DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8298 and gk

DIOPT Version :9

Sequence 1:	NP_610718.1	Gene:	CG8298 / 36282	FlyBaseID:	FBgn0033673	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	XP_012811696.1	Gene:	gk / 100038285	XenbaseID:	XB-GENE-961541	Length:	562	Species:	Xenopus tropicalis

Alignment Length:	603	Identity:	222/603 - (36%)
Similarity:	324/603 - (53%)	Gaps:	77/603 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GALIGVACVSSTHCRFLIYSTKNAEVLAYHELKLRQIVHQAGWMEYDPSEIWKNTQECIETAYKN 74
            |.|:|.....::..|||:::.|.||:|::|:::::|...:.||:|.||.||.::..||:|...:.
Frog    10 GPLVGAIDQGTSSTRFLVFNAKTAELLSHHQVEIKQKFPKEGWVEQDPKEILQSVYECVEKTCEK 74

  Fly    75 LVILEINPRDIIAIGIVNQRGTSVLWNLETGQPLHNAIGWSDCRSTPILKTLLHNV-RHNVDYVR 138
            |..|.|:..:|.|||:.|||.|:|:|:..||:||:||:.|.|.|:...::.||..: ..|.::.:
Frog    75 LTQLNIDITNIKAIGVSNQRETTVVWDKTTGEPLYNAVVWLDLRTQSTVERLLKRIPGKNKNFFK 139

  Fly   139 YRSGLPLSSCFSALKIRWLMDHVPAVATAIEENKCLFGTLDSWLLWNLTGGVEMGVHSTDITNAH 203
            .|:|||||:.|||:|||||:|:|..:..|:.|.:.:|||:|||::|:|||....|||.||:|||.
Frog   140 SRTGLPLSTYFSAVKIRWLLDNVEEIRHAVSEGRAMFGTVDSWIIWSLTGAKNGGVHCTDVTNAS 204

  Fly   204 YTSLMNVSTEQWDPKLCQFFRLPLNILPRIRSNSEIFGY------VLEGPLHGTPIAAMMGEQPA 262
            .|.|.|:.|.:||.:|||||.:|:.:||::||:|||:|.      :..|.|.|.||:..:|:|.|
Frog   205 RTMLFNIHTLEWDTELCQFFDIPMELLPKVRSSSEIYGLMKICPSLKSGALTGVPISGCLGDQSA 269

  Fly   263 SLLGQLCVKAGQNVCTLDDSCFVLLNTGREKLDSANGLITGIAHKLGEKAATNYTLEGAISNAGS 327
            :|:||:|.:.||...|....||:|.|||.:.:.|.:||:|.:|:|||......|.|||:::.||:
Frog   270 ALVGQMCFQDGQAKNTYGTGCFLLCNTGSKPVLSEHGLLTTVAYKLGRDKPACYALEGSVAIAGA 334

  Fly   328 TVTWLRDKLQI--NTEINSNDNVVESLNTFIGENSMISSSCSSSMLNAECGLAAKRSEITFVPAF 390
            .|.||||.|.|  .||      .||.|...:|    .|..|                  .|||||
Frog   335 VVRWLRDNLGIVKTTE------EVEKLAAEVG----TSYGC------------------YFVPAF 371

  Fly   391 HGMYAPYWRHDARGIILGLTSQTTAENITQAAYEATGFQIFEVLQAFKRDTPNWDRSSMQPV--L 453
            .|:|||||...|||||.|||..|...:|..||.||..||..|:|.|..:|..       .|:  |
Frog   372 SGLYAPYWEPSARGIICGLTQFTNRNHIAFAALEAVCFQTREILDAMNKDCG-------IPLNQL 429

  Fly   454 TFGGDYAENLHLVQFIADIIGYMLERPQTTSPAGLGVMITAGVT--MKVVSLEHAVKMYTPPTDV 516
            ...|....|..|:|..|||:...:.:|.......||..:.||..  :.|.||.        |.|:
Frog   430 QVDGGMTSNKILMQLQADILCIPVVKPSMPETTALGAAMAAGAAEGVGVWSLN--------PGDL 486

  Fly   517 -------FSPTTTKNRRELLYKRWAYAVKKCLHWNNYE--TYEADIELFAQRELDPNLPVRRSVP 572
                   |.|.......|..|.||..||.|.:.|.:.|  ....|..:|.            |:|
Frog   487 TAVTCERFEPQINPEESEFRYARWKKAVMKSMGWESAEPTNGNGDCSIFC------------SLP 539

  Fly   573 GSIFLTTSFAMIILANYL 590
            ...::.:|..::|.|.|:
Frog   540 LGFYIVSSMVLLIGAKYI 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8298	NP_610718.1	FGGY_GK	12..534	CDD:198347	207/541 (38%)
CG8298	NP_610718.1	glycerol_kin	21..543	CDD:273549	209/541 (39%)
gk	XP_012811696.1	FGGY_GK1-3_metazoa	11..520	CDD:212664	211/551 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352321at33208
OrthoFinder	1	1.000	-	-		FOG0001035
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10196
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020