Protein Alignment CG8298 and GK5

DIOPT Version :10

• Sequence 1: NP_610718.1
• Gene: CG8298 / 36282
• FlyBaseID: FBgn0033673
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_001034636.1
• Gene: GK5 / 256356
• HGNCID: 28635
• Length: 529
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 147/557 - (26%)
• Similarity: 252/557 - (45%)
• Gaps: 69/557 - (12%)

  Fly    10 GALIGVACVSSTHCRFLIYSTKNAEVLAYHELKLRQIVHQAGWMEYDPSEIWKNTQECIETAYKN 74
            |.::|:. |.|:..|..:|. :.|.|......|:..:..|.||:|.||..:|......|:.|.|
Human    19 GFVLGLD-VGSSVIRCHVYD-RAARVCGSSVQKVENLYPQIGWVEIDPDVLWIQFVAVIKEAVK- 80

  Fly    75 LVILEINPRDIIAIGIVNQRGTSVLWNLETGQPLHNAIGWSDCRSTPILK----TLLHNVRHN-- 133
              ...|....|:.:||..||.|.:.||.:||...||.|.|.|.|:..::|    :||..:.|:
Human    81 --AAGIQMNQIVGLGISTQRATFITWNKKTGNHFHNFISWQDLRAVELVKSWNNSLLMKIFHSSC 143

  Fly   134 --VDYVRYRSGLPLSSCF------SALKIRWLMDHVPAVATAIEENKCLFGTLDSWLLWNLTGGV 190
              :.:......|..:|.|      ::|::.|::.::..|..|:||..|.|||:|:|||:.||.|
Human   144 RVLHFFTRSKRLFTASLFTFTTQQTSLRLVWILQNLTEVQKAVEEENCCFGTIDTWLLYKLTKG- 207

  Fly   191 EMGVHSTDITNAHYTSLMNVSTEQWDPKLCQFFRLPLNILPRIRSNSEIFGYVLEGPLHGT--PI 253
              .|::||.:||..|.|.:.....|...:.....:||::||.:|..|..||.|.| .:.|.  ||
Human   208 --SVYATDFSNASTTGLFDPYKMCWSGMITSLISIPLSLLPPVRDTSHNFGSVDE-EIFGVPIPI 269

  Fly   254 AAMMGEQPASLLGQLCVKAGQNVCTLDDSCFVLLNTGREKLDSANGLITGIAHKLGEKAATNYTL 318
            .|::.:|.:::.|:.|.:.|....|:....|:.:|||.....:..|....|..|:|::....
Human   270 VALVADQQSAMFGECCFQTGDVKLTMGTGTFLDINTGNSLQQTTGGFYPLIGWKIGQEVVCL--- 331

  Fly   319 EGAISNAGSTVTWLR--DKLQINTEINSNDNVVESLNTFIGENSMISSSCSSSMLNAECGLAAKR 381
              |.||||.|.|.::  .:|.:.|:....:.:.:||....|
Human   332 --AESNAGDTGTAIKWAQQLDLFTDAAETEKMAKSLEDSEG------------------------ 370

  Fly   382 SEITFVPAFHGMYAPY---WRHDARGIILGLTSQTTAENITQAAYEATGFQIFEVLQAFKRDTPN 443
              :.|||:|.|:.||.   |   |....:||...|:..::.:|..|:..|:..::.:..|::.
Human   371 --VCFVPSFSGLQAPLNDPW---ACASFMGLKPSTSKYHLVRAILESIAFRNKQLYEMMKKEI-- 428

  Fly   444 WDRSSMQPVLTFGGDYAENLHLVQFIADIIGYMLERPQTTSPAGLGVMITAGVTMKVVSLEHAVK 508
              ...::.:...|| ..:|..::|..:|:|...::||.....:.||....||:.:...:.:..:|
Human   429 --HIPVRKIRADGG-VCKNGFVMQMTSDLINENIDRPADIDMSCLGAASLAGLAVGFWTDKEELK 490

  Fly   509 MYTPPTDVFSPTTTKNRRELLYKRWAYAVKKCLHWNN 545
            .......||.|.......|:..:.||.|||:.::|.|
Human   491 KLRQSEVVFKPQKKCQEYEMSLENWAKAVKRSMNWYN 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8298	NP_610718.1	ASKHA_ATPase-like	19..540	CDD:483947	142/541 (26%)
GK5	NP_001034636.1	ASKHA_NBD_FGGY_GK5-like	20..520	CDD:466803	142/547 (26%)