DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8298 and Fggy

DIOPT Version :9

Sequence 1:	NP_610718.1	Gene:	CG8298 / 36282	FlyBaseID:	FBgn0033673	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	XP_038965462.1	Gene:	Fggy / 298250	RGDID:	1359429	Length:	558	Species:	Rattus norvegicus

Alignment Length:	570	Identity:	117/570 - (20%)
Similarity:	196/570 - (34%)	Gaps:	169/570 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 VLAYHELKLRQIVHQAGWMEYDPSEIW----KNTQECIE------------TAYKNLVIL--EIN 81
            :||:.|..:::...|....|....:||    :.|:|.::            .|..:||:|  |.:
  Rat    64 LLAFAEQPIKKWEPQFNHHEQSSEDIWAACCRVTKEIVQGIDAHRIRGLGFDATCSLVVLDKEFH 128

  Fly    82 PRDIIAIGIVNQRGTSVLWNLETGQPLHNAIGWSDCRSTPILKTLLHNV---RHNVDYVRYRSGL 143
            |..      ||:.|.|          ..|.|.|.|.|:.    :.:|.:   :|:|  ::|..|:
  Rat   129 PLP------VNREGDS----------SRNIIMWLDHRAV----SQVHRINETKHSV--LQYVGGV 171

  Fly   144 PLSSCFSALKIRWLMDHVPAVATAIEENKCLFGTLDSWLLWNLTGGVEMGVHSTDITNAHYTSLM 208
             :|....|.|:.||.:::..:..   :....|..|..:|.|..||          :|.....||:
  Rat   172 -MSVEMQAPKLLWLKENLREICW---DKAGHFFDLPDFLSWKATG----------VTARSLCSLV 222

  Fly   209 ---NVSTEQ-WDPKLCQFFRLPLNILPRIRSNSEIFGYVLEGP------------------LHGT 251
               ..|.|: ||.   .|::: :.:...|..|....|.::..|                  ..|.
  Rat   223 CKWTYSAEKGWDD---SFWKM-IGLEDLIGDNYNKIGNLVLPPGASLGSGLIPEAARELGLPSGI 283

  Fly   252 PIAAMMGEQPASLLG--------------------QLCVKAGQNVCTL---DDSCFVLLNTGREK 293
            .:||.:.:..|..||                    :|.|..|.:.|.:   .|..||
  Rat   284 AVAASLIDAHAGGLGVIGADVRGHGLTCEGQPVTSRLAVICGTSSCHMGISKDPIFV-------- 340

  Fly   294 LDSANGLITGIAHKLGEKAATNYTL-EGAISNAGSTVTWLRDKLQINTEINSNDNVVESLNTFIG 357
                    .|:...........:.| ||..|..|..:                |::|:|...|..
  Rat   341 --------PGVWGPYFSAMVPGFWLNEGGQSVTGKLI----------------DHMVQSHPAFPE 381

  Fly   358 ENSMISSSCSS--SMLNAECGLAAKRSEITFV-------PAFHGMYAPYWRHDARGIILGLTSQT 413
            ..:..::.|.|  :.||:...|..|...:.|:       |.|||..:|......:|::.|||...
  Rat   382 LQAKATARCQSIYAYLNSHLDLIKKAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLTLSR 446

  Fly   414 TAENIT-------QAAYEATGFQIFEVLQAFKRDTPNWDRSSMQPVLTFGGDYAENLHLVQFIAD 471
            ..:::.       ||....|.| |.|.::|...        |:..:...|| .::|...||..||
  Rat   447 DLDDLAVLYLATIQAIAFGTRF-IIETMEAAGH--------SLSTLFLCGG-LSKNPLFVQMHAD 501

  Fly   472 IIGYMLERPQTTSPAGLGVMI----TAGVTMKVVSLEHAVKMYTPPTDVF 517
            |.|..:...|......:|..|    .:|....|.:.|...:..:..||.|
  Rat   502 ITGMPVVLSQEVESVLVGAAILGACASGDFASVQTGESLPETCSVVTDFF 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8298	NP_610718.1	FGGY_GK	12..534	CDD:198347	117/570 (21%)
CG8298	NP_610718.1	glycerol_kin	21..543	CDD:273549	117/570 (21%)
Fggy	XP_038965462.1	FGGY_YpCarbK_like	41..536	CDD:212663	113/553 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810