DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment otk and AT5G48740

DIOPT Version :9

Sequence 1:	NP_523705.2	Gene:	otk / 36283	FlyBaseID:	FBgn0004839	Length:	1033	Species:	Drosophila melanogaster
Sequence 2:	NP_199685.2	Gene:	AT5G48740 / 834932	AraportID:	AT5G48740	Length:	895	Species:	Arabidopsis thaliana

Alignment Length:	1089	Identity:	201/1089 - (18%)
Similarity:	339/1089 - (31%)	Gaps:	390/1089 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 IYLESASVQLLGSNRNELLLKCHVEGASGDLEPLEIEWYRNSEKLSTWKNVQL------DQHRLI 174
            :.|.|..|....|....|.|.|   |.|.......|.|..:::.:.|.....:      ....:.
plant     5 VLLSSFCVFCFSSPDGFLSLSC---GGSSYTAAYNISWVSDNDYIETGNTTTVTYAEGNSTSSVP 66

  Fly   175 IRQ-PGSEDDGLYRCTASNAAGRVMSKQGYVYQSSVKCLPRLPRRKNEKMMESWDKQT-----FL 233
            ||. |..:....|:.........|:.:..:||:                   ::|.|.     .:
plant    67 IRLFPDPQGRQCYKLPVRKDLSSVLIRATFVYR-------------------NYDSQNSPPAFHV 112

  Fly   234 CRGKRGGAAGLEALPAAPEDLRIVQGPIGQSIIKEGEPTALTCLYELPDELKNQRIQLRWRKDGK 298
            ..|:|         ..:..|||.....|.:.:......:.|.||.    .:|.:.|        .
plant   113 SLGRR---------ITSTVDLRTNDPWIEELVWPVNNDSLLLCLL----AVKGRGI--------P 156

  Fly   299 LLRQVELGGSAPIP----GHSFDSGKDALLREDARLVLHKQNGTLSFAS-----IIASDAGQYQC 354
            ::..:|:   .|:|    .:|.:...|.:||...|:.....|||:.:.|     |...|
plant   157 VISSLEV---RPLPLGSYKYSLEGSPDIILRRSYRINSGYTNGTIRYPSDPFDRIWDPD------ 212

  Fly   355 QLQLEAHAPINSSPGI--LEVIEQLKFVPQPTSKNLELDAVVAKVHCKAQGTPTPQVQWVRDGEN 417
                ::::|.::|...  |..:........|.:..|:...::|:                ::..:
plant   213 ----QSYSPFHASWSFNGLTKLNSFNITENPPASVLKTARILAR----------------KESLS 257

  Fly   418 TTLPDHVEVDANGTLIFR-----------NVNSE-HRGNYTCLATNSQ-----------GQINAT 459
            .||..|...|....|.|.           .:|.| .:.:||  .|:|:           .::|.|
plant   258 YTLSLHTPGDYYIILYFAGILSLSPSFSVTINDEVKQSDYT--VTSSEAGTLYFTQKGISKLNIT 320

  Fly   460 V----------AINVV----VTPKFSVPPVGPIETSEQGTVVMHCQAIG---DPKPTIQWDK--- 504
            :          |:.|.    :.|:.|...|..::..||.|    .|.:|   ||...:.|:.
plant   321 LRKIKFNPQVSALEVYEILQIPPEASSTTVSALKVIEQFT----GQDLGWQDDPCTPLPWNHIEC 381

  Fly   505 --------------------------DLKYLSENNTDRERFRFLENGTLEIRNV----------- 532
                                      |||.|..:||..         |..|:||
plant   382 EGNRVTSLFLSKINLRSISPTFGDLLDLKTLDLHNTSL---------TGAIQNVGSLKDLQKLNL 437

  Fly   533 ---QVEDEGSYGCTIGNSAGLKREDVQLVVKTTGDGFAPEESGGDGFLVTRAVLITMTVALAYIV 594
               |:|   |:|..:.:...|:..|:|   ..:..|..||..|
plant   438 SFNQLE---SFGSELEDLVNLEVLDLQ---NNSLQGSVPETLG---------------------- 474

