DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-7 and Rhbdl3

DIOPT Version :9

Sequence 1:	NP_001286324.1	Gene:	rho-7 / 36281	FlyBaseID:	FBgn0033672	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	XP_006533389.1	Gene:	Rhbdl3 / 246104	MGIID:	2179276	Length:	433	Species:	Mus musculus

Alignment Length:	251	Identity:	56/251 - (22%)
Similarity:	87/251 - (34%)	Gaps:	56/251 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 NTRSLILEKARQARFGWWQSRSLADRDYWTQIKQDIRRHW--DSLT--PGDKMFAPILLCNLVAF 159
            ::::|:.||      |...|:.|.....:..:.::|.|.|  ||.|  |.......|.|..:..|
Mouse   119 SSKALLEEK------GLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITITLLEVALF 177

  Fly   160 AMWRVPALKSTMITYFTSNPAAKVVCWPMFL-STFSHYSAMHLFANMYVMHSFANAAAVSLGKE- 222
                  .....::..|...     |..|.:| ::..::..:...|..||.:.|.:|....||..
Mouse   178 ------LYNGVLLDQFVLQ-----VTHPRYLKNSLVYHPQLRAQAWRYVTYIFMHAGVEQLGLNV 231

  Fly   223 --QFLA---------------VYLSAGVFSSLM--SVLYKAATSQAGMSLGASGAIMTLLAYVCT 268
              |.|.               ||: |||.:.|:  .|..:||....|:.|...|.....:|
Mouse   232 ALQLLVGVPLEMVHGATRIGLVYV-AGVVAELVRHEVPVQAAADGCGLDLYEYGVRKGCMA---- 291

  Fly   269 QYPDTQLSILFLPALT---------FSAGAGIKVLMGIDFAGVVMGWKFFDHAAHL 315
            .:|...||.:..|.|.         ...|.|....:..:.||.|......||..||
Mouse   292 PFPPIGLSPVPPPKLCGTLGWRGRGHHPGRGGSQKLRAEAAGPVAVVDLCDHVHHL 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-7	NP_001286324.1	Rhomboid	186..327	CDD:396315	38/160 (24%)
Rhbdl3	XP_006533389.1	EF-hand_7	36..100	CDD:372618
Rhbdl3	XP_006533389.1	Rhomboid	207..>260	CDD:389796	14/53 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900