DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8298 and Psmc2

DIOPT Version :9

Sequence 1:	NP_610718.1	Gene:	CG8298 / 36282	FlyBaseID:	FBgn0033673	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_001355590.1	Gene:	Psmc2 / 19181	MGIID:	109555	Length:	433	Species:	Mus musculus

Alignment Length:	224	Identity:	44/224 - (19%)
Similarity:	69/224 - (30%)	Gaps:	100/224 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 TAIEENKCLFGTLDSWL----LWNLTGGVEMGVHSTDITNAHYTSLMNVSTEQWDPK----LCQF 222
            |.|:|:       |:.|    ||:|....:.......:..|..|.::|..:|  |||    :.||
Mouse    63 TGIKES-------DTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSE--DPKYIINVKQF 118

  Fly   223 FR--------------------------------LPLNILPRIR----------SNSEIFG---- 241
            .:                                ||..|.|.:.          :.|::.|
Mouse   119 AKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQ 183

  Fly   242 -----YVLEGP-LHGTPIAAMMGEQPASLL-------GQ-LCVKAGQNVCTLDDSCFVLLNTGRE 292
                 .|:|.| ||......:..|.|..:|       |: ||.:|   |....|:||:.:
Mouse   184 IEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARA---VANRTDACFIRV----- 240

  Fly   293 KLDSANGLITGIAHKLGEKAATNYTLEGA 321
                           :|.:....|..|||
Mouse   241 ---------------IGSELVQKYVGEGA 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8298	NP_610718.1	FGGY_GK	12..534	CDD:198347	44/224 (20%)
CG8298	NP_610718.1	glycerol_kin	21..543	CDD:273549	44/224 (20%)
Psmc2	NP_001355590.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
Psmc2	NP_001355590.1	RPT1	23..430	CDD:224143	44/224 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900