Protein Alignment otk and Cntn6

DIOPT Version :10

• Sequence 1: NP_523705.2
• Gene: otk / 36283
• FlyBaseID: FBgn0004839
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: NP_059079.2
• Gene: Cntn6 / 53870
• MGIID: 1858223
• Length: 1028
• Species: Mus musculus
• Alignment Length: 599
• Identity: 142/599 - (23%)
• Similarity: 210/599 - (35%)
• Gaps: 157/599 - (26%)

  Fly    11 LVMALMMASVLASSSRFQR---VPQSQSVV-----ENESVKFECESTDSYSELHYDWLHNGHRIA 67
            ||:.|.:.:..|...||.|   :.:.|.|:     ....:...| :.:.|...||.|..||..|.
Mouse     7 LVILLPLINSCAGEGRFSRPIFIQEPQDVIFPLDLSRSEIILTC-TANGYPSPHYRWKQNGTDID 70

  Fly    68 YDKRVHQ--IGSNLHIEAVRRTEDVGNYVCIATNLASGAREASPPAKLSVIYLESASVQLLGS-- 128
            :....|.  .|.:|.|.:.|..:|:|.|.|:|||.....  .|..|||...|:|....:...:
Mouse    71 FGMTYHYRLDGGSLAISSPRTDQDIGIYQCLATNPVGTI--LSRKAKLQFAYIEDFETKTRSTVS 133

  Fly   129 --NRNELLLKCHVEGASGDLEPLEIEWYRNSEKLSTWKNVQLDQHRLIIRQPGS--------EDD 183
              ....::|.|   |.......|...|..|...|    .||.|:.|.:.:..|:        .|.
Mouse   134 VREGQGVVLLC---GPPPHFGELSYAWTFNDSPL----YVQEDKRRFVSQDTGNLYFAKVEPSDV 191

  Fly   184 GLYRCTASNAAGR----------VMSKQGYVYQSSVKCLPRLPRRKNEKMMESWDKQTFLCRGKR 238
            |.|.|..:|....          |:...|.:.:...|...|.|
Mouse   192 GNYTCFVTNKEAHRSVQGPPTPLVLRTDGVMGEYEPKIEVRFP---------------------- 234

  Fly   239 GGAAGLEALPAAPEDLRIVQGPIGQSIIKEGEPTALTCLYELPDELKNQRIQLRWRKDGKLLRQV 303
                  |.:.||.:           |.||      |.|.     .|.|....:.|::
Mouse   235 ------ETIQAAKD-----------SSIK------LECF-----ALGNPVPDISWKR-------- 263

  Fly   304 ELGGSAPIPGHSFDSGKDALLREDARLVLHKQNGTLSFASIIASDAGQYQC-----------QLQ 357
             |.|| |:||               ::...|....|........|.|.|:|           :.|
Mouse   264 -LDGS-PMPG---------------KIKYSKSQAILEIPKFQQEDEGFYECIAGNLRGRNLAKGQ 311

  Fly   358 LEAHAPINSSPGI----LEVIEQLKFVPQPTSKNLELDAVVAKVHCKAQGTPTPQVQWVRDGENT 418
            |..:||......|    |.:.:.|.:                  .|||.|.|.|...|:::|:..
Mouse   312 LIFYAPPEWEQKIQNTYLSIYDSLFW------------------ECKASGNPNPSYTWLKNGQRL 358

  Fly   419 TLPDHVEVDANGTLIFRNVNSEHRGNYTCLATNSQGQINATVAINVVVT-PKFSVPPVGPIETSE 482
            ...:.:::: |||||...:|....|.|.|.|.|....|.|...:.|:.: |.||..|:..|...:
Mouse   359 NTEERIQIE-NGTLIITMLNISDSGIYQCAAENKYQTIYANAELRVLASAPDFSKNPIKKISVVQ 422

  Fly   483 -QGTVVMHCQAIGDPKPTIQWDKDLKYLSENNTDRERFRFLENGTLEIRNVQVEDEGSYGCTIGN 546
             .|.:.:.|:....||.:|.|.:.    :||....:|..|||:|:|:|.||...|.|||.|...|
Mouse   423 VGGDISIECKPNAFPKASISWKRG----TENLKQSKRVLFLEDGSLKICNVTRADAGSYTCVATN 483

