DRSC/TRiP Functional Genomics Resources

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Protein Alignment otk and Il1rl2

DIOPT Version :9

Sequence 1:NP_523705.2 Gene:otk / 36283 FlyBaseID:FBgn0004839 Length:1033 Species:Drosophila melanogaster
Sequence 2:NP_598259.2 Gene:Il1rl2 / 171106 RGDID:621782 Length:561 Species:Rattus norvegicus


Alignment Length:437 Identity:83/437 - (18%)
Similarity:148/437 - (33%) Gaps:145/437 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   265 IIKEGEPTALTCLYELPDELKNQRIQLRWRKDGKLLRQVELGGSAPIPGHSFDSGKDALLREDAR 329
            :|.||:|....|.|   ..:.|..:.|.|                    |...|.....:....|
  Rat    33 MISEGQPFPFNCTY---PPVTNGAVNLTW--------------------HRTPSKSPISINRHVR 74

  Fly   330 LVLHKQNGTLSFASIIASDAGQYQCQLQLEAHAPINSSPGILEVIEQLKFVPQPTSKNLELDAVV 394
              :|:....:.|..:...|:|.|||.:: :||                      :...:.::..|
  Rat    75 --IHQDQSWILFLPLALEDSGIYQCVIK-DAH----------------------SCYRIAINLTV 114

  Fly   395 AKVH-CKAQ------GTPTPQVQWVRDGENTTL------PDHVEVDA------------------ 428
            .:.| |.:.      .:.....||:..|::.:|      |:...:|:                  
  Rat   115 FRKHWCDSSNEESSINSSDEYQQWLPIGKSGSLTCHLYFPESCVLDSIKWYKGCEEIKVSKKFCP 179

  Fly   429 NGT-LIFRNVNSEHRGNYTCLATNSQ-GQINAT---VAINVVVT------PKFSVPPVGPIETSE 482
            .|| |:..|::.|..|:|.|.|..:. |:|...   :|:|....      |..:.|....||...
  Rat   180 TGTKLLVNNIDVEDSGSYACSARLTHLGRIFTVRNYIAVNTKEVGSGGRIPNITYPKNNSIEVQL 244

  Fly   483 QGTVVMHCQAIGDPKPTIQWDKDLKYLSENNT-------DRERFRFLENGTLEIRN--------- 531
            ..|:::.|. |.|.|.    :.:|:....|||       |.:|.:......|.:||         
  Rat   245 GSTLIVDCN-ITDTKE----NTNLRCWRVNNTLVDDYYNDSKRIQEGIETNLSLRNHILYTVNIT 304

  Fly   532 ---VQVEDEG-SYGCTIGNSAGLKREDVQLVVKTTGDGFAPEESGGDGFLVTRAVLITMTVALAY 592
               |::||.| .:.|..|.||      ..:::|.....|.....||    :...:|:.:::...|
  Rat   305 FLEVKMEDYGHPFTCHAGVSA------AYIILKRPAPDFRAYLIGG----LMAFLLLAVSILYIY 359

  Fly   593 IVLVVGLMLWCR--------------------YRRQARKARLNDLST 619
            ....|.::||.|                    |.:..|:::.:|:.|
  Rat   360 NTFKVDIVLWYRSTFHTAQAPDDEKLYDAYVLYPKYPRESQGHDVDT 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
otkNP_523705.2 I-set 26..115 CDD:254352
Ig 31..115 CDD:299845
IGc2 133..195 CDD:197706
Ig 268..373 CDD:299845 20/104 (19%)
Ig 395..460 CDD:143165 19/100 (19%)
I-set 468..559 CDD:254352 26/110 (24%)
IGc2 484..549 CDD:197706 21/84 (25%)
PTK_CCK4 686..1026 CDD:133178
STYKc 692..1020 CDD:214568
Il1rl2NP_598259.2 Ig 26..115 CDD:416386 21/129 (16%)
Ig strand A' 31..35 CDD:409353 0/1 (0%)
Ig strand B 39..44 CDD:409353 1/4 (25%)
Ig strand C 55..59 CDD:409353 2/23 (9%)
Ig strand C' 64..66 CDD:409353 0/1 (0%)
Ig strand D 74..78 CDD:409353 2/5 (40%)
Ig strand E 80..84 CDD:409353 0/3 (0%)
Ig strand F 93..101 CDD:409353 4/8 (50%)
Ig strand G 104..115 CDD:409353 0/10 (0%)
Ig 133..222 CDD:416386 19/88 (22%)
Ig strand A 135..140 CDD:409353 2/4 (50%)
Ig strand B 145..149 CDD:409353 1/3 (33%)
Ig strand C 161..166 CDD:409353 0/4 (0%)
Ig strand C' 169..171 CDD:409353 0/1 (0%)
Ig strand D 176..180 CDD:409353 0/3 (0%)
Ig strand E 182..187 CDD:409353 2/4 (50%)
Ig strand F 196..205 CDD:409353 3/8 (38%)
Ig strand G 208..221 CDD:409353 3/12 (25%)
Ig 230..330 CDD:416386 26/110 (24%)
Ig strand A 230..233 CDD:409353 1/2 (50%)
Ig strand A' 238..241 CDD:409353 0/2 (0%)
Ig strand B 246..255 CDD:409353 2/9 (22%)
Ig strand C 262..268 CDD:409353 1/5 (20%)
Ig strand C' 270..273 CDD:409353 2/2 (100%)
Ig strand E 296..303 CDD:409353 0/6 (0%)
Ig strand G 322..330 CDD:409353 3/13 (23%)
TIR 389..539 CDD:396246 4/18 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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