DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment otk and AT5G61350

DIOPT Version :9

Sequence 1:	NP_523705.2	Gene:	otk / 36283	FlyBaseID:	FBgn0004839	Length:	1033	Species:	Drosophila melanogaster
Sequence 2:	NP_200943.1	Gene:	AT5G61350 / 836256	AraportID:	AT5G61350	Length:	842	Species:	Arabidopsis thaliana

Alignment Length:	817	Identity:	158/817 - (19%)
Similarity:	282/817 - (34%)	Gaps:	274/817 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 HSFDSG-------KDALLREDARLVLHKQNGTLSFASIIASDAGQYQCQLQLEAHAPINSSPGI- 370
            |.|.:|       |:.|:....:|.|:.:....|.|.|.|.:......:|..::.:.:..:|..
plant   142 HDFSAGDTSSIVFKEYLIYAAEKLSLYFKPHKGSTAFINAVEIVSVPDELVPDSASSVPQAPDFK 206

  Fly   371 ------LEVIEQLKFVPQPTSKNLELDAVVAKVHCKAQGTPTPQVQWVRDGENTTLPD---HVEV 426
                  ||::.::         |:..|.:..|:      .|..:. |:.|....|.|:   :|.|
plant   207 GLSSFSLEILHRI---------NIGGDLISPKI------DPLSRT-WLSDKPYNTFPEGSRNVTV 255

  Fly   427 DANGTLIFRNVNSEHRGNYTCL---------------ATNSQGQINATVAINV------------ 464
            |.: |:.:.:      |..|.|               |..||...|.:..::|
plant   256 DPS-TITYPD------GGATALIAPNPVYATAEEMADAQTSQPNFNLSWRMSVDFGHDYFIRLHF 313

  Fly   465 --VVTPKFS----------VPPVGPIE----TSEQGTV-----VMHCQAIGD--------PKPTI 500
              :|:...:          :..:..::    ||..||.     |::...|.:        |.|.:
plant   314 CDIVSKSLNDLIFNVFINKLSAISALDLSSLTSALGTAYYADFVLNASTITNGSILVQVGPTPNL 378

  Fly   501 QWDK------DLKYLSENNTDRERFRFLENGTLE-IRNVQVEDEGSYGCTIGNSAGLKREDVQLV 558
            |..|      .|:.:..||.         .|:|: :..|    :|.|...||..:..|
plant   379 QSGKPNAILNGLEIMKLNNA---------AGSLDGLFGV----DGKYKGPIGGMSSKK------- 423

  Fly   559 VKTTGDGFAPEESGGDGFLVTRAVLITMTVALAYIVLVVGLMLWCRYRRQARK-ARLNDLSTKEA 622
            :...|.||                ::.:|..|..:||:|      |::|:.:. .:.|..|:
plant   424 LAIAGIGF----------------VMALTAFLGVVVLLV------RWQRRPKDWQKQNSFSS--- 463

  Fly   623 GGDQPDVAGNGKGSEQEPCLSKQHNGHSKSRSKSSGDAQKSDDTACSQQSRASKKSAHI------ 681
                              .|...|..||...|...|...:......|::|:::..|:..
plant   464 ------------------WLLPLHASHSSYISSKGGSTSRRMSIFGSKKSKSNGFSSFFSNQGLG 510

  Fly   682 ----YEQLALPRSGLSELIQIGRGEFGDVFVGKLKATLVTSPSDKDADTEKQHSNSENGSGGSGS 742
                :.:|........|....|.|.||.|::|::                              .
plant   511 RYFPFTELQTATQNFDENAVCGVGGFGKVYIGEI------------------------------D 545

  Fly   743 GSTTLSTLNEKRRSKTSMDDIEEIKEEEQDQHNQSGLEQLVLVKALNKVKDEQACQEFRRQLDLL 807
            |.|.::.   ||.|::|                                  ||...||:.::.:|
plant   546 GGTQVAI---KRGSQSS----------------------------------EQGINEFQTEIQML 573

  Fly   808 RAISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQFLLATAGKVNTATAGSSSPPPLTT---SQV 869
            ..:.|:.:|.|.|.|.|.....:|.||...|.|:..|..:.         .:.|.|:.|   .|.
plant   574 SKLRHRHLVSLIGFCDENKEMILVYEYMSNGPLRDHLYGSK---------ENDPNPIPTLSWKQR 629

  Fly   870 LAVAYQIARGMDAIYRAR---FTHRDLATRNCVISSEFIVKVSYPALCKDKYSREYHKHRNTLLP 931
            |.:....|||:..::...   ..|||:.|.|.::....:.|||...|.||....|.|........
plant   630 LEICIGSARGLHYLHTGAAQGIIHRDVKTTNILLDENLVAKVSDFGLSKDAPMDEGHVSTAVKGS 694

  Fly   932 IRWLAPECIQEDEYTTKSDIFAYGVVVWELFNQATKLPHEELTNEQVVQRSQAGSLEWSVAEATP 996
            ..:|.||..:..:.|.|||::::|||::|:. .|..:.:.:|..|||           ::||...
plant   695 FGYLDPEYFRRQQLTDKSDVYSFGVVLFEVL-CARPVINPQLPREQV-----------NLAEYAM 747

  Fly   997 DSLREILLSCWVSNPKERPSFSQLGAALSKAMQSAEK 1033
            :..|:.:|. .:.:||...:.|:  .:|.|.:::|||
plant   748 NLHRKGMLE-KIIDPKIVGTISK--GSLRKFVEAAEK 781

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otk	NP_523705.2	I-set	26..115	CDD:254352
		Ig	31..115	CDD:299845
		IGc2	133..195	CDD:197706
		Ig	268..373	CDD:299845	14/72 (19%)
		Ig	395..460	CDD:143165	17/82 (21%)
		I-set	468..559	CDD:254352	21/124 (17%)
		IGc2	484..549	CDD:197706	18/84 (21%)
		PTK_CCK4	686..1026	CDD:133178	75/345 (22%)
		STYKc	692..1020	CDD:214568	74/333 (22%)
AT5G61350	NP_200943.1	Malectin_like	36..394	CDD:403886	47/274 (17%)
AT5G61350	NP_200943.1	STKc_IRAK	532..801	CDD:270968	78/341 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I2197
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050