Protein Alignment otk and Cntn6

DIOPT Version :10

• Sequence 1: NP_523705.2
• Gene: otk / 36283
• FlyBaseID: FBgn0004839
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: NP_037357.1
• Gene: Cntn6 / 27256
• RGDID: 62008
• Length: 1028
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 147/591 - (24%)
• Similarity: 219/591 - (37%)
• Gaps: 141/591 - (23%)

  Fly    11 LVMALMMASVLASSSRFQR---VPQSQSVV-----ENESVKFECESTDSYSELHYDWLHNGHRIA 67
            ||:.|.:.:..|..|||.|   :.:.|.|:     ....:...| :...|...||.|..||..|.
  Rat     7 LVILLPLINSCAGESRFTRPIFIQEPQDVIFPLDLSRSEIILSC-TASGYPSPHYRWKQNGTDID 70

  Fly    68 YDKRVHQ--IGSNLHIEAVRRTEDVGNYVCIATNLASGAREASPPAKLSVIYLE-----SASVQL 125
            :....|.  .|.:|.|.:.|..:|:|.|.|:|||.....  .|..|||...|:|     |.|...
  Rat    71 FSMTYHYRLDGGSLAISSPRTDQDIGIYQCLATNPVGTI--LSRKAKLQFAYIEDFETKSRSTVS 133

  Fly   126 LGSNRNELLLKCHVEGASGDLEPLEIEWYRNSEKLSTWKNVQLDQHRLIIRQPGS--------ED 182
            :...:..:|| |   |.......|..:|..|...|    .||.|:.|.:.:..|:        .|
  Rat   134 VREGQGVVLL-C---GPPPHFGELSYDWTFNDNPL----YVQEDKRRFVSQNTGNLYIAKVEPSD 190

  Fly   183 DGLYRCTASNAAGRVMSKQGYVYQSSVKCLPRLPR-RKNEKMMESWDKQTFLCRGKRGGAAGLEA 246
            .|.|.|..:|.... .|.||          |..|. ::.:.:|..::.:             :|.
  Rat   191 VGNYTCFVTNKEAH-RSVQG----------PPTPLVQRTDGVMGEYEPK-------------IEV 231

  Fly   247 LPAAPEDLRIVQGPIGQSIIKEGEPTALTCLYELPDELKNQRIQLRWRKDGKLLRQVELGGSAPI 311
              ..||.::..:    .|.:|      |.|.     .|.|....:.||:         |.|| |:
  Rat   232 --RFPETIQAAK----DSSVK------LECF-----ALGNPVPDISWRR---------LDGS-PM 269

  Fly   312 PGHSFDSGKDALLREDARLVLHKQNGTLSFASIIASDAGQYQC-----------QLQLEAHAPIN 365
            ||               ::.......||........|.|.|:|           :.||..:||..
  Rat   270 PG---------------KVKYSNSQATLEIPKFQQEDEGFYECVAGNLRGRNLAKGQLIFYAPPE 319

  Fly   366 SSPGI----LEVIEQLKFVPQPTSKNLELDAVVAKVHCKAQGTPTPQVQWVRDGENTTLPDHVEV 426
            ....|    |.:.:.|.:                  .|||.|.|.|...|:::||.....:.::.
  Rat   320 WEQKIQNTYLSIYDSLFW------------------ECKASGNPNPSYTWLKNGERLNTEERIQT 366

  Fly   427 DANGTLIFRNVNSEHRGNYTCLATNSQGQINATVAINVVVT-PKFSVPPVGPIETSE-QGTVVMH 489
            : |||||...:|....|.|.|.|.|....|.|...:.|:.: |.||..|:..|...: .|.:.:.
  Rat   367 E-NGTLIITMLNVSDSGIYQCAAENKYQTIYANAELRVLASAPDFSKNPIKKISVVQVGGDISIE 430

  Fly   490 CQAIGDPKPTIQWDKDLKYLSENNTDRERFRFLENGTLEIRNVQVEDEGSYGCTIGNSAGLKRED 554
            |:....||.:|.|.:.    :||....:|..|||:|:|:|.||...|.|||.|...|..|..:..
  Rat   431 CKPNAFPKASISWKRG----TENLKQSKRVFFLEDGSLKICNVTRSDAGSYTCVATNQFGNGKSS 491