  Fly   547 SAGLKREDVQLVVK 560
            ..|..:....||||
Mouse   484 QFGNGKSSGGLVVK 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
otk	NP_523705.2	Ig_3	31..99	CDD:464046	20/74 (27%)
		Ig strand B	133..137	CDD:409353	1/3 (33%)
		Ig	<135..197	CDD:472250	17/79 (22%)
		Ig strand C	150..154	CDD:409353	0/3 (0%)
		Ig strand E	171..175	CDD:409353	1/3 (33%)
		Ig strand F	185..190	CDD:409353	2/4 (50%)
		Ig	265..360	CDD:472250	21/105 (20%)
		Ig strand B	272..276	CDD:409571	1/3 (33%)
		Ig strand C	290..294	CDD:409571	0/3 (0%)
		Ig strand E	337..341	CDD:409571	1/3 (33%)
		Ig strand F	351..356	CDD:409571	2/15 (13%)
		Ig	395..460	CDD:409353	21/64 (33%)
		Ig strand B	395..399	CDD:409353	0/3 (0%)
		Ig strand C	408..412	CDD:409353	0/3 (0%)
		Ig strand E	430..434	CDD:409353	3/3 (100%)
		Ig strand F	444..449	CDD:409353	2/4 (50%)
		Ig strand G	457..460	CDD:409353	1/2 (50%)
		I-set	468..559	CDD:400151	30/91 (33%)
		Ig strand B	486..490	CDD:409570	0/3 (0%)
		Ig strand C	499..503	CDD:409570	1/3 (33%)
		Ig strand E	525..529	CDD:409570	2/3 (67%)
		Ig strand F	539..544	CDD:409570	3/4 (75%)
		Ig strand G	552..555	CDD:409570	0/2 (0%)
		PTK_CCK4	686..1026	CDD:133178
Cntn6	NP_059079.2	Ig	26..120	CDD:472250	26/96 (27%)
		Ig strand B	46..50	CDD:409353	0/3 (0%)
		Ig strand C	59..63	CDD:409353	2/3 (67%)
		Ig strand E	82..86	CDD:409353	1/3 (33%)
		Ig strand F	97..102	CDD:409353	2/4 (50%)
		Ig strand G	111..114	CDD:409353	1/2 (50%)
		Ig	129..214	CDD:472250	17/91 (19%)
		Ig strand B	140..144	CDD:409353	1/3 (33%)
		Ig strand C	154..158	CDD:409353	0/3 (0%)
		Ig strand E	179..183	CDD:409353	1/3 (33%)
		Ig strand F	193..198	CDD:409353	2/4 (50%)
		Ig strand G	209..212	CDD:409353	0/2 (0%)
		Ig	227..315	CDD:472250	28/162 (17%)
		Ig strand B	245..249	CDD:409353	3/9 (33%)
		Ig strand C	258..262	CDD:409353	0/3 (0%)
		Ig strand E	280..284	CDD:409353	1/3 (33%)
		Ig strand F	294..299	CDD:409353	2/4 (50%)
		Ig strand G	307..310	CDD:409353	0/2 (0%)
		Ig	319..403	CDD:472250	24/102 (24%)
		Ig strand B	335..339	CDD:143205	1/21 (5%)
		Ig strand C	348..352	CDD:143205	0/3 (0%)
		Ig strand E	369..373	CDD:143205	3/3 (100%)
		Ig strand F	383..388	CDD:143205	2/4 (50%)
		Ig strand G	396..399	CDD:143205	1/2 (50%)
		Ig5_Contactin	408..496	CDD:409358	30/91 (33%)
		Ig strand A	408..413	CDD:409358	3/4 (75%)
		Ig strand A'	416..421	CDD:409358	1/4 (25%)
		Ig strand B	425..432	CDD:409358	1/6 (17%)
		Ig strand C	440..444	CDD:409358	1/3 (33%)
		Ig strand D	458..461	CDD:409358	2/2 (100%)
		Ig strand E	462..467	CDD:409358	2/4 (50%)
		Ig strand F	475..483	CDD:409358	4/7 (57%)
		Ig strand G	489..496	CDD:409358	1/6 (17%)
		Ig	500..598	CDD:472250
		Ig strand B	517..521	CDD:409353
		Ig strand C	532..536	CDD:409353
		Ig strand E	560..564	CDD:409353
		Ig strand F	574..579	CDD:409353
		Ig strand G	587..590	CDD:409353
		FN3	598..691	CDD:238020
		FN3	<620..>912	CDD:442628
		FN3	903..983	CDD:214495