DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zip48C and Slc39a11

DIOPT Version :9

Sequence 1:	NP_610712.1	Gene:	Zip48C / 36273	FlyBaseID:	FBgn0033665	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_006247726.1	Gene:	Slc39a11 / 287796	RGDID:	1311981	Length:	374	Species:	Rattus norvegicus

Alignment Length:	350	Identity:	188/350 - (53%)
Similarity:	235/350 - (67%)	Gaps:	19/350 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIPGYGPVTQALLGTLLTWGLTAAGAALVIFVRGNQRRSLDAALGFAAGVMIAASFWSLLKPAIE 65
            |:.||..|:||||||..||.:||||||||......|||.||.:||||||||:|||:||||.||:|
  Rat    33 MLQGYSSVSQALLGTFFTWAMTAAGAALVFIFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVE 97

  Fly    66 MAESSHLYGVYAFLPVAGGFLLGSIFVYGCDKLMSYLG----------LNSTNMMIQMTQSKAKA 120
            ||.||..:|.:||.|||.||.||:.|||..|.||.:||          ||....:::.:..|..|
  Rat    98 MATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMPHLGAGEDPQTALALNLDPALVKKSDLKDPA 162

  Fly   121 DIAIEDSKRNGVAPDRLASKSLDSFSDCLSVQHSGESRRRKKGASINEMEQCTYTTPEEQQRAED 185
            .:         :.|:|..|..:.|.......:.:||..:|||.|:.:..|....:.|......:.
  Rat   163 SL---------LFPERELSIRIGSTVLLSDKRENGEVYQRKKLAATDFPEGAAPSGPVHGNSGQP 218

  Fly   186 ALSQWKRIMLLVVAITVHNIPEGLAVGVSFGAIGSTNSSTFESARNLAIGIGIQNFPEGLAVSLP 250
            .:|.|:||.||::|||:|||||||||||.|||:..|.|:||||||||||||||||||||||||||
  Rat   219 GVSSWRRIALLILAITIHNIPEGLAVGVGFGAVEKTASATFESARNLAIGIGIQNFPEGLAVSLP 283

  Fly   251 LHAAGFSVKRALWYGQLSGMVEPIFGVLGAVAVTFANLILPYALSFAAGAMIYIVSDDILPEAHA 315
            |..||||..:|.|||||||||||:.||.||.||..|..:|||||:||||||:|:|.|||:|||..
  Rat   284 LRGAGFSTWKAFWYGQLSGMVEPLAGVFGAFAVVLAEPVLPYALAFAAGAMVYVVMDDIIPEAQI 348

  Fly   316 SGNGTIATWGTVSGFLIMMCLEVAL 340
            ||||.:|:|.::.||::||.|:|.|
  Rat   349 SGNGKLASWASILGFVVMMSLDVGL 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zip48C	NP_610712.1	ZupT	23..340	CDD:223505	174/326 (53%)
Slc39a11	XP_006247726.1	ZupT	38..374	CDD:223505	184/344 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349541
Domainoid	1	1.000	319	1.000	Domainoid score	I1211
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12331
Inparanoid	1	1.050	349	1.000	Inparanoid score	I2220
OMA	1	1.010	-	-		QHG55224
OrthoDB	1	1.010	-	-		D398036at33208
OrthoFinder	1	1.000	-	-		FOG0001712
OrthoInspector	1	1.000	-	-		oto96507
orthoMCL	1	0.900	-	-		OOG6_100747
Panther	1	1.100	-	-	LDO	PTHR11040
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3669
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810