  Fly   595 LVVGLMLWCRYRRQARKARLNDLSTKEAGGDQPD----------VAGNGKGSEQEPCLS----KQ 645
                         :.:|.||.:|......|..|.          :.||       ||||    ..
plant   475 -------------KLKKLRLLNLENNNLVGPLPQSLNITGLEVRITGN-------PCLSFSSISC 519

  Fly   646 HNGHS-------------KSRSKS--------SGDA-------------------QKSDDTACSQ 670
            :|..|             |.|.::        ||.|                   .|..|...:|
plant   520 NNVSSTIDTPQVTIPINKKQRKQNRIAILLGVSGGALFATFLVFVFMSIFTRRQRNKERDITRAQ 584

  Fly   671 QSRASKKSAHIYEQLALPRSGLSELIQIGRGEFGDVFVGKLKATLVTSPSDKDADTEKQHSNSEN 735
            ....:..::.|:....:..:..:....||||.||.|:.|||       |..|....:.:...::.
plant   585 LKMQNWNASRIFSHKEIKSATRNFKEVIGRGSFGAVYRGKL-------PDGKQVAVKVRFDRTQL 642

  Fly   736 GSGGSGSGSTTLSTLNEKRRSKTSMDDIEEIKEEEQDQHNQSGLEQLVLVKALNKVKDEQACQEF 800
            |:                                                            ..|
plant   643 GA------------------------------------------------------------DSF 647

  Fly   801 RRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQFLLATAGKVNTATAGSSSPPPLT 865
            ..::.||..|.|:.:|...|.|.|.....:|.||...|.|...|.....|.::          |.
plant   648 INEVHLLSQIRHQNLVSFEGFCYEPKRQILVYEYLSGGSLADHLYGPRSKRHS----------LN 702

  Fly   866 TSQVLAVAYQIARGMDAIYRA---RFTHRDLATRNCVISSEFIVKVSYPALCKDKYSREYHKHRN 927
            ....|.||...|:|:|.::..   |..|||:.:.|.::..:...|||...|.| ::::....|..
plant   703 WVSRLKVAVDAAKGLDYLHNGSEPRIIHRDVKSSNILLDKDMNAKVSDFGLSK-QFTKADASHIT 766

  Fly   928 TLL--PIRWLAPECIQEDEYTTKSDIFAYGVVVWELFNQATKLPHE---ELTNEQVVQRS--QAG 985
            |::  ...:|.||.....:.|.|||::::|||:.||......|.|.   :..|..:..|.  |||
plant   767 TVVKGTAGYLDPEYYSTLQLTEKSDVYSFGVVLLELICGREPLSHSGSPDSFNLVLWARPNLQAG 831

  Fly   986 SLEW--SVAEAT--PDSLRE---ILLSCWVSNPKERPSFSQLGAALSKA 1027
            :.|.  .:.:.|  |.|:::   |.:.|...:...|||.:::...|.:|
plant   832 AFEIVDDILKETFDPASMKKAASIAIRCVGRDASGRPSIAEVLTKLKEA 880

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otk	NP_523705.2	I-set	26..115	CDD:254352
		Ig	31..115	CDD:299845
		IGc2	133..195	CDD:197706	12/68 (18%)
		Ig	268..373	CDD:299845	22/115 (19%)
		Ig	395..460	CDD:143165	14/87 (16%)
		I-set	468..559	CDD:254352	28/136 (21%)
		IGc2	484..549	CDD:197706	20/110 (18%)
		PTK_CCK4	686..1026	CDD:133178	77/356 (22%)
		STYKc	692..1020	CDD:214568	76/344 (22%)
AT5G48740	NP_199685.2	Malectin_like	24..338	CDD:403886	63/387 (16%)
AT5G48740	NP_199685.2	STKc_IRAK	612..879	CDD:270968	77/344 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I2197
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050