DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GalT1 and B3gnt8

DIOPT Version :9

Sequence 1:	NP_788328.1	Gene:	GalT1 / 36279	FlyBaseID:	FBgn0053145	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001100962.1	Gene:	B3gnt8 / 308440	RGDID:	1305374	Length:	389	Species:	Rattus norvegicus

Alignment Length:	447	Identity:	99/447 - (22%)
Similarity:	168/447 - (37%)	Gaps:	127/447 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SKAKLRKRQLRNRMPLP-----------RMLRRLG-CYTLSAFLICGLLLVYLPLVYLDVHKRSA 97
            |::.|:|.:.|..:|.|           .:..||| ...||:             .|.:..:|..
  Rat    27 SESWLKKAEPRGALPSPTPPSAEPTLPTNLSARLGQTGPLSS-------------AYWNQQQRQL 78

  Fly    98 G-LPD-----WTSETSRSIADYL------------------DIGLSSGVIVPKDFCRNK--TFLV 136
            | ||.     |.|..:..|.|::                  .:.|.:|...|...|.:|  .:|:
  Rat    79 GVLPSSDCQTWGSVAASEILDFILYPQDLRRFLLSAACRSFPLWLPAGEGSPVASCSDKDVPYLL 143

  Fly   137 IAVCTGVDNFIQRHTIRETWGNTTEFNYPAFGKLHGHLKGHYLPPLPDRLKMYGDYLSGEGQSLT 201
            :||.:...:|..|..:|||||                                         |..
  Rat   144 LAVKSEPGHFAARQAVRETWG-----------------------------------------SPV 167

  Fly   202 ASVRIVFIVGRQKDEAMLGNETLNRIHIESEKYNDIIQENFVDSYNNLTLKSVMALKHISRSCFN 266
            |..|::|::|  ....|.|.:..:.:..||.:|.|::..:|:|...|.|||.::.|..:|..|..
  Rat   168 AGTRLLFLLG--SPLGMGGPDLTSLVTWESRRYGDLLLWDFLDVPYNRTLKDLLLLTWLSHHCPK 230

  Fly   267 TAVYFLKCDDDTFVNIPNLLNFLLGGTIPLYNDTLDYHDRSTYLVTAPQTRLKASSDVLY-GHQF 330
            .: :.|:..|:.||:||.||.                     :|...|.|..::    || |..|
  Rat   231 VS-FVLQVQDNAFVHIPALLE---------------------HLQALPPTWARS----LYLGEVF 269

  Fly   331 CNVVPVSEVSSKWYMPSYMYKPESYPKYLSGAGYLMSIDVVQRLFEASLNTTLVYLEDVYITGLC 395
            ....|:.:....:|:|...::.: ||.|.||.||::|..:...|.:|:........:||| ||.|
  Rat   270 TQAKPLRKPGGPFYVPKTFFEGD-YPAYASGGGYVISGRLAPWLLQAAARVAPFPFDDVY-TGFC 332

  Fly   396 AQKAKINRHHHPLFSFA----HSKQMCAFKGTITQHQLKDDSMVSAWNYVSNYSIKC 448
            .:...:....||.|..|    .::..||.:|.:..|.:.....:..|.::....::|
  Rat   333 FRALGLAPRAHPGFLTAWPAERTRDPCAVRGLLLVHPVSPQDTIWLWRHLWVPELRC 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GalT1	NP_788328.1	Galactosyl_T	204..407	CDD:304462	52/203 (26%)
B3gnt8	NP_001100962.1	Galactosyl_T	154..341	CDD:419759	60/257 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D174158at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820