Protein Alignment otk and btl

DIOPT Version :9

• Sequence 1: NP_523705.2
• Gene: otk / 36283
• FlyBaseID: FBgn0004839
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: NP_001014583.1
• Gene: btl / 39564
• FlyBaseID: FBgn0285896
• Length: 1052
• Species: Drosophila melanogaster
• Alignment Length: 1103
• Identity: 241/1103 - (21%)
• Similarity: 403/1103 - (36%)
• Gaps: 344/1103 - (31%)

  Fly    28 QRVPQSQSVVENESVKFECESTDSYSE-LHYDWLHNGHRIAYDKRVHQIGSNLHIEAVR------ 85
            |.:|::.........:..|...|..:: ::..||||..:|        :|....|:..|
  Fly   146 QPLPKTVQRTAGGLFQLNCSPMDPDAKGVNISWLHNDTQI--------LGGRGRIKLKRWSLTVG 202

  Fly    86 --RTEDVGNY---VCIATNLASGAREASPPAKLSVI------------YLESASVQLLGSNRNEL 133
              :.||.|:|   :|:..:.     :.|.|.:|.||            |..:.|: .||.|   :
  Fly   203 QLQPEDAGSYHCELCVEQDC-----QRSNPTQLEVISRKHTVPMLKPGYPRNTSI-ALGDN---V 258

  Fly   134 LLKCHVEGASGDLEPLEIEWYRNS---------EKLSTWKNVQLDQHRLIIR--QP-----GS-- 180
            .::|.:|.::  ||| :|.|....         ::|.....:.:|..|||.|  :|     |:
  Fly   259 SIECLLEDSA--LEP-KITWLHKGNADNIDDLLQRLREQSQLPVDVTRLITRMDEPQVLRLGNVL 320

  Fly   181 -EDDGLYRCTASNAAGRVMSKQGYV--YQSSVKCLPRLPRRKNEKMMESWDKQTFLCRGKRGGAA 242
             ||.|.|.|.|.|..||.:: ..||  |..|
  Fly   321 MEDGGWYICIAENQVGRTVA-ASYVDLYSPS---------------------------------- 350

  Fly   243 GLEALPAAPEDLRIVQGPIGQSIIKEGEPTALTCLYELPDELKNQRIQLRWRKDGKLLRQVELGG 307
              :...........|..||         |||.|. .:..|:::|...:..             ||
  Fly   351 --DTTTVRTTTTTTVASPI---------PTASTG-EDNDDDVENPAAEAS-------------GG 390

  Fly   308 SAPIPGHSFDSGKDALLREDARLVLHKQNG-TLSFASIIASDAGQYQCQLQLEAHAPINSSPGIL 371
            ..|           .:.|::.:.:.|..:| |::.|
  Fly   391 VGP-----------PVFRKELKRLQHSLSGNTVNLA----------------------------- 415

  Fly   372 EVIEQLKFVPQPTSKNLELDAVVAKVHCKAQGTPTPQVQWVRDGENTTLPDHVEVDANGTLIFRN 436
                                       |...|  ...:.|.:|.:.......|.|..|.||.|..
  Fly   416 ---------------------------CPVYG--KANITWTKDKKPLNRELGVYVQKNWTLRFVE 451

  Fly   437 VNSEHRGNYTCLATNSQG--QINATVAIN-------VVVTPKFSVPPVGPIETSEQGTVVMHCQA 492
            ..||..|.|.|...|:.|  |.:.:|.||       ::|.|:.....|       .|::||.|..
  Fly   452 ATSEDSGLYNCKVCNAWGCIQFDFSVQINDRTRSAPIIVVPQNQTVKV-------NGSLVMKCTV 509

  Fly   493 IGDPKPTIQWDK-DLKYLSEN---NTDRERFRFL---ENGTLEIRNVQVEDEGSYGCTIGNSAGL 550
            ..|..||:.|.: .||..|.:   :.:.:...|.   ::..|.:|||..:.||.|.|...:..|.
  Fly   510 YSDLHPTVSWKRVVLKNASLDGLKSVEIQNLNFTVTNDSVVLTLRNVTFDQEGWYTCLASSGLGR 574

