Protein Alignment GalT1 and B3GNT5

DIOPT Version :10

• Sequence 1: NP_788328.1
• Gene: GalT1 / 36279
• FlyBaseID: FBgn0053145
• Length: 466
• Species: Drosophila melanogaster
• Sequence 2: NP_114436.1
• Gene: B3GNT5 / 84002
• HGNCID: 15684
• Length: 378
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 99/345 - (28%)
• Similarity: 159/345 - (46%)
• Gaps: 74/345 - (21%)

  Fly   126 KDFCR-NKTFLVIAVCTGVDNFIQRHTIRETWGNTTEFNYPAFGKLHGHLKGHYLPPLPDRLKMY 189
            |:.|: ....|::.|.|..:|:.:|..||.||||.   ||..
Human    80 KEKCQAQDVLLLLFVKTAPENYDRRSGIRRTWGNE---NYVR----------------------- 118

  Fly   190 GDYLSGEGQSLTASVRIVFIVGRQKDEAMLGNETLNRIHIESEKYNDIIQENFVDSYNNLTLKSV 254
                    ..|.|:::.:|.:|  ....:.|.|...::..|.::||||||::||||:.|||||.:
Human   119 --------SQLNANIKTLFALG--TPNPLEGEELQRKLAWEDQRYNDIIQQDFVDSFYNLTLKLL 173

  Fly   255 MALKHISRSCFNTAVYFLKCDDDTFVNIPNLLNFLLGGTIPLYNDTLDYHDRSTYLVTAPQTRLK 319
            |.....:..|.: |.:.:..|||.|:::|||:.                     ||.:..|..::
Human   174 MQFSWANTYCPH-AKFLMTADDDIFIHMPNLIE---------------------YLQSLEQIGVQ 216

  Fly   320 ASSDVLYGHQFCNVVPVSEVSSKWYMPSYMYKPESYPKYLSGAGYLMSIDVVQRLFEAS--LNTT 382
               |...|.......|:.:.|||:|:...||:..:||.|.:||.|::|.||..:::|||  ||::
Human   217 ---DFWIGRVHRGAPPIRDKSSKYYVSYEMYQWPAYPDYTAGAAYVISGDVAAKVYEASQTLNSS 278

  Fly   383 LVYLEDVYITGLCAQKAKINRHHHPLFSFAHSK---QMCAFKGTITQHQLKDDSMVSAWNYVSNY 444
            | |::||:: ||||.|..|....|..|| ...|   ..|.::..:|.|...:| :...|...::.
Human   279 L-YIDDVFM-GLCANKIGIVPQDHVFFS-GEGKTPYHPCIYEKMMTSHGHLED-LQDLWKNATDP 339

  Fly   445 SIKCPPPGRYFSQV--RLRK 462
            .:|....| :|.|:  ||.|
Human   340 KVKTISKG-FFGQIYCRLMK 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GalT1	NP_788328.1	Galactosyl_T	204..407	CDD:473923	66/204 (32%)
B3GNT5	NP_114436.1	Galactosyl_T	102..299	CDD:473923	77/259 (30%)