DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8298 and ATAD2

DIOPT Version :9

Sequence 1:	NP_610718.1	Gene:	CG8298 / 36282	FlyBaseID:	FBgn0033673	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_054828.2	Gene:	ATAD2 / 29028	HGNCID:	30123	Length:	1390	Species:	Homo sapiens

Alignment Length:	181	Identity:	38/181 - (20%)
Similarity:	67/181 - (37%)	Gaps:	43/181 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 NILPRIRSNSEIFGYVLEGP-------LHGTPIAAMMGEQPASLLGQLCVKAGQNVCTLDDSCFV 285
            :::|  :.||.:.|.....|       ...||:|.   ..||.|..::..|:...:.|:..
Human  1124 HVMP--KQNSTLVGDKRSDPEQNEKLKTPSTPVAC---STPAQLKRKIRKKSNWYLGTIKK---- 1179

  Fly   286 LLNTGREKL-----DSANGLITGIAHKLGEKAATNYTLEGAI-----SNAGSTVTWLRDKLQ--- 337
                 |.|:     ||.|    .|.||:  ::.|..|.:.::     .|.|.:.....:|.|
Human  1180 -----RRKISQAKDDSQN----AIDHKI--ESDTEETQDTSVDHNETGNTGESSVEENEKQQNAS 1233

  Fly   338 -INTEINSNDNVVESLNTFIGENSMISSSCSSSMLNAECGLAAKRSEITFV 387
             ...|:.:|.|.....|..  |:|..:::|:.......|...|..|:|..:
Human  1234 ESKLELRNNSNTCNIENEL--EDSRKTTACTELRDKIACNGDASSSQIIHI 1282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8298	NP_610718.1	FGGY_GK	12..534	CDD:198347	38/181 (21%)
CG8298	NP_610718.1	glycerol_kin	21..543	CDD:273549	38/181 (21%)
ATAD2	NP_054828.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..63
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	216..380
		AAA	459..600	CDD:214640
		AAA	464..598	CDD:278434
		COG5076	<915..1153	CDD:227408	5/30 (17%)
		Bromo_AAA	987..1097	CDD:99957
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1124..1163		10/43 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1181..1242		14/66 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900