Protein Alignment Zip48C and SLC39A10

DIOPT Version :10

• Sequence 1: NP_610712.1
• Gene: Zip48C / 36273
• FlyBaseID: FBgn0033665
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: XP_005246746.3
• Gene: SLC39A10 / 57181
• HGNCID: 20861
• Length: 952
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 81/371 - (21%)
• Similarity: 129/371 - (34%)
• Gaps: 104/371 - (28%)

  Fly    20 GLTAAGAALVIFV--------------RGNQ--------------RRSLDAALGFAAGVMIAASF 56
            ||.|.|...::|:              ||.|              |:..|..|.....     |.
Human   619 GLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEESTIGRKLSDHKLNNTPD-----SD 678

  Fly    57 WSLLKPAIEMAESSHLYGVYAFLPVAGGFLLGSIFVYGCDKLMSYLGLNSTNM--MIQMTQSKAK 119
            |..|||                       |.|:     .|.::|...||.|.:  :....:|..|
Human   679 WLQLKP-----------------------LAGT-----DDSVVSEDRLNETELTDLEGQQESPPK 715

  Fly   120 ADIAIEDSKRNGVAPDRLASKSLDSFSD----CLSVQHSGESRR--RKKGASINEMEQCTYTTP- 177
            ..:.||:.|    ..|...|..|.:..:    ..:..|.||::.  ||.....:.........|
Human   716 NYLCIEEEK----IIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPC 776

  Fly   178 ---EEQQRAEDALSQWKRIMLLVVAITVHNIPEGLAVGVSF--GAIGSTNSSTFESARNLAIGIG 237
               .:.:....|...|    ::::...:||..:|||:|.:|  |..|..::|         |.:.
Human   777 HSGSDLKETGIANIAW----MVIMGDGIHNFSDGLAIGAAFSAGLTGGISTS---------IAVF 828

  Fly   238 IQNFPEGLAVSLPLHAAGFSVKRALWYGQLSGMVEPIFGVLGAVAVTFANLILPYALSFAAGAMI 302
            ....|..|.....|..||.:||:|:.|..||.|:..|..::|.....:||.|..:..:..||..:
Human   829 CHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFL 893

  Fly   303 YIVSDDILPE-AHASGNG-----------TIATWGTVSGFLIMMCL 336
            |:...|:||| .|..|:.           .:...|.:.||.||:.:
Human   894 YVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVI 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zip48C	NP_610712.1	ZupT	23..339	CDD:440197	79/368 (21%)
SLC39A10	XP_005246746.3	Zip	525..940	CDD:396884	81/371 (22%)