DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-7 and Parl

DIOPT Version :9

Sequence 1:	NP_001286324.1	Gene:	rho-7 / 36281	FlyBaseID:	FBgn0033672	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_001005767.1	Gene:	Parl / 381038	MGIID:	1277152	Length:	377	Species:	Mus musculus

Alignment Length:	298	Identity:	136/298 - (45%)
Similarity:	195/298 - (65%)	Gaps:	28/298 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 TPVPVNNVIKAVAFTGAFTVGC-FAGATILEYENTRSLI-----------LEKARQARFGWWQSR 119
            :|.|:..::|...||..|| || |..|.|.:||:.:|.:           |:..|..:.|
Mouse    89 SPYPIRTLVKPFFFTIGFT-GCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEG----- 147

  Fly   120 SLADRDYWTQIKQDIRRHWDSLTPGDKMFAPILLCNLVAFAMWRVPALKSTMITYFTSNPAAKVV 184
                     .::::|.:.|:||:.|.:....|:..|.:.|.:||||:|:.|||.|||||||:||:
Mouse   148 ---------NLRKEINKWWNSLSDGQRTVTGIIAANALVFCLWRVPSLQRTMIRYFTSNPASKVL 203

  Fly   185 CWPMFLSTFSHYSAMHLFANMYVMHSFANAAAVSLGKEQFLAVYLSAGVFSSLMSVLYKAATSQA 249
            |.||.||||||:|..|:.|||||:.||:::....||:|||:||||||||.|:.:|.:.|.||.:.
Mouse   204 CSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFVAVYLSAGVISNFVSYVCKVATGRY 268

  Fly   250 GMSLGASGAIMTLLAYVCTQYPDTQLSILFLPALTFSAGAGIKVLMGIDFAGVVMGWKFFDHAAH 314
            |.||||||||||:||.|||:.|:.:|:|:|||..||:||..:|.::.:|.||:::||||||||||
Mouse   269 GPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPVFTFTAGNALKAIIAMDTAGMILGWKFFDHAAH 333

  Fly   315 LGGAMFGIFWATYGAQ-IWAKRIGLLNYYHDLRRTKQK 351
            ||||:|||::.|||.: ||..|..|:..:|::|....|
Mouse   334 LGGALFGIWYITYGHELIWKNREPLVKIWHEIRTNGPK 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-7	NP_001286324.1	Rhomboid	186..327	CDD:396315	82/140 (59%)
Parl	NP_001005767.1	Rhomboid	207..348	CDD:279958	83/140 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834990
Domainoid	1	1.000	179	1.000	Domainoid score	I3529
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10239
Inparanoid	1	1.050	268	1.000	Inparanoid score	I3013
Isobase	1	0.950	-	0	Normalized mean entropy	S2377
OMA	1	1.010	-	-		QHG45264
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005057
OrthoInspector	1	1.000	-	-		oto93582
orthoMCL	1	0.900	-	-		OOG6_101864
Panther	1	1.100	-	-	LDO	PTHR43731
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1980
SonicParanoid	1	1.000	-	-		X3580
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740