Protein Alignment CG8298 and glpK

DIOPT Version :10

• Sequence 1: NP_610718.1
• Gene: CG8298 / 36282
• FlyBaseID: FBgn0033673
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_418361.1
• Gene: glpK / 948423
• ECOCYCID: EG10398
• Length: 502
• Species: Escherichia coli
• Alignment Length: 535
• Identity: 186/535 - (34%)
• Similarity: 271/535 - (50%)
• Gaps: 77/535 - (14%)

  Fly    32 NAEVLAYHELKLRQIVHQAGWMEYDPSEIWKNTQECIETAYKNLVILEINPRDIIAIGIVNQRGT 96
            :|.:::..:.:..||..:.||:|:||.|||. ||.  .|..:.|...:|:...|.||||.|||.|
E. coli    25 DANIISVSQREFEQIYPKPGWVEHDPMEIWA-TQS--STLVEVLAKADISSDQIAAIGITNQRET 86

  Fly    97 SVLWNLETGQPLHNAIGWSDCRSTPILKTLLHNVRHNV-DYVRYRSGLPLSSCFSALKIRWLMDH 160
            :::|..|||:|::|||.| .||.|  .:...|..|..: ||:|..:||.:...||..|::|::||
E. coli    87 TIVWEKETGKPIYNAIVW-QCRRT--AEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDH 148

  Fly   161 VPAVATAIEENKCLFGTLDSWLLWNLTGGVEMGVHSTDITNAHYTSLMNVSTEQWDPKLCQFFRL 225
            |..........:.||||:|:||:|.:|.|   .||.||.|||..|.|.|:.|..||.|:.:...:
E. coli   149 VEGSRERARRGELLFGTVDTWLIWKMTQG---RVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDI 210

  Fly   226 PLNILPRIRSNSEIFGYVLEGPLHGT--PIAAMMGEQPASLLGQLCVKAGQNVCTLDDSCFVLLN 288
            |..:||.:|.:||::|....|...||  ||:.:.|:|.|:|.||||||.|....|....||:|:|
E. coli   211 PREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMN 275

  Fly   289 TGREKLDSANGLITGIAHKLGEKAATNYTLEGAISNAGSTVTWLRDKLQ-INTEINSNDNVVESL 352
            ||.:.:.|.|||:|.||  .|.....||.||||:..||:::.||||::: ||...:|.....:..
E. coli   276 TGEKAVKSENGLLTTIA--CGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQ 338

  Fly   353 NTFIGENSMISSSCSSSMLNAECGLAAKRSEITFVPAFHGMYAPYWRHDARGIILGLTSQTTAEN 417
            ||                           :.:..||||.|:.||||...|||.|.|||....|.:
E. coli   339 NT---------------------------NGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANH 376

  Fly   418 ITQAAYEATGFQIFEVLQAFKRDTPNWDRSSMQPVLTFGGDYAENLHLVQFIADIIGYMLERPQT 482
            |.:|..|:..:|..:||:|.:.|:    ...:..:...||..|.|. |:||.:||:|..:|||:.
E. coli   377 IIRATLESIAYQTRDVLEAMQADS----GIRLHALRVDGGAVANNF-LMQFQSDILGTRVERPEV 436

  Fly   483 TSPAGLGVMITAGVTM------------KVVSLEHAVKMYTPPTDVFSP---TTTKNRRELLYKR 532
            .....||....||:.:            .|:..|            |.|   ||.:|.|   |..
E. coli   437 REVTALGAAYLAGLAVGFWQNLDELQEKAVIERE------------FRPGIETTERNYR---YAG 486

  Fly   533 WAYAVKKCLHWNNYE 547
            |..|||:.:.|..::
E. coli   487 WKKAVKRAMAWEEHD 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8298	NP_610718.1	ASKHA_ATPase-like	19..540	CDD:483947	185/526 (35%)
glpK	NP_418361.1	glpK	1..498	CDD:234594	185/530 (35%)