Protein Alignment rho-7 and RHBDL2

DIOPT Version :10

• Sequence 1: NP_523704.1
• Gene: rho-7 / 36281
• FlyBaseID: FBgn0033672
• Length: 351
• Species: Drosophila melanogaster
• Sequence 2: NP_001291675.1
• Gene: RHBDL2 / 54933
• HGNCID: 16083
• Length: 383
• Species: Homo sapiens
• Alignment Length: 222
• Identity: 40/222 - (18%)
• Similarity: 70/222 - (31%)
• Gaps: 61/222 - (27%)

  Fly   153 LCNLVAFAMWRVPALKSTMIT-----YFTSNPAAKVVCWPMFLSTFSHYSAMHLFANMYV----- 207
            |...:.:|:|:......|:.|     .|..:|..:...|........|....|:..|:.:
Human   163 LAVFIYYAVWKPQKQWITLDTGILESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLG 227

  Fly   208 --MHSFANAAAVSLGKEQFLAVYLSAGVFSSLMSVLYKAATSQAGMSLGASGAIMTLLA----YV 266
              :........|.|       |||:..:..||.|.::    ......:||||.:..|:.    .|
Human   228 IPLEMVHKGLRVGL-------VYLAGVIAGSLASSIF----DPLRYLVGASGGVYALMGGYFMNV 281

  Fly   267 CTQYPDTQLSILFLPALTFSAGAGIKVLMGIDFAGVVMGWKFF--------DHAAHLGGAMFGI- 322
            ...:.:      .:||........|.:::.:|. |..:..:||        ..|||:.|...|:
Human   282 LVNFQE------MIPAFGIFRLLIIILIIVLDM-GFALYRRFFVPEDGSPVSFAAHIAGGFAGMS 339

  Fly   323 ------------------FWATYGAQI 331
                              ||....|.:
Human   340 IGYTVFSCFDKALLKDPRFWIAIAAYL 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rho-7	NP_523704.1	Rhomboid	186..327	CDD:426384	32/178 (18%)
RHBDL2	NP_001291675.1	Rhomboid	194..346	CDD:426384	31/169 (18%)