Protein Alignment RnrS and RRM2B

DIOPT Version :10

• Sequence 1: NP_525111.1
• Gene: RnrS / 36280
• FlyBaseID: FBgn0011704
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001165948.1
• Gene: RRM2B / 50484
• HGNCID: 17296
• Length: 423
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 255/349 - (73%)
• Similarity: 297/349 - (85%)
• Gaps: 3/349 - (0%)

  Fly    45 AKESSTVNGIGKSANSLMEKSVTPFDPSLEPLLRENPRRFVIFPIQYHDIWQMYKKAEASFWTVE 109
            ||:.:.....|:|::...|..:...:   |||||::.||||||||||.|||:|||:|:|||||.|
Human    78 AKDDAWRPQAGRSSSDTNESEIKSNE---EPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAE 139

  Fly   110 EVDLSKDLTDWHRLKDDERHFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMEN 174
            ||||||||..|::||.||::||||:||||||||||||||||||||||||:.||||||||||.:||
Human   140 EVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIEN 204

  Fly   175 VHSEMYSVLIDTYIRDPHQREYLFNAIETMPAVKRKADWALSWISSKSANFGERIIAFAAVEGIF 239
            |||||||:|||||||||.:||:|||||||||.||:||||||.||:.:.:.||||::|||||||:|
Human   205 VHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVF 269

  Fly   240 FSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFAVLMFQHLVQRPKRERIIEIIRDAVAIE 304
            ||||||:|||||||||||||||||||||||||||||||.||||:||.:|..||:.|||.|||.||
Human   270 FSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIE 334

  Fly   305 QEFLTDALPVNLIGMNCDLMSQYIEFVADRLLVELGVGKIYNTKNPFNFMEMISLDGKTNFFEKK 369
            |||||:||||.||||||.||.|||||||||||||||..|::..:|||:|||.|||:||||||||:
Human   335 QEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKR 399

  Fly   370 VGEYQRMGVVSNPLDNVFTLDADF 393
            |.||||..|::...||||||||||
Human   400 VSEYQRFAVMAETTDNVFTLDADF 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RnrS	NP_525111.1	Ferritin_like	74..393	CDD:469698	248/318 (78%)
RRM2B	NP_001165948.1	Ferritin_like	104..423	CDD:469698	248/318 (78%)