DRSC/TRiP Functional Genomics Resources

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Protein Alignment ADD1 and DNMT3L

DIOPT Version :9

Sequence 1:NP_725094.1 Gene:ADD1 / 36278 FlyBaseID:FBgn0026573 Length:1199 Species:Drosophila melanogaster
Sequence 2:NP_037501.2 Gene:DNMT3L / 29947 HGNCID:2980 Length:387 Species:Homo sapiens


Alignment Length:162 Identity:40/162 - (24%)
Similarity:58/162 - (35%) Gaps:32/162 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 ATPSPSPLAK--LDADFTSSKFEMHPSLSDEERRFYLKMYPNVDLV------NQRKVH--CTVC- 69
            |.|:..|.|:  :|.....|. |:..|:|....|         ||:      |||.:.  |..| 
Human     3 AIPALDPEAEPSMDVILVGSS-ELSSSVSPGTGR---------DLIAYEVKANQRNIEDICICCG 57

  Fly    70 KLHLGTAPAAESNIKMHPILRVTHCVKCHDFYNSGEFSKGEDGSELYCRWCGQGGEVYCCST--C 132
            .|.:.|         .||:.....|..|.|.:....|...:||.:.||..|..|..:..|..  |
Human    58 SLQVHT---------QHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDC 113

  Fly   133 PYVFCKSCIVKNLSKGVIVDIEQNENWNCFSC 164
            ...:|..|:...:..|....:....||.|:.|
Human   114 TRCYCFECVDSLVGPGTSGKVHAMSNWVCYLC 145

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ADD1NP_725094.1 ADDz_ATRX 62..164 CDD:277252 25/106 (24%)
DNMT3LNP_037501.2 PHD_SF 47..169 CDD:304600 26/108 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
10.960

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