Protein Alignment Zip48C and SLC39A8

DIOPT Version :9

• Sequence 1: NP_610712.1
• Gene: Zip48C / 36273
• FlyBaseID: FBgn0033665
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: XP_024309952.1
• Gene: SLC39A8 / 64116
• HGNCID: 20862
• Length: 475
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 88/344 - (25%)
• Similarity: 131/344 - (38%)
• Gaps: 66/344 - (19%)

  Fly     4 GYG--PVT----QALLGTLLTWGLTAAGAALVIFVRGNQRRSLDAALGFAAGVMIAASFWSLLKP 62
            |||  .||    .:|||.:||          .:..:....:.|...:|.|.|.:.:.:.:.|:..
Human   130 GYGFLSVTIINLASLLGLILT----------PLIKKSYFPKILTFFVGLAIGTLFSNAIFQLIPE 184

  Fly    63 AIEMAESSHLYGVYAFLPVAGGFLLGSIFVYGCDKLMSYLGLN------STNMMIQMTQSKAKAD 121
            |.........| |...:.|.|||.|...|......|:...|.|      :.|...|....:.||.
Human   185 AFGFDPKVDSY-VEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFGNDNFGPQEKTHQPKAL 248

  Fly   122 IAIEDSKRNGV---APDRLASKSLDSFSDCLSVQHSGESRRRKKGASINEMEQCTYTTPEEQQRA 183
            .||     |||   |...:...:.....|.:||....:.::        |...||..  :..:.:
Human   249 PAI-----NGVTCYANPAVTEANGHIHFDNVSVVSLQDGKK--------EPSSCTCL--KGPKLS 298

  Fly   184 EDALSQWKRIMLLVVAITVHNIPEGLAVGVSFGAIGSTNSSTFESARNLAIGIGI--QNFPEGLA 246
            |.....|    ::.:...:||..:|||:|.         |.|....:.|:..|.|  :.||..|.
Human   299 EIGTIAW----MITLCDALHNFIDGLAIGA---------SCTLSLLQGLSTSIAILCEEFPHELG 350

  Fly   247 VSLPLHAAGFSVKRALWYGQLSG---MVEPIFGVLGAVAVTFA-NLILPYALSFAAGAMIYIVSD 307
            ..:.|..||.|.::||.:..||.   .|...||:|  |...|| |:|  :||  |.|..:||...
Human   351 DFVILLNAGMSTRQALLFNFLSACSCYVGLAFGIL--VGNNFAPNII--FAL--AGGMFLYISLA 409

  Fly   308 DILPEAHASGNGTIATWGT 326
            |:.||.:......|..|.|
Human   410 DMFPEMNDMLREKIIKWAT 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zip48C	NP_610712.1	ZupT	23..340	CDD:223505	78/319 (24%)
SLC39A8	XP_024309952.1	Zip	126..422	CDD:308248	85/336 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810