| Sequence 1: | NP_523705.2 | Gene: | otk / 36283 | FlyBaseID: | FBgn0004839 | Length: | 1033 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001392991.1 | Gene: | Nptn / 20320 | MGIID: | 108077 | Length: | 397 | Species: | Mus musculus |
| Alignment Length: | 467 | Identity: | 103/467 - (22%) |
|---|---|---|---|
| Similarity: | 172/467 - (36%) | Gaps: | 145/467 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 240 GAAGLEAL---------PAAPEDLRIVQGPIGQSIIKEGEPTALTCLYELPDELKNQRIQLRW-- 293
Fly 294 ---------RK--DGKLLRQVELGGSAPIPGHSFDSGKDALLREDARLVLHKQNGTLSFASIIAS 347
Fly 348 DAGQYQCQLQLE-AHAPINSSPGI--------LEVIEQLKFVPQPTSKNLELDAVVAKVHCKAQG 403
Fly 404 TPTPQV----QWVRDGENTTLPDHVEVDA---NGTLIFRNVN---SEHRGNYTCL-ATNSQGQIN 457
Fly 458 ATVAINVVVTPKFSVPPVGPIETSEQGT----VVMHCQAIGDPKPTIQWDKDLKYLSENNTDRE- 517
Fly 518 -----RFRFL---ENGT-LEIRNVQV-EDEGSYGCTIGNSAGLKREDVQLVVKTTGDGFAPEESG 572
Fly 573 GDGFLVTRAVLITMTVALAYIVLVVGLMLWCRYRRQARKARLNDLSTKEAGGDQPDVAGNGKGSE 637
Fly 638 QEPCLSKQHNGH 649 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| otk | NP_523705.2 | Ig_3 | 31..99 | CDD:464046 | |
| Ig strand B | 133..137 | CDD:409353 | |||
| Ig | <135..197 | CDD:472250 | |||
| Ig strand C | 150..154 | CDD:409353 | |||
| Ig strand E | 171..175 | CDD:409353 | |||
| Ig strand F | 185..190 | CDD:409353 | |||
| Ig | 265..360 | CDD:472250 | 20/108 (19%) | ||
| Ig strand B | 272..276 | CDD:409571 | 1/3 (33%) | ||
| Ig strand C | 290..294 | CDD:409571 | 1/14 (7%) | ||
| Ig strand E | 337..341 | CDD:409571 | 0/3 (0%) | ||
| Ig strand F | 351..356 | CDD:409571 | 2/4 (50%) | ||
| Ig | 395..460 | CDD:409353 | 17/75 (23%) | ||
| Ig strand B | 395..399 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 408..412 | CDD:409353 | 0/7 (0%) | ||
| Ig strand E | 430..434 | CDD:409353 | 0/3 (0%) | ||
| Ig strand F | 444..449 | CDD:409353 | 2/5 (40%) | ||
| Ig strand G | 457..460 | CDD:409353 | 2/2 (100%) | ||
| I-set | 468..559 | CDD:400151 | 32/105 (30%) | ||
| Ig strand B | 486..490 | CDD:409570 | 1/3 (33%) | ||
| Ig strand C | 499..503 | CDD:409570 | 0/3 (0%) | ||
| Ig strand E | 525..529 | CDD:409570 | 2/4 (50%) | ||
| Ig strand F | 539..544 | CDD:409570 | 2/4 (50%) | ||
| Ig strand G | 552..555 | CDD:409570 | 0/2 (0%) | ||
| PTK_CCK4 | 686..1026 | CDD:133178 | |||
| Nptn | NP_001392991.1 | Ig | 31..146 | CDD:472250 | 25/142 (18%) |
| Ig strand B | 48..52 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 61..65 | CDD:409353 | 0/3 (0%) | ||
| Ig strand E | 99..103 | CDD:409353 | 2/4 (50%) | ||
| Ig strand F | 113..118 | CDD:409353 | 2/4 (50%) | ||
| Ig strand G | 137..140 | CDD:409353 | 0/2 (0%) | ||
| Narpin, mediates binding with FGFR1 and has antidepressant-like activity. /evidence=ECO:0000250 | 149..161 | 3/14 (21%) | |||
| Ig | 167..218 | CDD:472250 | 12/58 (21%) | ||
| Ig strand C | 179..184 | CDD:409353 | 0/4 (0%) | ||
| Ig strand E | 200..204 | CDD:409353 | 0/3 (0%) | ||
| Ig strand F | 214..218 | CDD:409353 | 1/3 (33%) | ||
| Ig | 249..332 | CDD:472250 | 29/88 (33%) | ||
| Ig strand B | 254..258 | CDD:409353 | 1/3 (33%) | ||
| Ig strand C | 267..273 | CDD:409353 | 2/10 (20%) | ||
| Ig strand E | 297..301 | CDD:409353 | 2/3 (67%) | ||
| Ig strand F | 312..317 | CDD:409353 | 2/4 (50%) | ||
| Ig strand G | 325..328 | CDD:409353 | 0/2 (0%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 364..397 | 9/40 (23%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||