DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-7 and rhbdf1a

DIOPT Version :9

Sequence 1:	NP_001286324.1	Gene:	rho-7 / 36281	FlyBaseID:	FBgn0033672	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	XP_005164392.1	Gene:	rhbdf1a / 798402	ZFINID:	ZDB-GENE-040704-75	Length:	893	Species:	Danio rerio

Alignment Length:	228	Identity:	42/228 - (18%)
Similarity:	76/228 - (33%)	Gaps:	71/228 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 LCNLVAFAMWRVPALKSTMITYFTSNPAAKVVCWPMFLSTFSHYSAMHLFANMYVMHSFANAAAV 217
            :|.|:.|.                 ||......:.::||.|.|...:|...::....:.......
Zfish   676 VCGLLPFL-----------------NPEVPDQFYRLWLSLFLHAGILHCLVSVCFQMTILRDLEK 723

  Fly   218 SLGKEQFLAVYLSAGVFSSLMSVL---YKAATSQAGMSLGASGAIMT-------LLAYVCTQYPD 272
            ..|..:...:|:.:|:..:|.|.:   |:|....||...|....:..       :||.....:..
Zfish   724 LAGWLRISIIYILSGITGNLASAIFLPYRAEVGPAGSQFGILACLFVELIQSWQILAQPWRAFTK 788

  Fly   273 TQLSILFLPALTFSAGAGIKVLMGIDFAGVVMGWKFFDHAAHLGGAMFGIF-------WATYG-A 329
            ....:|||                  ||..::.|  .|:.||:.|.:.|.|       :.::| .
Zfish   789 LLCVVLFL------------------FAFGLLPW--IDNFAHISGFISGFFLSFAFLPYISFGRL 833

  Fly   330 QIWAKR----------IGL------LNYYHDLR 346
            .::.||          :||      |.|.|.::
Zfish   834 DMYRKRCQIIIFLVVFLGLFAGLVVLFYVHPIK 866

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-7	NP_001286324.1	Rhomboid	186..327	CDD:396315	29/157 (18%)
rhbdf1a	XP_005164392.1	Rhomboid_SP	130..347	CDD:289371
		Rhomboid	685..826	CDD:279958	30/160 (19%)
		DUF805	<792..864	CDD:294752	19/91 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900