DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-7 and stet

DIOPT Version :9

Sequence 1:	NP_001286324.1	Gene:	rho-7 / 36281	FlyBaseID:	FBgn0033672	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	222	Identity:	47/222 - (21%)
Similarity:	73/222 - (32%)	Gaps:	54/222 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 ILLCNLVAFAMW------------RVPALKSTMITYFTSNPAAKVVCWPMFLSTFSHYSAMHLFA 203
            |:|..||....:            |.|....:|..|   .|..:...|........|...:||..
  Fly   225 IILVTLVELGFFVYHSVVTGEAAPRGPIPSDSMFIY---RPDKRHEIWRFLFYMVLHAGWLHLGF 286

  Fly   204 NMYVMHSFANAAAVSLGKEQFLAVYLSAGVFSSLMSVLYKAATSQAGMSLGASGAIMTLLAYVCT 268
            |:.|...|.....:..|..:...:|.|..:..||.:.::.......|.|.|....:...||.|..
  Fly   287 NVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVLL 351

  Fly   269 QYPDTQLSIL----FLPALTFSAG-------AGIKVLMG----------IDFAGVVMGWKFFDHA 312
            .|...:..::    .|..::|..|       ||.::.:|          .:.||.|      .:.
  Fly   352 NYHQMRYGVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAV------SYV 410

  Fly   313 AHLGGAMFGIFWATYGAQIWAKRIGLL 339
            |||.||:.|:            .||||
  Fly   411 AHLAGAIAGL------------TIGLL 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-7	NP_001286324.1	Rhomboid	186..327	CDD:396315	34/161 (21%)
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	39/182 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444959
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830