Protein Alignment Zip48C and Slc39a8

DIOPT Version :10

• Sequence 1: NP_610712.1
• Gene: Zip48C / 36273
• FlyBaseID: FBgn0033665
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_080504.3
• Gene: Slc39a8 / 67547
• MGIID: 1914797
• Length: 462
• Species: Mus musculus
• Alignment Length: 375
• Identity: 80/375 - (21%)
• Similarity: 142/375 - (37%)
• Gaps: 94/375 - (25%)

  Fly     4 GYG--PVT----QALLGTLLTWGLTAAGAALVIFVRGNQRRSLDAALGFAAGVMIAASFWSLLKP 62
            |||  .||    .:|||.:||          .:..:....:.|...:|.|.|.:.:.:.:.|:..
Mouse   130 GYGFLSVTIINLASLLGLILT----------PLIKKSYFPKILTYFVGLAIGTLFSNAIFQLIPE 184

  Fly    63 AIEMAESSHLYGVYAFLPVAGGFLLGSIFVYGCDKLMSYLGLNSTNMMIQMTQSKAKADIAIED- 126
            |            :.|.|....::..::.|:|...::.::. .:..|:::............:|
Mouse   185 A------------FGFNPKIDNYVEKAVAVFGGFYMLFFVE-RTLKMLLKTYGQNDHTHFRNDDF 236

  Fly   127 -SKRNGVAPDRLASKSLDSFS----------------DCLSVQHSGESRRRKKGASINEMEQCTY 174
             ||.....|..|...:::..:                |.:||....:.:        .|...||.
Mouse   237 GSKEKTHQPKTLPLPAVNGVTCYANPAVTEPNGHIHFDTVSVVSLQDGK--------TEPSSCTC 293

  Fly   175 TTPEEQQRAEDALSQWKRIMLLVVAITVHNIPEGLAVGVSFGAIGSTNSSTFESARNLAIGIGI- 238
            .  :..:.:|.....|    ::.:...:||..:|||:|.         |.|....:.|:..|.|
Mouse   294 L--KGPKLSEIGTIAW----MITLCDALHNFIDGLAIGA---------SCTLSLLQGLSTSIAIL 343

  Fly   239 -QNFPEGLAVSLPLHAAGFSVKRALWYGQLSG---MVEPIFGVLGAVAVTFA-NLILPYALSFAA 298
             :.||..|...:.|..||.|.::||.:..||.   .|...||:|  |...|| |:|  :||  |.
Mouse   344 CEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL--VGNNFAPNII--FAL--AG 402

  Fly   299 GAMIYIVSDDILPEAH------ASGNGTIATW------GTVSGFLIMMCL 336
            |..:||...|:.||.:      .:|..|..|:      |.::||..::.:
Mouse   403 GMFLYISLADMFPEMNDMLREKVTGRQTDFTFFMIQNAGMLTGFTAILLI 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zip48C	NP_610712.1	ZupT	23..339	CDD:440197	70/350 (20%)
Slc39a8	NP_080504.3	Zip	126..453	CDD:396884	80/375 (21%)
		XEXPHE-motif. /evidence=ECO:0000250|UniProtKB:Q9C0K1	345..350		2/4 (50%)