DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GalT1 and brn

DIOPT Version :9

Sequence 1:	NP_788328.1	Gene:	GalT1 / 36279	FlyBaseID:	FBgn0053145	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_476901.1	Gene:	brn / 31358	FlyBaseID:	FBgn0000221	Length:	325	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	105/432 - (24%)
Similarity:	168/432 - (38%)	Gaps:	140/432 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 KAKLRKRQLRNRMPLPRMLRRLGCYTLSAFLI--CGLLLVYLPLVYLDVH------------KRS 96
            ::|.||..||..:.||.:|           |:  || ||.:|..:..:.|            ..|
  Fly     2 QSKHRKLLLRCLLVLPLIL-----------LVDYCG-LLTHLHELNFERHFHYPLNDDTGSGSAS 54

  Fly    97 AGL--------PDWTSETSRSIADYLDIGLSSGVIVPKDFCRNKTFLVIAVCTGVDNFIQRHTIR 153
            :||        |.:|:|                  ||.|   ....|.:.:.:.|.|..:|..||
  Fly    55 SGLDKFAYLRVPSFTAE------------------VPVD---QPARLTMLIKSAVGNSRRREAIR 98

  Fly   154 ETWGNTTEFNYPAFGKLHGHLKGHYLPPLPDRLKMYGDYLSGEGQSLTASVRIVFIVGRQKDEAM 218
            .|||.                                     ||:.....:|.||::|..:|..
  Fly    99 RTWGY-------------------------------------EGRFSDVHLRRVFLLGTAEDSE- 125

  Fly   219 LGNETLNRIHIESEKYNDIIQENFVDSYNNLTLKSVMALKHISRSCFNTAVYFLKCDDDTFVNIP 283
                  ..:..||.::.||:|..|.|:|.|.|||:::.::..|.. ||.:.::|..|||.:|:..
  Fly   126 ------KDVAWESREHGDILQAEFTDAYFNNTLKTMLGMRWASDQ-FNRSEFYLFVDDDYYVSAK 183

  Fly   284 NLLNFLLGGTIPLYNDTLDYHDRSTYLVTAPQTRLKASSDVLY-GHQFCNVVPVSEVSSKWYMPS 347
            |:|.||..|                        |.....::|: ||.| ...|:....||||:..
  Fly   184 NVLKFLGRG------------------------RQSHQPELLFAGHVF-QTSPLRHKFSKWYVSL 223

  Fly   348 YMYKPESYPKYLSGAGYLMSIDVVQRLFEASLNTTLVYLEDVYITGLCAQKAKINRHHHPLFSFA 412
            ..|..:.:|.|::...:::|...:::|:.||::..|...:|||: |:.|.||.|:..|...|.|.
  Fly   224 EEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLPLFRFDDVYL-GIVALKAGISLQHCDDFRFH 287

  Fly   413 HSKQMCAFKG------TITQHQLKD-DSMVSAWNYV--SNYS 445
            ..    |:||      .|..|:..| :.|...||..  :||:
  Fly   288 RP----AYKGPDSYSSVIASHEFGDPEEMTRVWNECRSANYA 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GalT1	NP_788328.1	Galactosyl_T	204..407	CDD:304462	57/203 (28%)
brn	NP_476901.1	Galactosyl_T	92..282	CDD:250845	65/260 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45465009
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I2616
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24800
orthoMCL	1	0.900	-	-		OOG6_100261
Panther	1	1.100	-	-	P	PTHR11214
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
	9	8.800