DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8298 and YTA7

DIOPT Version :9

Sequence 1:	NP_610718.1	Gene:	CG8298 / 36282	FlyBaseID:	FBgn0033673	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_011786.1	Gene:	YTA7 / 853186	SGDID:	S000003502	Length:	1379	Species:	Saccharomyces cerevisiae

Alignment Length:	465	Identity:	77/465 - (16%)
Similarity:	146/465 - (31%)	Gaps:	151/465 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 EIWKNTQECIETAYKNLV-ILEINPRDIIAIGIVNQRGTSVLWNL-------------ETGQPLH 109
            ::.|.::|.|...:.||: :|:..|.||    .:.:|....|..|             |.|:||.
Yeast   896 QLHKPSKENITRYFSNLIELLKTKPSDI----PMKKRRVKPLPELQKVTSNAAPTNFDENGEPLS 956

  Fly   110 NAIGWSDCRSTPILKTLLHNVRHNVDYVRYRSGLPLSSCFSALKIRWLMDHVPAVATAI------ 168
            ..:         :|:..|.:.:|....::....:.||......|.|:.....|.:..|.
Yeast   957 EKV---------VLRRKLKSFQHQDMRLKNVLKIKLSGLMDLFKNRYKRFRKPPIDDAFLVHLFE 1012

  Fly   169 ---------------EENKCLFGTLDSWLLWNLTG----GVEMGVHSTDITNAHYTSLMNVSTEQ 214
                           :||         .:|...||    .:::.:....:.|.:|:
Yeast  1013 PETSNDPNWQPAYIKDEN---------MILEVSTGRKFFNMDLDIVEERLWNGYYS--------- 1059

  Fly   215 WDPKLCQFFRLPLNIL----------PRIRSNSEIFGYVLEGPLHGTPIAAMMGEQPASL--LGQ 267
             :||  ||.: .:.::          .|:...||:|.            .|.||.:..|.  ..|
Yeast  1060 -EPK--QFLK-DIELIYRDANTIGDRERVIKASEMFA------------NAQMGIEEISTPDFIQ 1108

  Fly   268 LC-------------------VKAGQNVCTLDDSCFVLLNTGREKLDSANGLITGIAHKLGEKAA 313
            .|                   .:|...:...:.|...:|.....|.:.||.......::|..:..
Yeast  1109 ECKATRQRDLERQELFLEDEEKRAAMELEAKEQSQENILQEPDLKDNKANEFGVAAGNQLQAQLQ 1173

  Fly   314 TNYTLEGAISNAGSTVTWLRDKLQINTEINSN----------DNVVESLNTFIGENSMISSSCSS 368
            |.......::|:           ::...|::|          .:.|:.....|.|:|..:...::
Yeast  1174 TTINTASIVNNS-----------EVPQPIDTNLYKKEIPAAIPSAVDKEKAVIPEDSGANEEYTT 1227

  Fly   369 SMLNAECGLAAKRSEITFVPAFHGMYAPYWRHDARGIILGLTSQTTAENITQAAYEATGFQIFEV 433
            .::.|.|     .||||..........|....|:      |.:|.|.||.::...........:.
Yeast  1228 ELIQATC-----TSEITTDDDERARKEPKENEDS------LQTQVTEENFSKIDANTNNINHVKE 1281

  Fly   434 LQAFKRDTPN 443
            :|:..:  ||
Yeast  1282 IQSVNK--PN 1289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8298	NP_610718.1	FGGY_GK	12..534	CDD:198347	77/465 (17%)
CG8298	NP_610718.1	glycerol_kin	21..543	CDD:273549	77/465 (17%)
YTA7	NP_011786.1	RecA-like_Yta7-like	414..583	CDD:410925
		SpoVK	430..>882	CDD:223540
		Bromo_TBP7_like	979..1098	CDD:99923	23/152 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900