DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GalT1 and B3gnt8

DIOPT Version :9

Sequence 1:	NP_788328.1	Gene:	GalT1 / 36279	FlyBaseID:	FBgn0053145	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001031817.1	Gene:	B3gnt8 / 232984	MGIID:	2385269	Length:	389	Species:	Mus musculus

Alignment Length:	447	Identity:	100/447 - (22%)
Similarity:	169/447 - (37%)	Gaps:	127/447 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SKAKLRKRQLRNRMPLP-----------RMLRRLG-CYTLSAFLICGLLLVYLPLVYLDVHKRSA 97
            |::.|:|.:.|..:|.|           .:..||| ...||:             .|.:..:|..
Mouse    27 SESWLKKAEPRGALPSPTPPNAEPTLPTNLSARLGQTGPLSS-------------AYWNQQQRQL 78

  Fly    98 G-LPD-----WTSETSRSIADYL------------------DIGLSSGVIVPKDFCRNK--TFLV 136
            | ||.     |.:..:..|.|::                  .:.|.:|...|...|.:|  .:|:
Mouse    79 GVLPSTDCQTWGTVAASEILDFILYPQELRRFLLSAACRSFPLWLPAGEGSPVASCSDKDVPYLL 143

  Fly   137 IAVCTGVDNFIQRHTIRETWGNTTEFNYPAFGKLHGHLKGHYLPPLPDRLKMYGDYLSGEGQSLT 201
            :||.:...:|..|..:|||||                                         |..
Mouse   144 LAVKSEPGHFAARQAVRETWG-----------------------------------------SPV 167

  Fly   202 ASVRIVFIVGRQKDEAMLGNETLNRIHIESEKYNDIIQENFVDSYNNLTLKSVMALKHISRSCFN 266
            |..|::|::|  ....|.|.:..:.:..||.:|.|::..:|:|...|.|||.::.|..:|..|.:
Mouse   168 AGTRLLFLLG--SPLGMGGPDLRSLVTWESRRYGDLLLWDFLDVPYNRTLKDLLLLTWLSHHCPD 230

  Fly   267 TAVYFLKCDDDTFVNIPNLLNFLLGGTIPLYNDTLDYHDRSTYLVTAPQTRLKASSDVLY-GHQF 330
            .. :.|:..||.||:||.||.                     :|.|.|.|..::    || |..|
Mouse   231 VN-FVLQVQDDAFVHIPALLE---------------------HLQTLPPTWARS----LYLGEIF 269

  Fly   331 CNVVPVSEVSSKWYMPSYMYKPESYPKYLSGAGYLMSIDVVQRLFEASLNTTLVYLEDVYITGLC 395
            ....|:.:....:|:|...::.: ||.|.||.||::|..:...|.:|:........:||| ||.|
Mouse   270 TQAKPLRKPGGPFYVPKTFFEGD-YPAYASGGGYVISGRLAPWLLQAAARVAPFPFDDVY-TGFC 332

  Fly   396 AQKAKINRHHHPLFSFA----HSKQMCAFKGTITQHQLKDDSMVSAWNYVSNYSIKC 448
            .:...:....||.|..|    .::..||.:|.:..|.:.....:..|.::....::|
Mouse   333 FRALGLAPRAHPGFLTAWPAERTRDPCAVRGLLLVHPVSPQDTIWLWRHLWVPELQC 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GalT1	NP_788328.1	Galactosyl_T	204..407	CDD:304462	54/203 (27%)
B3gnt8	NP_001031817.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..57		3/20 (15%)
B3gnt8	NP_001031817.1	Galactosyl_T	154..341	CDD:389837	62/257 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D174158at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820