alignment otk2 and mag

DIOPT Version :9

Sequence 1:NP_612571.1 Gene:otk2 / 36284 FlyBaseID:FBgn0267728 Length:433 Species:Drosophila melanogaster
Sequence 2:XP_004916459.1 Gene:mag / 100494147 XenbaseID:XB-GENE-6462484 Length:625 Species:Xenopus tropicalis


Alignment Length:438 Identity:86/438 - (19%)
Similarity:137/438 - (31%) Gaps:145/438 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 FEDVSISRG-----PKSSITIKEQSSLQLPCDYQLPD---------------------------- 61
            |.|.::||.     |: ||:....:.:.:||.:..|:                            
 Frog    14 FTDGALSRQWAAWMPQ-SISAFRDTCVAIPCSFDYPNDIRPSVIHGIWYFNSPYPKNFPPVVLKT 77

  Fly    62 ----------------GYLQKSSVILRWRKDSKTLR-----QVELGRMDSTTSEPQLETMLREDS 105
                            |.:|:|:..|:..:.|..|:     :|:||..:..|........:.::.
 Frog    78 KTNTAHDNYMGRTKLLGDIQESNCTLQIDRLSMDLQGKYYFRVDLGGYNQYTYSEHANLYMLDEP 142

  Fly   106 RVALSKDSGALQFTSVLASDAGQYQCQLVIDD-------------------SVAAS--SSSGVLL 149
            .|:|.::        :::....:..|: |.|:                   ||..|  .|.....
 Frog   143 FVSLPQE--------MVSGSEAELTCR-VPDNCPDMKPSVNWMEIEGLEHHSVYGSLEESRSTWT 198

  Fly   150 VIEQLKFVPQPTSKNLEL--------------------------------------GTLSKVHCK 176
            .:..|||:|...:....|                                      ||.....|.
 Frog   199 QVSTLKFIPSYKNNGQRLSCKVSFPGADMEYKGFVTMNVKYAPRIVDINSSFETTEGTQVVFVCV 263

  Fly   177 AQGTPAPQVKWMRETQLPLPVNVTDQNGTLIFNQVSNEQRGQYTCIASNSQGQITATVSINVVVA 241
            ....|..:|.|.:|..| :..:||. |.||....|:....|.|.|.|.|..|:...|:.:.|:..
 Frog   264 VDSNPVSRVGWYKEGAL-IREDVTG-NLTLELEYVTFNHDGIYVCAAENEYGRTNKTMGLAVMYP 326

  Fly   242 P-KFSVPPEGPIEVAEAGTAVIHCQAIGEPKPTIQWDKDLTYLNENNTDPERFSLMEN-GTLEIR 304
            | |.||  ...:...|..|..|.|...|.|.|.|...||...|..        .:.|| ...||.
 Frog   327 PWKPSV--NASVTAMEGETITILCNTQGNPDPIISIVKDKQVLTS--------VIFENEAVFEIP 381

  Fly   305 NVRPEDEGRYGCTIGSSAGLKREDV--------LLVLKSSKSASNSIV 344
            .:..|.:|.|.||..:..|......        |::|:|..:.|...|
 Frog   382 AITHEHDGEYWCTAENQYGQSNSSFNLTVVFSPLVLLESKCTVSKDTV 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
otk2NP_612571.1 IG_like 41..132 CDD:214653 17/139 (12%)
I-set 155..238 CDD:254352 25/120 (21%)
IGc2 175..228 CDD:197706 17/52 (33%)
IG_like 250..331 CDD:214653 21/89 (24%)
IGc2 258..323 CDD:197706 19/65 (29%)
magXP_004916459.1 Ig 23..131 CDD:416386 16/108 (15%)
FR1 23..47 CDD:409353 5/24 (21%)
Ig strand A 23..27 CDD:409353 0/3 (0%)
Ig strand A' 30..34 CDD:409353 2/3 (67%)
Ig strand B 36..47 CDD:409353 2/10 (20%)
CDR1 48..55 CDD:409353 1/6 (17%)
FR2 56..63 CDD:409353 0/6 (0%)
Ig strand C 56..63 CDD:409353 0/6 (0%)
CDR2 64..87 CDD:409353 0/22 (0%)
Ig strand C' 74..77 CDD:409353 0/2 (0%)
FR3 88..121 CDD:409353 6/32 (19%)
Ig strand D 89..93 CDD:409353 0/3 (0%)
Ig strand E 99..107 CDD:409353 2/7 (29%)
Ig strand F 114..122 CDD:409353 1/7 (14%)
CDR3 122..126 CDD:409353 2/3 (67%)
Ig 142..236 CDD:416386 14/102 (14%)
Ig strand A 142..146 CDD:409353 1/3 (33%)
Ig strand B 155..161 CDD:409353 0/5 (0%)
Ig strand C 172..177 CDD:409353 0/4 (0%)
Ig strand E 201..207 CDD:409353 3/5 (60%)
Ig strand F 214..221 CDD:409353 1/6 (17%)
Ig strand G 228..236 CDD:409353 0/7 (0%)
Ig_3 241..310 CDD:404760 18/70 (26%)
Ig strand B 258..262 CDD:409353 0/3 (0%)
Ig strand C 271..275 CDD:409353 1/3 (33%)
Ig strand E 289..293 CDD:409353 2/3 (67%)
Ig strand F 303..308 CDD:409353 2/4 (50%)
IG 335..410 CDD:214652 21/82 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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