DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment otk and Il1rl1

DIOPT Version :9

Sequence 1:	NP_523705.2	Gene:	otk / 36283	FlyBaseID:	FBgn0004839	Length:	1033	Species:	Drosophila melanogaster
Sequence 2:	NP_001121161.1	Gene:	Il1rl1 / 25556	RGDID:	2894	Length:	566	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	74/312 - (23%)
Similarity:	102/312 - (32%)	Gaps:	100/312 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 TSKNLELDAVVAKVHCKAQGTPTPQVQWVRDGENTTLP----DHVEVDANGTLIFRNVNSEHRGN 444
            ||..||.:|::  |.|..:|.....|:|.....|..:|    :.:.| :...|.|.....|..|.
  Rat    29 TSWGLENEALI--VRCPQRGGAINPVEWYYSNTNERIPTQKRNRIFV-SRDRLKFLPAKVEDSGI 90

  Fly   445 YTCLATNSQ----GQINATVAINVVVTPKFSVPPVGPIETSEQGTVVMHCQAIGDPK------PT 499
            |||:..:.:    |.:|.|:         :..||...|.     ..:|:....|..|      ||
  Rat    91 YTCVIRSPESIKTGSLNVTI---------YKRPPNCKIP-----DYMMYSTVDGSDKNSKITCPT 141

  Fly   500 I---------QWDKDLKYLSENNTDRERFRFLENGTLEIRNVQVEDEGSYGCTIGNSAGLKREDV 555
            |         ||.|:.|.|     ...||| .....|.|..|...|||.|.|...::     |:.
  Rat   142 IALYNWTAPVQWFKNCKAL-----QGPRFR-AHMSYLFIDKVSHVDEGDYTCRFTHT-----ENG 195

  Fly   556 QLVVKTTGDGFAPEESGGDGFLV--------TRAVLITMTVALA----------YIVLVVGLMLW 602
            ...:.|....|..||.|...|.|        |..|.|..|..:|          ::.     :||
  Rat   196 TNYIVTATRSFTVEEKGFSTFPVITNPPHNYTVEVEIGKTANIACSACFGTASQFVA-----VLW 255

  Fly   603 CRYRRQARKARLNDLSTKEAGGDQPDVAGNGKGSEQEPCLSKQHNGHSKSRS 654
                 |..|.|:...               ||...||      ..|.:||.|
  Rat   256 -----QINKTRIGSF---------------GKARIQE------EKGPNKSSS 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
otk	NP_523705.2	I-set	26..115	CDD:254352
		Ig	31..115	CDD:299845
		IGc2	133..195	CDD:197706
		Ig	268..373	CDD:299845
		Ig	395..460	CDD:143165	17/72 (24%)
		I-set	468..559	CDD:254352	26/105 (25%)
		IGc2	484..549	CDD:197706	22/79 (28%)
		PTK_CCK4	686..1026	CDD:133178
		STYKc	692..1020	CDD:214568
Il1rl1	NP_001121161.1	Ig	28..110	CDD:299845	22/83 (27%)
		IG_like	31..110	CDD:214653	20/81 (25%)
		Ig2_IL1R_like	123..210	CDD:143234	25/97 (26%)
		IG_like	136..209	CDD:214653	22/83 (27%)
		Flexible linker. /evidence=ECO:0000250	204..216		4/11 (36%)
		Ig	217..314	CDD:299845	19/96 (20%)
		TIR	384..539	CDD:279864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910