  Fly   555 VQLVVK 560
            ..|:||
  Rat   492 GSLIVK 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
otk	NP_523705.2	Ig_3	31..99	CDD:464046	20/74 (27%)
		Ig strand B	133..137	CDD:409353	2/3 (67%)
		Ig	<135..197	CDD:472250	17/69 (25%)
		Ig strand C	150..154	CDD:409353	0/3 (0%)
		Ig strand E	171..175	CDD:409353	1/3 (33%)
		Ig strand F	185..190	CDD:409353	2/4 (50%)
		Ig	265..360	CDD:472250	21/105 (20%)
		Ig strand B	272..276	CDD:409571	1/3 (33%)
		Ig strand C	290..294	CDD:409571	0/3 (0%)
		Ig strand E	337..341	CDD:409571	2/3 (67%)
		Ig strand F	351..356	CDD:409571	2/15 (13%)
		Ig	395..460	CDD:409353	22/64 (34%)
		Ig strand B	395..399	CDD:409353	0/3 (0%)
		Ig strand C	408..412	CDD:409353	0/3 (0%)
		Ig strand E	430..434	CDD:409353	3/3 (100%)
		Ig strand F	444..449	CDD:409353	2/4 (50%)
		Ig strand G	457..460	CDD:409353	1/2 (50%)
		I-set	468..559	CDD:400151	30/91 (33%)
		Ig strand B	486..490	CDD:409570	0/3 (0%)
		Ig strand C	499..503	CDD:409570	1/3 (33%)
		Ig strand E	525..529	CDD:409570	2/3 (67%)
		Ig strand F	539..544	CDD:409570	3/4 (75%)
		Ig strand G	552..555	CDD:409570	0/2 (0%)
		PTK_CCK4	686..1026	CDD:133178
Cntn6	NP_037357.1	Ig	26..120	CDD:472250	26/96 (27%)
		Ig strand B	46..50	CDD:409353	0/3 (0%)
		Ig strand C	59..63	CDD:409353	2/3 (67%)
		Ig strand E	82..86	CDD:409353	1/3 (33%)
		Ig strand F	97..102	CDD:409353	2/4 (50%)
		Ig strand G	111..114	CDD:409353	1/2 (50%)
		Ig	129..214	CDD:472250	23/103 (22%)
		Ig strand B	140..144	CDD:409353	2/4 (50%)
		Ig strand C	154..158	CDD:409353	0/3 (0%)
		Ig strand E	179..183	CDD:409353	1/3 (33%)
		Ig strand F	193..198	CDD:409353	2/4 (50%)
		Ig strand G	209..212	CDD:409353	2/12 (17%)
		Ig	227..315	CDD:472250	25/142 (18%)
		Ig strand B	245..249	CDD:409353	2/9 (22%)
		Ig strand C	258..262	CDD:409353	0/3 (0%)
		Ig strand E	280..284	CDD:409353	2/3 (67%)
		Ig strand F	294..299	CDD:409353	2/4 (50%)
		Ig strand G	307..310	CDD:409353	0/2 (0%)
		Ig	319..403	CDD:472250	25/102 (25%)
		Ig strand B	335..339	CDD:143205	1/21 (5%)
		Ig strand C	348..352	CDD:143205	0/3 (0%)
		Ig strand E	369..373	CDD:143205	3/3 (100%)
		Ig strand F	383..388	CDD:143205	2/4 (50%)
		Ig strand G	396..399	CDD:143205	1/2 (50%)
		Ig5_Contactin	408..496	CDD:409358	30/91 (33%)
		Ig strand A	408..413	CDD:409358	3/4 (75%)
		Ig strand A'	416..421	CDD:409358	1/4 (25%)
		Ig strand B	425..432	CDD:409358	1/6 (17%)
		Ig strand C	440..444	CDD:409358	1/3 (33%)
		Ig strand D	458..461	CDD:409358	2/2 (100%)
		Ig strand E	462..467	CDD:409358	2/4 (50%)
		Ig strand F	475..483	CDD:409358	4/7 (57%)
		Ig strand G	489..496	CDD:409358	1/6 (17%)
		Ig	500..598	CDD:472250
		Ig strand B	517..521	CDD:409353
		Ig strand C	532..536	CDD:409353
		Ig strand E	560..564	CDD:409353
		Ig strand F	574..579	CDD:409353
		Ig strand G	587..590	CDD:409353
		FN3	598..691	CDD:238020
		FN3	<620..>912	CDD:442628
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	887..908
		FN3	903..983	CDD:214495