DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GalT1 and CG8673

DIOPT Version :9

Sequence 1:	NP_788328.1	Gene:	GalT1 / 36279	FlyBaseID:	FBgn0053145	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_609182.1	Gene:	CG8673 / 34105	FlyBaseID:	FBgn0031986	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	438	Identity:	106/438 - (24%)
Similarity:	187/438 - (42%)	Gaps:	112/438 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 SGAAASGSEDETVTTSG---------ALRSK----AKLRKRQLRNRMPLPRMLRRLGCYTLSAFL 76
            ||.::.|::|...|..|         |:||:    .||....|.::..|.:  :.:..|::..
  Fly    77 SGNSSEGNKDIYTTIDGNINVADSIAAIRSRRIDEEKLHDDGLDSKDILAK--KSVVLYSIDT-- 137

  Fly    77 ICGLLLVYLPLVYLDVHKRSAGLPDWTSETSRSIADYLDIGLSSGVIVPKDFCRNKTFLVIAVCT 141
               .:.|.:||| ..::|                ..:||..:....|.|:...  .|.|::.:.:
  Fly   138 ---EVPVRMPLV-KTIYK----------------PGHLDSEIDMERICPQKGL--STQLLVLITS 180

  Fly   142 GVDNFIQRHTIRETWGNTTEFNYPAFGKLHGHLKGHYLPPLPDRLKMYGDYLSGEGQSLTASVRI 206
            .:.:...|.:||:||             :|                 ||.         ...|.:
  Fly   181 SLRHSAARMSIRQTW-------------MH-----------------YGS---------RRDVGM 206

  Fly   207 VFIVGRQKDEAMLGNETLNRIHIESEKYNDIIQENFVDSYNNLTLKSVMALKHISRSCFNTAVYF 271
            .|::|:.|::::     ...|..|...|.|:|:.:|:|||||||||::..|:.....| ..|.|.
  Fly   207 AFVLGKGKNKSV-----KKAIDQEDFMYQDLIRGHFIDSYNNLTLKTISLLEWADLHC-PKAKYV 265

  Fly   272 LKCDDDTFVNIPNLLNFLLGGTIPLYNDTLDYHDRSTYLVTAPQTRLKASSDVLYGHQFCNVVPV 336
            ||.|||.|:|:|.||..:                          :.|||:. .:||.:..|..|:
  Fly   266 LKTDDDMFINVPKLLTLI--------------------------STLKANR-TIYGRRAENWKPI 303

  Fly   337 SEVSSKWYMPSYMYKPESYPKYLSGAGYLMSIDVVQRLFEASLNTTLVYLEDVYITGLCAQKAKI 401
            ....||:::.:..|...::|.:.:|..||::.|:|..|:..||||..:.||||:.||:.|:...|
  Fly   304 RNRWSKYHISNAQYGKPTFPYFTTGPAYLLTGDIVHALYVQSLNTAFLKLEDVFTTGIVAESLNI 368

  Fly   402 NRHHHPLFSFAHSK-QMCAFKGTITQHQLKDDSMVSAWNYVSNYSIKC 448
            .|.:....:...:| :.|..:..||.|.::::...:.||.:.:.:|||
  Fly   369 RRVNVREMANTRTKFETCHIRDKITIHMVRNNEQFTLWNMLLDDTIKC 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GalT1	NP_788328.1	Galactosyl_T	204..407	CDD:304462	63/202 (31%)
CG8673	NP_609182.1	Galactosyl_T	186..374	CDD:304462	71/259 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464999
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	143	1.000	Inparanoid score	I4358
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4848
orthoMCL	1	0.900	-	-		OOG6_100261
Panther	1	1.100	-	-	P	PTHR11214
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
	9	8.800