DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GalT1 and CG11357

DIOPT Version :9

Sequence 1:	NP_788328.1	Gene:	GalT1 / 36279	FlyBaseID:	FBgn0053145	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001097505.1	Gene:	CG11357 / 38561	FlyBaseID:	FBgn0035558	Length:	434	Species:	Drosophila melanogaster

Alignment Length:	446	Identity:	111/446 - (24%)
Similarity:	176/446 - (39%)	Gaps:	116/446 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LAAEYSSSSGAAASGSEDETVTTSGALRSKAKLRKRQLRNRMPLPRMLRRLGCYTLSAFLICGLL 81
            :.|::|.|.|.::|.:.....:....||     |.|...|::..|   .|....:..:.|:...
  Fly    34 IIADFSGSGGISSSSTAQPPTSAKSGLR-----RSRSQPNQIHQP---SRTPSNSNDSSLVSNT- 89

  Fly    82 LVYLPLVYLDVHKRSAGLPDWTSET---SRSIADYLDIGLSSGVIVPKDFCRNKTFLVIAVCTGV 143
                    .|.|..... |...|:|   .:|....:|:. :...::.:..|......:|.|.:.|
  Fly    90 --------FDNHPMGTP-PTLASQTPTPPQSSMHLMDLP-NFVYLIDQPACDKDVRALILVHSAV 144

  Fly   144 DNFIQRHTIRETWGNTTEFNYPAFGKLHGHLKGHYLPPLPDRLKMYGDYLSGEGQSLTASVRIVF 208
            .|..:|..|||||.|.:                 |:...|  ||:|                  |
  Fly   145 RNIEKRRIIRETWANRS-----------------YIDQTP--LKVY------------------F 172

  Fly   209 IVG-----RQKDEAMLGNETLNRIHIESEKYNDIIQENFVDSYNNLTLKSVMALKHISRSCFNTA 268
            :||     .:|.:..||.|  |.:|      .|:||.||.|:|.|:|.|.|||||..:..|.: |
  Fly   173 LVGGVSAKSEKWQQFLGRE--NHLH------GDLIQGNFKDAYRNMTYKHVMALKWFNEKCAH-A 228

  Fly   269 VYFLKCDDDTFVNIPNLLNFLLGGTIPLYNDTLDYHDRSTYLVTAPQTRLKASSDVLYGHQFCNV 333
            ...:|.|||.|:|.|.|:.:|...::|.|:           ::..|...|            |..
  Fly   229 QLLVKVDDDVFMNTPQLVKYLATPSLPEYS-----------MLRDPNLML------------CRS 270

  Fly   334 VPVSEVS----SKWYMPSYMYKPESYPKYLSGAGYLMSIDVVQRLFEASLNTTLVYLEDVYITGL 394
            |..|.|.    |||.:....|....||:|..|...:.:.:||:||:||:..:...:::||.|||:
  Fly   271 VHHSRVKRSYRSKWRVTYKEYPNRFYPEYCPGMAIVYAPEVVRRLYEAAQKSKYFWVDDVLITGI 335

  Fly   395 CAQK--AKINRHHHPLFSFAHSKQMCAFKG----------TITQHQLKDDSMVSAW 438
            .|::  :||.    ||..:...|.:....|          ..|.|.:|.|..::.|
  Fly   336 LAEETGSKIT----PLQHYLEQKDVRKLVGGEADLEDPPFLFTNHAIKPDESMTIW 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GalT1	NP_788328.1	Galactosyl_T	204..407	CDD:304462	65/213 (31%)
CG11357	NP_001097505.1	Galactosyl_T	148..347	CDD:304462	77/271 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I2616
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4848
orthoMCL	1	0.900	-	-		OOG6_100261
Panther	1	1.100	-	-	P	PTHR11214
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
	8	7.870