DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GalT1 and B3GNT3

DIOPT Version :9

Sequence 1:	NP_788328.1	Gene:	GalT1 / 36279	FlyBaseID:	FBgn0053145	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_055071.2	Gene:	B3GNT3 / 10331	HGNCID:	13528	Length:	372	Species:	Homo sapiens

Alignment Length:	442	Identity:	97/442 - (21%)
Similarity:	167/442 - (37%)	Gaps:	123/442 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 RQLRNRMPLPRMLRRLGCYTLSAFLICGLLLVYLPLVYLDVHKRSAGLPD---WTSETSR----- 108
            :.||:|.|...::..:|.:||..|    .|||..|.  ..|.::...:|:   |.:..:|
Human     2 KYLRHRRPNATLILAIGAFTLLLF----SLLVSPPT--CKVQEQPPAIPEALAWPTPPTRPAPAP 60

  Fly   109 -----SIADYLDIGLSSGVI-----------------VPKDFCRNKTFLVIAVCTGVDNFIQRHT 151
                 |:..:.|.......:                 ||...|....||::.:.:...|:::|..
Human    61 CHANTSMVTHPDFATQPQHVQNFLLYRHCRHFPLLQDVPPSKCAQPVFLLLVIKSSPSNYVRREL 125

  Fly   152 IRETWGNTTEFNYPAFGKLHGHLKGHYLPPLPDRLKMYGDYLSGEGQSLTASVRIVFIVGRQKD- 215
            :|.|||...        |:.|                             ..:|::|:||...:
Human   126 LRRTWGRER--------KVRG-----------------------------LQLRLLFLVGTASNP 153

  Fly   216 -EAMLGNETLNRIHIESEKYNDIIQENFVDSYNNLTLKSVMALKHISRSCFNTAVYFLKCDDDTF 279
             ||...|..|   .:|::.:.||:|.:|.||:.|||||.|:.|:.....|.| |.:.|..|||.|
Human   154 HEARKVNRLL---ELEAQTHGDILQWDFHDSFFNLTLKQVLFLQWQETRCAN-ASFVLNGDDDVF 214

  Fly   280 VNIPNLLNFLLGGTIPLYNDTLDYHDRSTYLVTAPQTRLKASSDVLYGHQFCNVVPVSEVSSKWY 344
            .:..|::.:            |..||...:|              ..|....||.|:....||:|
Human   215 AHTDNMVFY------------LQDHDPGRHL--------------FVGQLIQNVGPIRAFWSKYY 253

  Fly   345 MPSYMYKPESYPKYLSGAGYLMSIDVVQRLFEASLNTTLVYLEDVYITGLCAQKAKINRHHHP-- 407
            :|..:.:.|.||.|..|.|:|:|......|..|:....:..::||:: |:|.:...:....|.
Human   254 VPEVVTQNERYPPYCGGGGFLLSRFTAAALRRAAHVLDIFPIDDVFL-GMCLELEGLKPASHSGI 317

  Fly   408 -----------LFSFAHSKQMCAFKGTITQHQLKDDSMVSAWNYVSNYSIKC 448
                       |.||    ..|.::..:..|:.....|:..|:.::..::.|
Human   318 RTSGVRAPSQRLSSF----DPCFYRDLLLVHRFLPYEMLLMWDALNQPNLTC 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GalT1	NP_788328.1	Galactosyl_T	204..407	CDD:304462	57/204 (28%)
B3GNT3	NP_055071.2	Galactosyl_T	122..311	CDD:389837	64/256 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820