  Fly   551 KREDVQLVVKTTGDGFAPEESGGDGFLVTRAVLITMTVALAYIVLV-------VGLMLWCRYRRQ 608
            ....|.|.|.:.   ..|.|.    :.:..|..:..|:|...||.:       :..||....|.:
  Fly   575 SNSSVYLRVVSP---LPPLEI----YALLHAHPLGFTLAAITIVALFLLGSAFITFMLRRLRREK 632

  Fly   609 ARKARLNDLS--TKEA-----GGDQPDVAGNGKGSEQEPC--LSKQHNGHSKSRSKSSGDAQKSD 664
            ..|.|:..:.  ||:.     ||::.  :|...|..|.|.  :.||....|.:.:..:..||..:
  Fly   633 LLKLRIETVHQWTKKVIIYRPGGEEG--SGCSSGDLQMPVIRIEKQRTTVSTTGTGGTDPAQGFN 695

  Fly   665 DTACSQQSRASKKSAHIYE-----QLALPRSGLSELIQIGRGEFGDVFVGKLKATLVTSPSDKDA 724
            :                ||     ...:||..||....:|.|.||.|.:.:.:. |..||.
  Fly   696 E----------------YEFPLDSNWEIPRQQLSLGSILGEGAFGRVVMAEAEG-LPRSPQ---- 739

  Fly   725 DTEKQHSNSENGSGGSGSGSTTLSTLNEKRRSKTSMDDIEEIKEEEQDQHNQSGLEQLVLVKALN 789
                                     |.|      ::..::.:|||    |..:.:..||
  Fly   740 -------------------------LAE------TIVAVKMVKEE----HTDTDMASLV------ 763

  Fly   790 KVKDEQACQEFRRQLDLLRAI-SHKGVVRLFGLCREKDPHYMVLEYTDWGDLKQFLLAT---AGK 850
                        |::::::.| .|..::.|.|.|.:..|.::::||...|:||.||...   |.:
  Fly   764 ------------REMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQ 816

  Fly   851 VNTATAGSSSPPPLTTSQVLA------VAYQIARGMDAIYRARFTHRDLATRNCVISSEFIVKVS 909
            ..:.:.|.....||.::|.|.      .|:||||||:.:...|..|||||.||.::|..:::|::
  Fly   817 RRSDSDGYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIA 881

  Fly   910 YPALCKDKYSREYH-KHRNTLLPIRWLAPECIQEDEYTTKSDIFAYGVVVWELFNQATK-LPH-- 970
            ...|.:|....||: |:.|..|||:|:|||.:||.:|.::||:::|||::||:.....: .||
  Fly   882 DFGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHIL 946

  Fly   971 --EELTNEQVVQRSQAGSLEWSVAEATPDSLREILLSCWVSNPKERPSFSQLGAALSKAMQSA 1031
              |||.:..:..:......:.|:      ::..::..||......||:|::|..:....:|.|
  Fly   947 SAEELYSYLITGQRMEKPAKCSL------NIYVVMRQCWHFESCARPTFAELVESFDGILQQA 1003

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
otk	NP_523705.2	I-set	26..115	CDD:254352	20/98 (20%)
		Ig	31..115	CDD:299845	19/95 (20%)
		IGc2	133..195	CDD:197706	22/80 (28%)
		Ig	268..373	CDD:299845	14/105 (13%)
		Ig	395..460	CDD:143165	18/66 (27%)
		I-set	468..559	CDD:254352	25/97 (26%)
		IGc2	484..549	CDD:197706	20/71 (28%)
		PTK_CCK4	686..1026	CDD:133178	92/355 (26%)
		STYKc	692..1020	CDD:214568	89/343 (26%)
btl	NP_001014583.1	IG_like	149..232	CDD:214653	19/95 (20%)
		IGc2	157..215	CDD:197706	14/65 (22%)
		IG	247..336	CDD:214652	26/95 (27%)
		Ig	258..340	CDD:143165	24/84 (29%)
		I-set	394..479	CDD:254352	24/142 (17%)
		IGc2	408..469	CDD:197706	19/118 (16%)
		IG_like	492..583	CDD:214653	25/97 (26%)
		Ig	507..583	CDD:299845	20/75 (27%)
		PKc_like	700..1000	CDD:304357	92/363 (25%)
		TyrKc	712..996	CDD:197581	90/347 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I2197
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960