DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment otk and AT5G39000

DIOPT Version :9

Sequence 1:	NP_523705.2	Gene:	otk / 36283	FlyBaseID:	FBgn0004839	Length:	1033	Species:	Drosophila melanogaster
Sequence 2:	NP_198716.1	Gene:	AT5G39000 / 833892	AraportID:	AT5G39000	Length:	873	Species:	Arabidopsis thaliana

Alignment Length:	930	Identity:	193/930 - (20%)
Similarity:	320/930 - (34%)	Gaps:	293/930 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   256 IVQGPI-GQSIIKEGEPTALTCLYELPD------------ELKNQRI------------QLRWRK 295
            :|..|| |:......|||.: .|:...|            ..:||:|            |..:::
plant    12 LVSTPIVGEGATSTYEPTDV-FLFNCGDTSNNVDVSGRNWTAENQKILSSNLVNASFTAQASYQE 75

  Fly   296 DG---------KLLRQVELGGSAPI-PGHSFDSGKDALLREDARLVLH------KQNGTLSFASI 344
            .|         ::.|. |...|.|: ||.:|           .||..:      :.|...||.|:
plant    76 SGVSQIPYMTARIFRS-EFTYSFPVTPGSNF-----------LRLYFYPTRYGSQFNAVKSFFSV 128

  Fly   345 IASD---AGQYQCQLQLEAHAPINSSPGILEVIEQLKFVPQ----PTSKNLELDAVVAKVHCKAQ 402
            ..:.   ...:...|.::|..|            |.:|:.:    |..:.|.|
plant   129 KVNGFTLLNNFSADLTVKASKP------------QTEFIIKEFIIPVYQTLNL------------ 169

  Fly   403 GTPTPQVQ---WVRDGENTTLPDHVEVDANGTLIFRNVNSE---HRGNYTCLAT----------- 450
             |.||.:.   :|...|..::|:..........:..||.|.   |..|.|...|
plant   170 -TFTPSLDSLAFVNGIEIVSIPNRFYSKGGFDDVITNVGSSVDFHIENSTAFETVYRLNVGGKTV 233

  Fly   451 NSQGQINATVAIN-VVVTPKFSVPPVGP---IETSEQ-------GTVVMHCQAIGD---PKPTIQ 501
            ...|.....|:.: ::::....:.|:.|   |..:|:       ..|....:::|:   |:..:.
plant   234 GDSGMFRRWVSDDEIILSESSGISPIVPDIKINYTEKTPSYVAPDDVYATSRSMGNADHPEQNLN 298

  Fly   502 ----W----DKDLKY---------LSENNTDRERF--RFLEN--GTLEIRNVQVEDEGS------ 539
                |    |....|         |||.|.:.:|.  .|:||  .|||: :|.....||
plant   299 FNLTWLFTVDAGFSYLVRLHFCETLSEVNKEGQRVFSIFIENQTATLEM-DVFRMSGGSWIPMYL 362

  Fly   540 -YGCTIGNSAGLKREDVQLVVKTTGDGFAPEESGGDGFLVTRAVLITMTVALAYIVLVVGLMLWC 603
             |....|:.:| :|.|::|.:..                     |:::.... |..::.|:.:
plant   363 DYTVIAGSGSG-RRHDLRLDLHP---------------------LVSINPKY-YDAILNGVEI-- 402

  Fly   604 RYRRQARKARLNDLSTKEAGGDQPDVAGNGKGSEQEPCLSKQHNGHSKSRSKSSGDAQKSDDTAC 668
                    .::||          ||  ||..|...:|.:|                   .|....
plant   403 --------LKMND----------PD--GNLAGPNPDPLVS-------------------PDLIPN 428

  Fly   669 SQQSRASKKSAHIYEQLALPRSGLSELIQIGRGEFGDVFVGKLKATLVTSPSDKDADTEKQHSNS 733
            ....|..|..:||   |.:..:.:..|:.:.....|.:.:.|.|..  :.||...:.....|
plant   429 RATPRIRKNKSHI---LPITLAVVGSLVVLAMFVVGVLVIMKKKKK--SKPSTNSSWCPLPH--- 485

  Fly   734 ENGSGGSGSGSTTLSTLNEKRRSKTSMD-----DIEEIKEEEQDQHNQ----------------S 777
                   |:.||     |.|.......|     .|.|||....|..::                .
plant   486 -------GTDST-----NTKPAKSLPADLCRRFSIFEIKSATNDFEDKLIIGVGGFGSVYKGQID 538

  Fly   778 GLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQ 842
            |...||.||.| ::...|..:||..:|::|..:.|..:|.|.|.|.|.:...:|.||...|.||.
plant   539 GGATLVAVKRL-EITSNQGAKEFETELEMLSKLRHVHLVSLIGYCDEDNEMVLVYEYMPHGTLKD 602

  Fly   843 FLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYR-ARFT--HRDLATRNCVISSEF 904
            .|.         ....:|.|||:..:.|.:....|||:..::. |::|  |||:.|.|.::...|
plant   603 HLF---------RRDKTSDPPLSWKRRLEICIGAARGLQYLHTGAKYTIIHRDIKTTNILLDENF 658

  Fly   905 IVKVSYPALCKDKYSREYHKHRNTLL--PIRWLAPECIQEDEYTTKSDIFAYGVVVWELF----- 962
            :.|||...|.:...:.....|.:|::  ...:|.||..:....|.|||::::|||:.|:.
plant   659 VTKVSDFGLSRVGPTSASQTHVSTVVKGTFGYLDPEYYRRQVLTEKSDVYSFGVVLLEVLCCRPI 723

  Fly   963 -------NQA-----TKLPHEELTNEQVVQRSQAGSLEWSVAEATPDSLR---EILLSCWVSNPK 1012
                   .||     .|..:...|.:|::....:       |:.|..||.   ||.:.|......
plant   724 RMQSVPPEQADLIRWVKSNYRRGTVDQIIDSDLS-------ADITSTSLEKFCEIAVRCVQDRGM 781

  Fly  1013 ERPSFSQLGAALSKAMQSAE 1032
            |||..:.:..||..|:|..|
plant   782 ERPPMNDVVWALEFALQLHE 801

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otk	NP_523705.2	I-set	26..115	CDD:254352
		Ig	31..115	CDD:299845
		IGc2	133..195	CDD:197706
		Ig	268..373	CDD:299845	26/147 (18%)
		Ig	395..460	CDD:143165	14/81 (17%)
		I-set	468..559	CDD:254352	30/131 (23%)
		IGc2	484..549	CDD:197706	22/95 (23%)
		PTK_CCK4	686..1026	CDD:133178	92/385 (24%)
		STYKc	692..1020	CDD:214568	90/373 (24%)
AT5G39000	NP_198716.1	Malectin_like	35..405	CDD:372329	75/440 (17%)
AT5G39000	NP_198716.1	STKc_IRAK	524..794	CDD:270968	73/286 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I2197
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050