DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8298 and fggy

DIOPT Version :9

Sequence 1:	NP_610718.1	Gene:	CG8298 / 36282	FlyBaseID:	FBgn0033673	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_998446.2	Gene:	fggy / 406567	ZFINID:	ZDB-GENE-040426-2461	Length:	545	Species:	Danio rerio

Alignment Length:	570	Identity:	115/570 - (20%)
Similarity:	198/570 - (34%)	Gaps:	141/570 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 VHQAGWMEYDPS--EIWKNTQECIETAYKNLVILEINPRDIIAIG--------IVNQRGTSVLWN 101
            ||:.....|:.|  |||   .:|.:|..:  |...::...:..||        :::|:...:..|
Zfish    37 VHEPCVDHYEQSSTEIW---SKCCQTVKR--VTEGVDAACVRGIGFDGTCSLVVLDQQFRPLAVN 96

  Fly   102 LETGQPLHNAIGWSDCRS-------TPILKTLLHNVRHNVDYVRYRSGLPLSSCFSALKIRWLMD 159
            | .|....|.:.|.|.|:       |....|||..|           |..:|......|:.||.:
Zfish    97 L-AGVCDRNVVMWMDHRAAAQASRITACRHTLLQRV-----------GGVMSPEIQPPKLLWLKE 149

  Fly   160 HVPAVATAIEENKCL-----FGTLDSWLLWNLTGGVEMGVHSTDITNAHYTSLMNVSTEQWDPKL 219
            ::|        :.|.     |..|..:|.|..||.:...: .|.:....|:     ::|.||...
Zfish   150 NLP--------DSCWTRAAHFFDLPDFLSWKATGSLSRSL-CTLVCKWTYS-----ASEGWDDTF 200

  Fly   220 CQFFRLPLNI---LPRIRSNSEIFGYVLE-----------GPLHGTPIAAMMGEQPASLLGQLCV 270
            .....|...|   ..||.|.....|..:.           |...||.:.|.:.:..|..:|.|
Zfish   201 WSAIGLEDLIEDSYARIGSQVCCPGAAVGRGLTAAAAADLGLNEGTAVGASLIDAHAGGIGVL-- 263

  Fly   271 KAGQNVCTL------------------DDSCFVLLNTGREKL-------DSANGLITGIAHKLGE 310
              |.:|..|                  ..||.:.::  ||.|       ...:.::.|:....|.
Zfish   264 --GADVSGLHLPCEHQPLTARMALICGTSSCHMAVS--REPLLVPGVWGPYLSAMLPGLWLNEGG 324

  Fly   311 KAATNYTLEGAISNAGSTVTWLRDKLQINTEINSNDNVVESLNTFIGENSMISSSCSSSMLNAEC 375
            ::||...|:..:....:.     .:|:...| :|..::...||..:.:.|..::.
Zfish   325 QSATGKLLDHVVKGHAAF-----RQLEEQAE-HSGRHIYTQLNLHLQQMSTDATH---------- 373

  Fly   376 GLAAKRSEITFVPAFHGMYAPYWRHDARGIILGLTSQTTAENITQAAYEATGFQIFEVLQAFKRD 440
             |....:.:...|.|||..:|.....|||.::||:...|.:::. ..|.||       |||....
Zfish   374 -LEQLTTHLHIWPDFHGNRSPLADQTARGTVVGLSLSQTLDDLA-LLYLAT-------LQALALG 429

  Fly   441 TPNWDRSSMQ-----PVLTFGGDYAENLHLVQFIADIIGYMLERPQTTSPAGLG-VMITAGVTMK 499
            :.:...:..:     ..|...|..::|...||..|:..|..:..|.......|| .:|.|..:..
Zfish   430 SRHIIAAMTEAGHDITTLFLCGGLSKNTLFVQTHANTTGLPVVLPAEREAVLLGAAVIGACASSD 494

  Fly   500 VVSLEHAVKMYTPPTDVFSPTTTKNRRELLYKRWAYAV--------KKCL 541
            ..|:..|::..:....|..|..   ..:..|:| .|:|        |:|:
Zfish   495 CTSIPEAMRKMSRVGRVVRPNP---ELQSFYRR-KYSVFLRLYQHQKECV 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8298	NP_610718.1	FGGY_GK	12..534	CDD:198347	111/553 (20%)
CG8298	NP_610718.1	glycerol_kin	21..543	CDD:273549	115/570 (20%)
fggy	NP_998446.2	FGGY_YpCarbK_like	4..539	CDD:212663	114/567 (20%)
fggy	NP_998446.2	5C_CHO_kinase	5..538	CDD:273552	113/566 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910