DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment otk and AT2G23200

DIOPT Version :9

Sequence 1:	NP_523705.2	Gene:	otk / 36283	FlyBaseID:	FBgn0004839	Length:	1033	Species:	Drosophila melanogaster
Sequence 2:	NP_179901.1	Gene:	AT2G23200 / 816852	AraportID:	AT2G23200	Length:	834	Species:	Arabidopsis thaliana

Alignment Length:	741	Identity:	163/741 - (21%)
Similarity:	261/741 - (35%)	Gaps:	251/741 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 PINSSPGILEVIEQLKF-----VPQPTSKNL----ELDAVVAKVHCKAQGTPTPQVQWVRDGE-- 416
            |.:||..::..||....     :|..:.|||    .|:....|:        ||      |.:
plant   174 PDHSSLALINAIEVFSAPDDLEIPSASDKNLHTIYRLNVGGEKI--------TP------DNDTL 224

  Fly   417 -NTTLPDHVEVDANGTLIF-----RNVNSEHRGNY------------------TCLATNSQGQIN 457
             .|.|||      :...::     ||:||....||                  |..|.|...  |
plant   225 GRTWLPD------DDDFLYRKDSARNINSTQTPNYVGGLSSATDSTAPDFVYKTAKAMNRSS--N 281

  Fly   458 ATVAINVVVTPKFSVPPVGPIETSEQGTVVMHCQAIGDPKPTIQWDKDLKYLSENNTDRERFRFL 522
            ..|.:.:.||..|.|      :::.:..:.:|...|            |..||.:::|   |...
plant   282 EQVGMLMNVTWSFKV------KSNHRHFIRIHFSDI------------LSNLSNSDSD---FYLF 325

  Fly   523 ENG--TLEIRN--------------VQVED-EGSYGCTIG-----NSAG-LKREDVQLVVKTTGD 564
            .||  .::::.              |.|.| .|....:||     ..|| |...::..|:..:|.
plant   326 VNGYWRVDVKPSEQPRLASPFFKDVVNVSDGSGLLNISIGTKEANKDAGFLNGLEMMEVLSKSGS 390

  Fly   565 GFAPEESGGDGFLVTRAVLITMTVALAYIVLVVGLMLWCRYRRQARKARLNDLSTKEAGGDQPDV 629
            .::...|.....:...||......||.:.:|   .|::.: ||:::|.:             |:|
plant   391 DYSNRSSSRVHIITGCAVAAAAASALVFSLL---FMVFLK-RRRSKKTK-------------PEV 438

  Fly   630 AGNGKGSEQEPCLSKQHNGHSKSRSKSSGDAQKSDDTACSQQSRASKKSAHI-----YEQLALPR 689
                :|:...|.  ..|.|.|            ||:...||...:..::.|:     :..:....
plant   439 ----EGTVWSPL--PLHRGGS------------SDNRPISQYHNSPLRNLHLGLTIPFTDILSAT 485

  Fly   690 SGLSELIQIGRGEFGDVFVGKLKATLVTSPSDKDADTEKQHSNSENGSGGSGSGSTTLSTLNEKR 754
            :...|.:.||:|.||.|:    ||.|   |....|..::       |..|||.|
plant   486 NNFDEQLLIGKGGFGYVY----KAIL---PDGTKAAIKR-------GKTGSGQG----------- 525

  Fly   755 RSKTSMDDIEEIKEEEQDQHNQSGLEQLVLVKALNKVKDEQACQEFRRQLDLLRAISHKGVVRLF 819
                                        :|              ||:.::.:|..|.|:.:|.|.
plant   526 ----------------------------IL--------------EFQTEIQVLSRIRHRHLVSLT 548

  Fly   820 GLCREKDPHYMVLEYTDWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIY 884
            |.|.|.....:|.|:.:.|.||:.|.            .|:.|.||..|.|.:....|||:|.::
plant   549 GYCEENSEMILVYEFMEKGTLKEHLY------------GSNLPSLTWKQRLEICIGAARGLDYLH 601

  Fly   885 ----RARFTHRDLATRNCVISSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQEDEY 945
                .....|||:.:.|.::....|.||:...|.|.....|.:...|......:|.||.:|..:.
plant   602 SSGSEGAIIHRDVKSTNILLDEHNIAKVADFGLSKIHNQDESNISINIKGTFGYLDPEYLQTHKL 666

  Fly   946 TTKSDIFAYGVVVWE-LFNQAT---KLPHEEL-------------TNEQVVQRSQAGSLEWSVAE 993
            |.|||::|:|||:.| ||.:..   .|||||:             |.::::..|..|.:|
plant   667 TEKSDVYAFGVVLLEVLFARPAIDPYLPHEEVNLSEWVMFCKSKGTIDEILDPSLIGQIE----- 726

  Fly   994 ATPDSLR---EILLSCWVSNPKERPS 1016
              .:||:   ||...|......||||
plant   727 --TNSLKKFMEIAEKCLKEYGDERPS 750

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otk	NP_523705.2	I-set	26..115	CDD:254352
		Ig	31..115	CDD:299845
		IGc2	133..195	CDD:197706
		Ig	268..373	CDD:299845	3/9 (33%)
		Ig	395..460	CDD:143165	18/90 (20%)
		I-set	468..559	CDD:254352	20/113 (18%)
		IGc2	484..549	CDD:197706	15/86 (17%)
		PTK_CCK4	686..1026	CDD:133178	88/355 (25%)
		STYKc	692..1020	CDD:214568	88/349 (25%)
AT2G23200	NP_179901.1	Malectin_like	41..383	CDD:289580	51/251 (20%)
		STKc_IRAK	494..759	CDD:270968	87/343 (25%)
		TyrKc	494..758	CDD:197581	87/343 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I2197
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050