DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otk and Cfp

DIOPT Version :9

Sequence 1:	NP_523705.2	Gene:	otk / 36283	FlyBaseID:	FBgn0004839	Length:	1033	Species:	Drosophila melanogaster
Sequence 2:	NP_001100227.1	Gene:	Cfp / 299314	RGDID:	1594557	Length:	465	Species:	Rattus norvegicus

Alignment Length:	178	Identity:	31/178 - (17%)
Similarity:	57/178 - (32%)	Gaps:	65/178 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   832 LEYTDWGDLKQFLLATAGKVNTATAGSSSPPPLTTSQVLAVAYQIARGMDAIYRAR-FTHRDLAT 895
            ::...|..|...:|.|.|          |.|.|..:|     |:...|     |.: ...||:..
  Rat     5 MQAPQWLLLLLLILPTTG----------SDPVLCFTQ-----YEEPSG-----RCKGLLGRDIRV 49

  Fly   896 RNCVISSEFIVKVSYPALCKDKYSREYHKHRNTLLPIRWLAPECIQEDEYTTKSDIFAYGVVVWE 960
            .:|.:::.:..:.....||:...|.:            |.|                      |.
  Rat    50 EDCCLNTAYAFQEHDGGLCQSCRSPQ------------WSA----------------------WS 80

  Fly   961 LF-------NQATKLPHEELTNE--QVVQRSQAGSLEWSVAEATPDSL 999
            .:       ::.::|.|......  |..:::..|:|||.: :|..|.|
  Rat    81 SWGPCSVTCSEGSQLRHRRCVGRGGQCSEKAAPGTLEWQL-QACEDQL 127

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otk	NP_523705.2	I-set	26..115	CDD:254352
		Ig	31..115	CDD:299845
		IGc2	133..195	CDD:197706
		Ig	268..373	CDD:299845
		Ig	395..460	CDD:143165
		I-set	468..559	CDD:254352
		IGc2	484..549	CDD:197706
		PTK_CCK4	686..1026	CDD:133178	31/178 (17%)
		STYKc	692..1020	CDD:214568	31/178 (17%)
Cfp	NP_001100227.1	TSP_1	77..128	CDD:278517	12/74 (16%)
		TSP_1	136..184	CDD:278517
		TSP1	192..251	CDD:214559
		TSP_1	257..303	CDD:278517
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4475
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900